Search Results - "Rana, Ajay"

Transcription Factors in Cancer Development and Therapy by Vishnoi, Kanchan, Viswakarma, Navin, Rana, Ajay, Rana, Basabi

“…Cancer is a multi-step process and requires constitutive expression/activation of transcription factors (TFs) for growth and survival. Many of the TFs reported…”
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Correction: Expression and inactivation of glycogen synthase kinase 3 alpha/ beta and their association with the expression of cyclin D1 and p53 in oral squamous cell carcinoma progression by Mishra, Rajakishore, Nagini, Siddavaram, Rana, Ajay

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Phytotherapy with active tea constituents: a review by Rana, Ajay, Rana, Shalika, Kumar, Sanjay

“…Tea is a widely renowned functional beverage originating from processed tender leaves of the Camellia sinensis plant after brewing with hot water. This…”
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The Current Treatment Paradigm for Pancreatic Ductal Adenocarcinoma and Barriers to Therapeutic Efficacy by Principe, Daniel R, Underwood, Patrick W, Korc, Murray, Trevino, Jose G, Munshi, Hidayatullah G, Rana, Ajay

“…Pancreatic ductal adenocarcinoma (PDAC) has a dismal prognosis, with a median survival time of 10-12 months. Clinically, these poor outcomes are attributed to…”
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Canine distemper in Nepal's Annapurna Conservation Area - Implications of dog husbandry and human behaviour for wildlife disease by Ng, Debby, Carver, Scott, Gotame, Mukhiya, Karmasharya, Dibesh, Karmacharya, Dikpal, Man Pradhan, Saman, Narsingh Rana, Ajay, Johnson, Christopher N

“…Dogs are often commensal with human settlements. In areas where settlements are adjacent to wildlife habitat, the management of dogs can affect risk of…”
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Long-Term Gemcitabine Treatment Reshapes the Pancreatic Tumor Microenvironment and Sensitizes Murine Carcinoma to Combination Immunotherapy by Principe, Daniel R, Narbutis, Matthew, Kumar, Sandeep, Park, Alex, Viswakarma, Navin, Dorman, Matthew J, Kamath, Suneel D, Grippo, Paul J, Fishel, Melissa L, Hwang, Rosa F, Thummuri, Dinesh, Underwood, Patrick W, Munshi, Hidayatullah G, Trevino, Jose G, Rana, Ajay

“…Pancreatic ductal adenocarcinoma (PDAC) is a leading cause of cancer-related death with a median survival time of 6-12 months. Most patients present with…”
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Varietal influence on phenolic constituents and nutritive characteristics of pomace obtained from apples grown in western Himalayas by Rana, Shalika, Rana, Ajay, Gupta, Sakshi, Bhushan, Shashi

“…Apple fruit processing is not variety specific in India, which affect the overall quality of the final processed product. The present study was aimed at…”
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Population dynamics and genetic isolation in the Central Himalayan region: insights from Sikkim population, India by Priyank, Gaurav, Vahinde, Avinash, Niranjan, Penny H., Sahajpal, Vivek, Bhandari, Deepika, Rana, Ajay S., Kumar, Satish, Shukla, Malay, Nidhi, Sweta, Singh, Abhishek

“…India’s rich diversity encompasses individuals from varied geographical, cultural, and ethnic backgrounds. In the field of population genetics, comprehending…”
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Editorial: Diverse roles of MAP4K4 in MAP kinase signaling and its implication for cancer therapeutics by Roy, Ruchi, Singh, Sunil Kumar, Rana, Ajay

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Reviving the RNA World: An Insight into the Appearance of RNA Methyltransferases by Rana, Ajay K, Ankri, Serge

“…RNA, the earliest genetic and catalytic molecule, has a relatively delicate and labile chemical structure, when compared to DNA. It is prone to be damaged by…”
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MAP4K4 promotes pancreatic tumorigenesis via phosphorylation and activation of mixed lineage kinase 3 by Singh, Sunil Kumar, Kumar, Sandeep, Viswakarma, Navin, Principe, Daniel R., Das, Subhasis, Sondarva, Gautam, Nair, Rakesh Sathish, Srivastava, Piush, Sinha, Subhash C., Grippo, Paul J., Thatcher, Gregory R. J., Rana, Basabi, Rana, Ajay

