Search Results - "Rana, Brinda K."

Effects of diet composition on weight loss, metabolic factors and biomarkers in a 1-year weight loss intervention in obese women examined by baseline insulin resistance status by Rock, Cheryl L, Flatt, Shirley W, Pakiz, Bilge, Quintana, Elizabeth L, Heath, Dennis D, Rana, Brinda K, Natarajan, Loki

“…Abstract Background Obesity is a risk factor for postmenopausal breast cancer incidence and pre- and postmenopausal breast cancer mortality, which may be…”
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Sitting Interruption Modalities during Prolonged Sitting Acutely Improve Postprandial Metabolome in a Crossover Pilot Trial among Postmenopausal Women by Patterson, Jeffrey S, Rana, Brinda K, Gu, Haiwei, Sears, Dorothy D

“…Older adults sit during most hours of the day; more than 30% are considered physically inactive. The accumulation of prolonged sitting time is an…”
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Association of Sleep Quality on Memory-Related Executive Functions in Middle Age by Rana, Brinda K, Panizzon, Matthew S, Franz, Carol E, Spoon, Kelly M, Jacobson, Kristen C, Xian, Hong, Ancoli-Israel, Sonia, Lyons, Michael, Kremen, William S

“…Sleep quality affects memory and executive function in older adults, but little is known about its effects in midlife. If it affects cognition in midlife, it…”
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Effects of Diet Composition and Insulin Resistance Status on Plasma Lipid Levels in a Weight Loss Intervention in Women by Le, Tran, Flatt, Shirley W., Natarajan, Loki, Pakiz, Bilge, Quintana, Elizabeth L., Heath, Dennis D., Rana, Brinda K., Rock, Cheryl L.

“…Background Optimal macronutrient distribution of weight loss diets has not been established. The distribution of energy from carbohydrate and fat has been…”
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Metabolic Profiling of Cognitive Aging in Midlife by Huo, Zhiguang, Rana, Brinda K, Elman, Jeremy A, Dong, Ruocheng, Engelman, Corinne D, Johnson, Sterling C, Lyons, Michael J, Franz, Carol E, Kremen, William S, Zhao, Jinying

“…Alzheimer's dementia (AD) begins many years before its clinical symptoms. Metabolic dysfunction represents a core feature of AD and cognitive impairment, but…”
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Candidate SNP Associations of Optimism and Resilience in Older Adults: Exploratory Study of 935 Community-Dwelling Adults by Rana, Brinda K., Ph.D, Darst, Burcu F., B.S, Bloss, Cinnamon, Ph.D, Shih, Pei-an Betty, Ph.D, Depp, Colin, Ph.D, Nievergelt, Caroline M., Ph.D, Allison, Matthew, M.D, Parsons, J. Kellogg, M.D., M.H.S, Schork, Nicholas, Ph.D, Jeste, Dilip V., M.D

“…Objective Optimism and resilience promote health and well-being in older adults, and previous reports suggest that these traits are heritable. We examined the…”
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Pharmacogenetics of the G protein-coupled receptors by Thompson, Miles D, Cole, David E C, Capra, Valerie, Siminovitch, Katherine A, Rovati, G Enrico, Burnham, W McIntyre, Rana, Brinda K

“…Pharmacogenetics investigates the influence of genetic variants on physiological phenotypes related to drug response and disease, while pharmacogenomics takes…”
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Population-Based Sample Reveals Gene–Gender Interactions in Blood Pressure in White Americans by Rana, Brinda K, Insel, Paul A, Payne, Samuel H, Abel, Kenneth, Beutler, Ernest, Ziegler, Michael G, Schork, Nicholas J, O’Connor, Daniel T

“…The influence of genetic contributors, such as common single nucleotide polymorphisms, on blood pressure and essential hypertension may vary with the gender…”
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Meditation-induced bloodborne factors as an adjuvant treatment to COVID-19 disease by Zuniga-Hertz, Juan P., Chitteti, Ramamurthy, Dispenza, Joe, Cuomo, Raphael, Bonds, Jacqueline A., Kopp, Elena L., Simpson, Sierra, Okerblom, Jonathan, Maurya, Svetlana, Rana, Brinda K., Miyonahara, Atsushi, Niesman, Ingrid R., Maree, Jacqueline, Belza, Gianna, Hamilton, Hillari D., Stanton, Carla, Gonzalez, David J., Poirier, Michelle A., Moeller-Bertram, Tobias, Patel, Hemal H.

“…The COVID-19 pandemic has resulted in significant morbidity and mortality worldwide. Management of the pandemic has relied mainly on SARS-CoV-2 vaccines, while…”
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The IL6 Gene Promoter SNP and Plasma IL-6 in Response to Diet Intervention by Rana, Brinda, Flatt, Shirley, Health, Dennis, Pakiz, Bilge, Quintana, Elizabeth, Natarajan, Loki, Rock, Cheryl

“…We recently reported that interleukin-6 (IL-6), an inflammatory marker associated with breast pathology and the development of breast cancer, decreases with…”
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Discovery of common human genetic variants of GTP cyclohydrolase 1 (GCH1) governing nitric oxide, autonomic activity, and cardiovascular risk by Zhang, Lian, Rao, Fangwen, Zhang, Kuixing, Khandrika, Srikrishna, Das, Madhusudan, Vaingankar, Sucheta M, Bao, Xuping, Rana, Brinda K, Smith, Douglas W, Wessel, Jennifer, Salem, Rany M, Rodriguez-Flores, Juan L, Mahata, Sushil K, Schork, Nicholas J, Ziegler, Michael G, O'Connor, Daniel T

