Search Results - "Ramu, Ravirala"

A Carbon Electrode Functionalized by a Tricopper Cluster Complex: Overcoming Overpotential and Production of Hydrogen Peroxide in the Oxygen Reduction Reaction by Thiyagarajan, Natarajan, Janmanchi, Damodar, Tsai, Yi‐Fang, Wanna, Wondemagegn Hailemichael, Ramu, Ravirala, Chan, Sunney I., Zen, Jyh‐Myng, Yu, Steve S.‐F.

“…A study of the oxygen reduction reaction (ORR) on a screen printed carbon electrode surface mediated by the tricopper cluster complex Cu3(7‐N‐Etppz(CH2OH))…”
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Electrochemical Hydroxylation of C3–C12 n-Alkanes by Recombinant Alkane Hydroxylase (AlkB) and Rubredoxin-2 (AlkG) from Pseudomonas putida GPo1 by Tsai, Yi-Fang, Luo, Wen-I, Chang, Jen-Lin, Chang, Chun-Wei, Chuang, Huai-Chun, Ramu, Ravirala, Wei, Guor-Tzo, Zen, Jyh-Myng, Yu, Steve S.-F.

“…Abstract An unprecedented method for the efficient conversion of C 3 –C 12 linear alkanes to their corresponding primary alcohols mediated by the…”
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Selective Oxidation of Simple Aromatics Catalyzed by Nano-Biomimetic Metal Oxide Catalysts: A Mini Review by Wanna, Wondemagegn H, Janmanchi, Damodar, Thiyagarajan, Natarajan, Ramu, Ravirala, Tsai, Yi-Fang, Yu, Steve S F

“…The process of selective oxy-functionalization of hydrocarbons using peroxide, O , H O , O , and transition metals can be carried out by the reactive oxygen…”
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Mechanistic Study of the Stereoselective Hydroxylation of [2‐2H1,3‐2H1]Butanes Catalyzed by Cytochrome P450 BM3 Variants by Yang, Chung‐Ling, Lin, Cheng‐Hung, Luo, Wen‐I, Lee, Tsu‐Lin, Ramu, Ravirala, Ng, Kok Yaoh, Tsai, Yi‐Fang, Wei, Guor‐Tzo, Yu, Steve S.‐F.

“…Engineered bacterial cytochrome P450s are noted for their ability in the oxidation of inert small alkanes. Cytochrome P450 BM3 L188P A328F (BM3 PF) and A74E…”
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An Efficient One-Pot Synthesis of Polyhydroquinolines at Room Temperature Using HY-Zeolite by Das, Biswanath, Ravikanth, Bommena, Ramu, Ravirala, Rao, Bommena Vittal

“…An efficient one-pot synthesis of polyhydroquinolines by four-component coupling reactions of aldehydes, ethyl acetoacetate, dimedone and ammonium acetate in…”
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Mechanistic study for the selective oxidation of benzene and toluene catalyzed by Fe(ClO4)2 in an H2O2-H2O-CH3CN system by Ramu, Ravirala, Wanna, Wondemagegn Hailemichael, Janmanchi, Damodar, Tsai, Yi-Fang, Liu, Chih-Cheng, Mou, Chung-Yuan, Yu, Steve S.-F.

“…[Display omitted] •Fe-catalyzed oxidation of aromatics in a H2O2-H2O-CH3CN system is developed.•Products of benzene oxidation yield controllable ratios of PhOH…”
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New Lathyrane and Podocarpane Diterpenoids from Jatropha curcas by Ravindranath, Nasi, Reddy, Majjigapu Ravinder, Ramesh, Chimmani, Ramu, Ravirala, Prabhakar, Anabathula, Jagadeesh, Bharatam, Das, Biswanath

“…Chemical investigation on Jatropha curcas resulted in the isolation of twenty constituents among which four diterpenoids were unknown and six compounds,…”
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Design, Structure–Activity Relationships, and In Vivo Evaluation of Potent and Brain-Penetrant Imidazo[1,2‑b]pyridazines as Glycogen Synthase Kinase-3β (GSK-3β) Inhibitors by Hartz, Richard A., Ahuja, Vijay T., Sivaprakasam, Prasanna, Xiao, Hong, Krause, Carol M., Clarke, Wendy J., Kish, Kevin, Lewis, Hal, Szapiel, Nicolas, Ravirala, Ramu, Mutalik, Sayali, Nakmode, Deepa, Shah, Devang, Burton, Catherine R., Macor, John E., Dubowchik, Gene M.

“…Glycogen synthase kinase-3 (GSK-3) is a serine/threonine kinase that regulates numerous cellular processes, including metabolism, proliferation, and cell…”
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An efficient and recyclable copper nano-catalyst for the selective oxidation of benzene to p-benzoquinone (p-BQ) using H2O2(aq) in CH3CN by Wanna, Wondemagegn Hailemichael, Ramu, Ravirala, Janmanchi, Damodar, Tsai, Yi-Fang, Thiyagarajan, Natarajan, Yu, Steve S.-F.

“…Copper nano-catalyst accumulated from [Cu(CH3CN)4ClO4] in a reaction mixture of H2O2(aq) and CH3CN can efficiently catalyze the conversion of benzene to…”
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Discovery of 2‑(Anilino)pyrimidine-4-carboxamides as Highly Potent, Selective, and Orally Active Glycogen Synthase Kinase‑3 (GSK-3) Inhibitors by Hartz, Richard A., Ahuja, Vijay T., Luo, Guanglin, Chen, Ling, Sivaprakasam, Prasanna, Xiao, Hong, Krause, Carol M., Clarke, Wendy J., Xu, Songmei, Tokarski, John S., Kish, Kevin, Lewis, Hal, Szapiel, Nicolas, Ravirala, Ramu, Mutalik, Sayali, Nakmode, Deepa, Shah, Devang, Burton, Catherine R., Macor, John E., Dubowchik, Gene M.