“…MAP4K4 is a Ste20 member and reported to play important roles in various pathologies, including in cancer. However, the mechanism by which MAP4K4 promotes…”
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Alpha-synuclein induces lysosomal rupture and cathepsin dependent reactive oxygen species following endocytosis by Freeman, David, Cedillos, Rudy, Choyke, Samantha, Lukic, Zana, McGuire, Kathleen, Marvin, Shauna, Burrage, Andrew M, Sudholt, Stacey, Rana, Ajay, O'Connor, Christopher, Wiethoff, Christopher M, Campbell, Edward M

“…α-synuclein dysregulation is a critical aspect of Parkinson's disease pathology. Recent studies have observed that α-synuclein aggregates are cytotoxic to…”
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Involvement of AMP-activated protein kinase and Death Receptor 5 in TRAIL-Berberine-induced apoptosis of cancer cells by Ke, Rong, Vishnoi, Kanchan, Viswakarma, Navin, Santha, Sreevidya, Das, Subhasis, Rana, Ajay, Rana, Basabi

“…Our previous studies indicated that combination of Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) and PPARγ ligand Troglitazone (TZD), can…”
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Mixed lineage kinase 3 promotes breast tumorigenesis via phosphorylation and activation of p21-activated kinase 1 by Das, Subhasis, Nair, Rakesh Sathish, Mishra, Rajakishore, Sondarva, Gautam, Viswakarma, Navin, Abdelkarim, Hazem, Gaponenko, Vadim, Rana, Basabi, Rana, Ajay

“…Mixed lineage kinase 3 (MLK3), a MAP3K member has been envisioned as a viable drug target in cancer, yet its detailed function and signaling is not fully…”
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Ets1 mediates sorafenib resistance by regulating mitochondrial ROS pathway in hepatocellular carcinoma by Vishnoi, Kanchan, Ke, Rong, Viswakarma, Navin, Srivastava, Piush, Kumar, Sandeep, Das, Subhasis, Singh, Sunil Kumar, Principe, Daniel R., Rana, Ajay, Rana, Basabi

“…The incidence and mortality of hepatocellular carcinoma (HCC) are on a rise in the Western countries including US, attributed mostly to late detection…”
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Parametric optimization of curved-rectangular shaped magnetorheological finishing tool for external cylindrical surfaces by Rana, Ajay Singh, Rafiq, Iqra, Bedi, Talwinder Singh

“…Finishing of cylindrical surfaces in nano-scale roughness level is important to improve the surface structure of various industrial components. The…”
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Mitogen-Activated Protein Kinase Inhibitors and T-Cell-Dependent Immunotherapy in Cancer by Kumar, Sandeep, Principe, Daniel R, Singh, Sunil Kumar, Viswakarma, Navin, Sondarva, Gautam, Rana, Basabi, Rana, Ajay

“…Mitogen-activated protein kinase (MAPK) signaling networks serve to regulate a wide range of physiologic and cancer-associated cell processes. For instance, a…”
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Loss of SMAD4 Is Associated With Poor Tumor Immunogenicity and Reduced PD-L1 Expression in Pancreatic Cancer by Principe, Daniel R, Underwood, Patrick W, Kumar, Sandeep, Timbers, Kaytlin E, Koch, Regina M, Trevino, Jose G, Munshi, Hidayatullah G, Rana, Ajay

“…Transforming Growth Factor β (TGFβ) is a key mediator of immune evasion in pancreatic ductal adenocarcinoma (PDAC), and the addition of TGFβ inhibitors in…”
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Correction: Mixed lineage kinase 3 promotes breast tumorigenesis via phosphorylation and activation of p21-activated kinase 1 by Das, Subhasis, Nair, Rakesh Sathish, Mishra, Rajakishore, Sondarva, Gautam, Viswakarma, Navin, Abdelkarim, Hazem, Gaponenko, Vadim, Sathyanarayana, Pradeep, Rana, Basabi, Rana, Ajay

“…The original version of this Article did not acknowledge Pradeep Sathyanarayana as an author. His affiliation is Center for Molecular Medicine, Maine Medical…”
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HAI-1 is an independent predictor of lung cancer mortality and is required for M1 macrophage polarization by Borowicz, Stanley, Principe, Daniel R, Dorman, Matthew J, McHenry, Austin J, Sondarva, Gautam, Kumar, Sandeep, Ananthanarayanan, Vijayalakshmi, Simms, Patricia E, Hess, Ashley, Rana, Ajay

“…Non-small cell lung cancer (NSCLC) is the leading cause of cancer-related death worldwide. Though immune checkpoint inhibitors (ICIs) have revolutionized lung…”
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