Search Results - "Ranallo, Ryan T."

Virulence, Inflammatory Potential, and Adaptive Immunity Induced by Shigella flexneri msbB Mutants by Ranallo, Ryan T, Kaminski, Robert W, George, Tonia, Kordis, Alexis A, Chen, Qing, Szabo, Kathleen, Venkatesan, Malabi M

“…The ability of genetically detoxified lipopolysaccharide (LPS) to stimulate adaptive immune responses is an ongoing area of investigation with significant…”
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The State of Microbiome Science at the Intersection of Infectious Diseases and Antimicrobial Resistance by Ranallo, Ryan T, McDonald, L Clifford, Halpin, Alison Laufer, Hiltke, Thomas, Young, Vincent B

“…Abstract Along with the rise in modern chronic diseases, ranging from diabetes to asthma, there are challenges posed by increasing antibiotic resistance, which…”
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Vaccines for Healthcare-associated Infections: Promise and Challenge by Knisely, Jane M., Liu, Baoying, Ranallo, Ryan T., Zou, Lanling

“…As antibiotic resistance increases and the rate of antibiotic development slows, it is becoming more urgent to develop novel approaches to prevent and mitigate…”
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Construction and Characterization of Bivalent Shigella flexneri 2a Vaccine Strains SC608(pCFAI) and SC608(pCFAI/LTB) That Express Antigens from Enterotoxigenic Escherichia coli by RANALLO, Ryan T, PIYUMI FONSEKA, C, CASSELS, Fred, SRINIVASAN, Jay, VENKATESAN, Malabi M

“…Classifications Services IAI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Further characterization of Shigella sonnei live vaccine candidates WRSs2 and WRSs3-plasmid composition, invasion assays and Sereny reactions by Bedford, Lisa, Fonseka, Suramya, Boren, Tara, Ranallo, Ryan T., Suvarnapunya, Akamol E., Lee, James E., Barnoy, Shoshana, Venkatesan, Malabi M.

“…Shigella sonnei live vaccine candidates WRSs2 and WRSs3 are principally attenuated by the loss of the virG(icsA) gene that prevents bacterial spread. In…”
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The ATP-dependent Chromatin Remodeling Enzyme Fun30 Represses Transcription by Sliding Promoter-proximal Nucleosomes by Byeon, Boseon, Wang, Wei, Barski, Artem, Ranallo, Ryan T., Bao, Kan, Schones, Dustin E., Zhao, Keji, Wu, Carl, Wu, Wei-Hua

“…The evolutionarily conserved ATP-dependent chromatin remodeling enzyme Fun30 has recently been shown to play important roles in heterochromatin silencing and…”
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Safety and immunogenicity of an intranasal Shigella flexneri 2a Invaplex 50 vaccine by Riddle, Mark S, Kaminski, Robert W, Williams, Carlos, Porter, Chad, Baqar, Shahida, Kordis, Alexis, Gilliland, Theron, Lapa, Joyce, Coughlin, Melissa, Soltis, Chris, Jones, Erica, Saunders, Jackie, Keiser, Paul B, Ranallo, Ryan T, Gormley, Robert, Nelson, Michael, Turbyfill, K. Ross, Tribble, David, Oaks, Edwin V

“…Highlights ► Intranasal immunization stimulates intestinal IgA in humans. ► Intranasal immunization with Shigella Invaplex subunit vaccine is safe and…”
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Live-attenuated Shigella vaccines by Venkatesan, Malabi M, Ranallo, Ryan T

“…Several live-attenuated Shigella vaccines, with well-defined mutations in specific genes, have shown great promise in eliciting significant immune responses…”
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Two live attenuated Shigella flexneri 2a strains WRSf2G12 and WRSf2G15: A new combination of gene deletions for 2nd generation live attenuated vaccine candidates by Ranallo, Ryan T, Fonseka, Suramya, Boren, Tara L, Bedford, Lisa A, Kaminski, Robert W, Thakkar, Sejal, Venkatesan, Malabi M

“…Highlights ► New, second-generation live attenuated Shigella flexneri 2a vaccine candidates. ► WRSf2G12 and WRSf2G15 are as invasive as parental strain 2457T…”
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Development of an Aotus nancymaae model for Shigella Vaccine immunogenicity and efficacy studies by Gregory, Michael, Kaminski, Robert W, Lugo-Roman, Luis A, Galvez Carrillo, Hugo, Tilley, Drake Hamilton, Baldeviano, Christian, Simons, Mark P, Reynolds, Nathanael D, Ranallo, Ryan T, Suvarnapunya, Akamol E, Venkatesan, Malabi M, Oaks, Edwin V

