Search Results - "Rana, Santanu"
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Arginyltransferase knockdown attenuates cardiac hypertrophy and fibrosis through TAK1-JNK1/2 pathway
Published in Scientific reports (17-01-2020)“…Myocardial hypertrophy, an inflammatory condition of cardiac muscles is a maladaptive response of the heart to biomechanical stress, hemodynamic or…”
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Molecular and cellular pathophysiology of circulating cardiomyocyte-specific cell free DNA (cfDNA): Biomarkers of heart failure and potential therapeutic targets
Published in Genes & diseases (01-05-2023)“…Pathological cardiac damage during heart failure is associated with cell death and damage associated molecular patterns (DAMPs) release which triggers a…”
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Author Correction: Arginyltransferase knockdown attenuates cardiac hypertrophy and fibrosis through TAK1-JNK1/2 pathway
Published in Scientific reports (25-06-2020)“…An amendment to this paper has been published and can be accessed via a link at the top of the paper…”
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Synchronized Orchestration of miR-99b and let-7g Positively Regulates Rotavirus Infection by Modulating Autophagy
Published in Scientific reports (04-02-2019)“…Rotavirus (RV), the major etiological agent of viral gastroenteritis in young children, kills over 200 thousand infants each year. In spite of available…”
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Combinatorial Effects of miRNAs in HSV-2 Infection of Macrophages: An In Silico and In Vitro Integration Approach
Published in Vaccines (Basel) (01-09-2023)“…The rising issues of herpes simplex virus (HSV)-2 drug ramifications have encouraged the researchers to look for new and alternative approaches that pose…”
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Myocardin ablation in a cardiac-renal rat model
Published in Scientific reports (10-04-2019)“…Cardiorenal syndrome is defined by primary heart failure conditions influencing or leading to renal injury or dysfunction. Dilated cardiomyopathy (DCM) is a…”
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Abstract 126: Peroxisomal Proliferator Activated Receptor Alpha Overexpression in Hypertrophied Cardiomyocytes Restores Mitochondrial Integrity and Function
Published in Circulation research (21-07-2017)“…Abstract only Cardiac tissue engineering is an interdisciplinary field that engineers modulation of viable molecular milieu to restore, maintain or improve…”
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Pesticide-induced oxidative stress in laboratory and field populations of native honey bees along intensive agricultural landscapes in two Eastern Indian states
Published in Apidologie (2015)“…Pesticides have been cited as one of the major drivers of pollinator loss. However, little is known about pesticide impacts on natural populations of native…”
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Myocyte-Derived Hsp90 Modulates Collagen Upregulation via Biphasic Activation of STAT-3 in Fibroblasts during Cardiac Hypertrophy
Published in Molecular and cellular biology (01-03-2017)“…Signal transducer and activator of transcription 3 (STAT-3)-mediated signaling in relation to upregulated collagen expression in fibroblasts during cardiac…”
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Modulation of NFKB1/p50 by ROS leads to impaired ATP production during MI compared to cardiac hypertrophy
Published in Journal of cellular biochemistry (01-02-2018)“…Pathological hypertrophy and myocardial infarction (MI) are two etiologically different cardiac disorders having differential molecular mechanisms of disease…”
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Improved bioavailability of targeted Curcumin delivery efficiently regressed cardiac hypertrophy by modulating apoptotic load within cardiac microenvironment
Published in Toxicology and applied pharmacology (01-01-2016)“…Cardiomyocyte apoptosis acts as a prime modulator of cardiac hypertrophy leading to heart failure, a major cause of human mortality worldwide. Recent…”
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Cardiomyocyte-specific regression of nitrosative stress-mediated S-Nitrosylation of IKKγ alleviates pathological cardiac hypertrophy
Published in Cellular signalling (01-10-2022)“…IKKγ prototypically promotes NFκBp65 activity by regulating the assembly of the IKK holocomplex. In hypertrophied cardiomyocytes, the p65-p300 complex-induced…”
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Nanotized PPARα Overexpression Targeted to Hypertrophied Myocardium Improves Cardiac Function by Attenuating the p53-GSK3β-Mediated Mitochondrial Death Pathway
Published in Antioxidants & redox signaling (10-02-2019)“…Metabolic remodeling of cardiac muscles during pathological hypertrophy is characterized by downregulation of fatty acid oxidation (FAO) regulator, peroxisome…”
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Hsp90/Cdc37 assembly modulates TGFβ receptor-II to act as a profibrotic regulator of TGFβ signaling during cardiac hypertrophy
Published in Cellular signalling (01-12-2015)“…Cardiac hypertrophy is accompanied by excessive collagen deposition in the heart. Despite painstaking research on this fatal disease, the precise role of…”
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Field populations of native Indian honey bees from pesticide intensive agricultural landscape show signs of impaired olfaction
Published in Scientific reports (27-07-2015)“…Little information is available regarding the adverse effects of pesticides on natural honey bee populations. This study highlights the detrimental effects of…”
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A spatio-temporal cardiomyocyte targeted vector system for efficient delivery of therapeutic payloads to regress cardiac hypertrophy abating bystander effect
Published in Journal of controlled release (28-02-2015)“…Diverse array of therapeutic regimens, drugs or siRNA, are commonly used to regress cardiac hypertrophy, although, bystander effect and lower retention of…”
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Abstract 106: microRNA-33a Regulates Myocardin Expression and Attenuates Cardiac Remodeling in Renal Artery Ligation Model of Heart Failure
Published in Circulation research (21-07-2017)“…Abstract only Myocardin (MYOCD), a cardiac specific transcriptional co-activator is up-regulated in heart failure (HF). Up-regulation of MYOCD expression has…”
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607 REGRESSION OF CARDIAC HYPERTROPHY BYCARDIOMYOCYTE SPECIFIC TARGETED DRUG DELIVERY VIA NANO-VEHICLE
Published in Journal of hypertension (01-09-2012)Get full text
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