“…Glycogen synthase kinase-3 (GSK-3) is a serine/threonine kinase that serves as an important regulator of a broad range of cellular functions. It has been…”
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Abstract 677: Discovery of a first-in-class allosteric inhibitor of the small GTPase Rac1 by Silverman, Robert, Cooper, Alan, Kar, Ronodip, Raman, Mayuri V., Ravirala, Ramu, Shah, Mubarak Hasan, Mahankali, Sandeep, Goka, Erik T.

“…Abstract The Rac1 signaling pathway is known to be hyperactivated in numerous solid tumors. We developed a Rac1 AlphaLISA assay that is amenable to…”
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Natural flavonoids silymarin and quercetin improve the brain distribution of co-administered P-gp substrate drugs by Ravikumar Reddy, D., Khurana, Amit, Bale, Swarna, Ravirala, Ramu, Samba Siva Reddy, V., Mohankumar, M., Godugu, Chandraiah

“…P-glycoprotein (P-gp), a well known efflux transporter in the blood brain barrier inhibits the uptake of substrate drugs into brain. The main aim of this study…”
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Frontispiece: Mechanistic Study of the Stereoselective Hydroxylation of [2‐2H1,3‐2H1]Butanes Catalyzed by Cytochrome P450 BM3 Variants by Yang, Chung‐Ling, Lin, Cheng‐Hung, Luo, Wen‐I, Lee, Tsu‐Lin, Ramu, Ravirala, Ng, Kok Yaoh, Tsai, Yi‐Fang, Wei, Guor‐Tzo, Yu, Steve S.‐F.

“…Catalytic mechanism of cytochrome P450 A high H/D kinetic isotope effect (KIE) (18–25) is observed from the hydroxylation of tailored di‐deuterated butane…”
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Regioselective Hydroxylation of C 12 –C 15 Fatty Acids with Fluorinated Substituents by Cytochrome P450 BM3 by Chiang, Chih‐Hsiang, Ramu, Ravirala, Tu, Yi‐Jung, Yang, Chung‐Ling, Ng, Kok Yaoh, Luo, Wen‐I, Chen, Charles H., Lu, Yu‐Ying, Liu, Chen‐Lun, Yu, Steve S.‐F.

“…Abstract We demonstrate herein that wild‐type cytochrome P450 BM3 can recognize non‐natural substrates, such as fluorinated C 12 –C 15 chain‐length fatty…”
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Regioselective Hydroxylation of C12-C15 Fatty Acids with Fluorinated Substituents by Cytochrome P450 BM3 by Chiang, Chih-Hsiang, Ramu, Ravirala, Tu, Yi-Jung, Yang, Chung-Ling, Ng, Kok Yaoh, Luo, Wen-I, Chen, Charles H., Lu, Yu-Ying, Liu, Chen-Lun, Yu, Steve S.-F.

“…We demonstrate herein that wild‐type cytochrome P450 BM3 can recognize non‐natural substrates, such as fluorinated C12–C15 chain‐length fatty acids, and show…”
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Corrigendum to “Regio-selective hydroxylation of gem-difluorinated octanes by alkane hydroxylase (AlkB)” [Tetrahedron Lett. 52(23) (2011) 2950–2953] by Ramu, Ravirala, Chang, Chun-Wei, Chou, Ho-Hsuan, Wu, Li-Lan, Chiang, Chih-Hsiang, Yu, Steve S.-F.

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Fenofibrate but not fenofibric acid inhibits 11beta-hydroxysteroid dehydrogenase 1 in C2C12 myotubes by Kim, Chi Hyun, Ramu, Ravirala, Ahn, Jin Hee, Bae, Myung Ae, Cho, Young Sik

“…Fibrates and WY-14643 are widely used as lipid-lowering drugs via modulation of peroxisome proliferator-activated receptor alpha (PPAR α) for the treatment of…”
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Regio‐ and stereo‐selective oxidation of fluorinated substrates by recombinant cytochrome P450 BM3 variants by Yu, Steve S.‐F., Wu, Li‐Lan, Chiang, Chih‐Hsiang, Ramu, Ravirala, Yang, Chung‐Ling, Ng, Kok Yaoh, Luo, Wen‐I, Chan, Sunney I.

“…Abstract only We recently showed that, upon the addition of fluorine substituents on n‐octane, van der Waals interactions including dispersion between a ‐CF 2…”
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Regioselective Hydroxylation of C12-C15 Fatty Acids with Fluorinated Substituents by CytochromeP450 BM3 by Chiang, Chih-Hsiang, Ramu, Ravirala, Tu, Yi-Jung, Yang, Chung-Ling, Ng, Kok Yaoh, Luo, Wen-I, Chen, Charles H, Lu, Yu-Ying, Liu, Chen-Lun, Yu, Steve S-F

“…We demonstrate herein that wild-type cytochromeP450 BM3 can recognize non-natural substrates, such as fluorinated C12-C15 chain-length fatty acids, and show…”
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Regioselective Hydroxylation of C sub(12)-C sub(15) Fatty Acids with Fluorinated Substituents by CytochromeP450 BM3 by Chiang, Chih-Hsiang, Ramu, Ravirala, Tu, Yi-Jung, Yang, Chung-Ling, Ng, Kok Yaoh, Luo, Wen-I, Chen, Charles H, Lu, Yu-Ying, Liu, Chen-Lun, Yu, Steve S-F

“…We demonstrate herein that wild-type cytochromeP450 BM3 can recognize non-natural substrates, such as fluorinated C sub(12)-C sub(15) chain-length fatty acids,…”
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