“…Several animal models exist to evaluate the immunogenicity and protective efficacy of candidate Shigella vaccines. The two most widely used nonprimate models…”
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Immunogenicity and characterization of WRSF2G11: A second generation live attenuated Shigella flexneri 2a vaccine strain by Ranallo, Ryan T, Thakkar, Sejal, Chen, Qing, Venkatesan, Malabi M

“…Abstract Recent clinical trials involving live attenuated Shigella vaccine strains SC602 and WRSS1 have revealed that deletion of the virG ( icsA ) gene…”
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Self-adjuvanting bacterial vectors expressing pre-erythrocytic antigens induce sterile protection against malaria by Bergmann-Leitner, Elke S, Hosie, Heather, Trichilo, Jessica, Deriso, Elizabeth, Ranallo, Ryan T, Alefantis, Timothy, Savranskaya, Tatyana, Grewal, Paul, Ockenhouse, Christian F, Venkatesan, Malabi M, Delvecchio, Vito G, Angov, Evelina

“…Genetically inactivated, Gram-negative bacteria that express malaria vaccine candidates represent a promising novel self-adjuvanting vaccine approach. Antigens…”
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Osmoregulated periplasmic glucans synthesis gene family of Shigella flexneri by Liu, Liu, Dharne, Mahesh, Kannan, Porteen, Smith, Allen, Meng, Jianghong, Fan, Mingtao, Boren, Tara L, Ranallo, Ryan T, Bhagwat, Arvind A

“…Osmoregulated periplasmic glucans (OPGs) of food- and water-borne enteropathogen Shigella flexneri were characterized. OPGs were composed of 100% glucose with…”
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Developing live Shigella vaccines using λ Red recombineering by Ranallo, Ryan T., Barnoy, Shoshana, Thakkar, Sejal, Urick, Tonia, Venkatesan, Malabi M.

“…Abstract Live attenuated Shigella vaccines have shown promise in inducing protective immune responses in human clinical trials and as carriers of heterologous…”
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Safety and Colonization of Two Novel virG(icsA)-based Live Shigella sonnei Vaccine Strains in Rhesus Macaques (Macaca mulatta) by Collins, Todd A, Barnoy, Shoshana, Baqar, Shahida, Ranallo, Ryan T, Nemelka, Kevin W, Venkatesan, Malabi M

“…Shigella are gram-negative bacterium that cause bacillary dysentery (shigellosis). Symptoms include diarrhea and discharge of bloody mucoid stools, accompanied…”
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TFIIA Interacts with TFIID via Association with TATA-Binding Protein and TAF40 by Kraemer, Susan M., Ranallo, Ryan T., Ogg, Ryan C., Stargell, Laurie A.

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Reevaluation of Transcriptional Regulation by TATA-Binding Protein Oligomerization:  Predominance of Monomers by Campbell, Kathleen M, Ranallo, Ryan T, Stargell, Laurie A, Lumb, Kevin J

“…The TATA-binding protein (TBP) plays an important role in transcriptional initiation by all three nuclear RNA polymerases. TBP contains a conserved C-terminal…”
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Taking Microbiome Science to the Next Level: Recommendations to Advance the Emerging Field of Microbiome-Based Therapeutics and Diagnostics by Britton, Robert A., Verdu, Elena F., Di Rienzi, Sara C., Reyes Muñoz, Alejandro, Tarr, Phillip I., Preidis, Geoffrey A., Tomeo, Nicholas J., Ranallo, Ryan T., Pimentel, Mark, Chang, Eugene

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A TATA-Binding Protein Mutant Defective for TFIID Complex Formation In Vivo by Ranallo, Ryan T., Struhl, Kevin, Stargell, Laurie A.

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Two live attenuatedShigella flexneri2a strains WRSf2G12 and WRSf2G15: A new combination of gene deletions for 2nd generation live attenuated vaccine candidates by Ranallo, Ryan T, Fonseka, Suramya, Boren, Tara L, Bedford, Lisa A, Kaminski, Robert W, Thakkar, Sejal, Venkatesan, Malabi M

“…Highlights * New, second-generation live attenuatedShigella flexneri2a vaccine candidates. * WRSf2G12 and WRSf2G15 are as invasive as parental strain 2457T in…”
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