“…GTP cyclohydrolase 1 (GCH1) is rate limiting in the provision of the cofactor tetrahydrobiopterin for biosynthesis of catecholamines and NO. We asked whether…”
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Polymorphisms and Haplotypes of the Regulator of G Protein Signaling-2 Gene in Normotensives and Hypertensives by Riddle, Evan L, Rana, Brinda K, Murthy, Kenton K, Rao, Fangwen, Eskin, Eleazar, O’Connor, Daniel T, Insel, Paul A

“…Regulator of G protein signaling (RGS) proteins stimulate the GTPase activity of Gα subunits of heterotrimeric G proteins, thereby negatively regulating G…”
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Evaluation of OPRM1 variants in heroin dependence by family-based association testing and meta-analysis by Glatt, Stephen J, Bousman, Chad, Wang, Richard S, Murthy, Kenton K, Rana, Brinda K, Lasky-Su, Jessica A, Zhu, Shao C, Zhang, Ruimin, Li, Jianhua, Zhang, Bo, Li, Jixiang, Lyons, Michael J, Faraone, Stephen V, Tsuang, Ming T

“…Abstract OPRM1 , which codes for the μ-opioid receptor, is the most frequently studied candidate gene for opioid dependence. Despite numerous allelic…”
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Common Functional Genetic Variants in Catecholamine Storage Vesicle Protein Promoter Motifs Interact to Trigger Systemic Hypertension by Zhang, Kuixing, MD, PhD, Rao, Fangwen, MD, Wang, Lei, PhD, Rana, Brinda K., PhD, Ghosh, Sajalendu, PhD, Mahata, Manjula, PhD, Salem, Rany M., PhD, Rodriguez-Flores, Juan L., PhD, Fung, Maple M., MD, Waalen, Jill, MD, MPH, Tayo, Bamidele, PhD, Taupenot, Laurent, PhD, Mahata, Sushil K., PhD, O'Connor, Daniel T., MD

“…Objectives The purpose of this study is to understand whether naturally occurring genetic variation in the promoter of chromogranin B (CHGB), a major…”
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High Polymorphism at the Human Melanocortin 1 Receptor Locus by Rana, Brinda K, Hewett-Emmett, David, Jin, Li, Chang, Benny H.-J, Sambuughin, Naymkhishing, Lin, Marie, Watkins, Scott, Bamshad, Michael, Jorde, Lynn B, Ramsay, Michele, Jenkins, Trefor, Li, Wen-Hsiung

“…Variation in human skin/hair pigmentation is due to varied amounts of eumelanin (brown/black melanins) and phaeomelanin (red/yellow melanins) produced by the…”
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Angiotensin-converting enzyme gene polymorphism predicts the time-course of blood pressure response to angiotensin converting enzyme inhibition in the AASK trial by BHATNAGAR, Vibha, O'CONNOR, Daniel T, WRIGHT, Jackson T, CHEEK, Deanna, HIREMATH, Leena, CONTRERAS, Gabriel, APPEL, Lawrence J, LIPKOWITZ, Michael S, SCHORK, Nicholas J, SALEM, Rany M, NIEVERGELT, Caroline M, RANA, Brinda K, SMITH, Douglas W, BAKRIS, George L, MIDDLETON, John P, NORRIS, Keith C

“…It has yet to be determined whether genotyping at the angiotensin-converting enzyme (ACE) locus is predictive of blood pressure response to an ACE inhibitor…”
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Phylogenetic Analysis of the NEEP21/Calcyon/P19 Family of Endocytic Proteins: Evidence for Functional Evolution in the Vertebrate CNS by Muthusamy, Nagendran, Ahmed, Sanaa A, Rana, Brinda K, Navarre, Sammy, Kozlowski, David J, Liberles, David A, Bergson, Clare

“…Endocytosis and vesicle trafficking are required for optimal neural transmission. Yet, little is currently known about the evolution of neuronal proteins…”
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Functional allelic heterogeneity and pleiotropy of a repeat polymorphism in tyrosine hydroxylase: prediction of catecholamines and response to stress in twins by Zhang, Lian, Rao, Fangwen, Wessel, Jennifer, Kennedy, Brian P, Rana, Brinda K, Taupenot, Laurent, Lillie, Elizabeth O, Cockburn, Myles, Schork, Nicholas J, Ziegler, Michael G, O'Connor, Daniel T

“…1 Departments of Medicine, University of California at San Diego, San Diego, California 2 Psychiatry, University of California at San Diego, San Diego,…”
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Performance of the Self‐Report of the Effects of Alcohol Questionnaire Across Sexes and Generations by Schuckit, Marc A., Smith, Tom L., Rana, Brinda K., Mendoza, Lee Ann, Clarke, Dennis, Kawamura, Mari

“…Background Low level of responses (low LRs) to alcohol established using the Self‐Report of the Effects of Alcohol (SRE) questionnaire are genetically…”
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G protein-coupled receptor (GPCR) pharmacogenomics by Thompson, Miles D, Reiner-Link, David, Berghella, Alessandro, Rana, Brinda K, Rovati, G Enrico, Capra, Valerie, Gorvin, Caroline M, Hauser, Alexander S

“…The field of pharmacogenetics, the investigation of the influence of one or more sequence variants on drug response phenotypes, is a special case of…”
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