Search Results - "Ramsey, Manda J."

Mechanistic studies of PEG-asparaginase-induced liver injury and hepatic steatosis in mice by Kumar, Gundala Venkata Naveen, Hoshitsuki, Keito, Rathod, Sanjay, Ramsey, Manda J., Kokai, Lauren, Kershaw, Erin E., Xie, Wen, Fernandez, Christian A.

“…PEGylated-l-asparaginase (PEG-ASNase) is a chemotherapeutic agent used to treat pediatric acute lymphoblastic leukemia (ALL). Its use is avoided in adults due…”
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Adalimumab Immunogenicity Is Negatively Correlated with Anti-Hinge Antibody Levels in Patients with Rheumatoid Arthritis by Hoshitsuki, Keito, Rathod, Sanjay, Ramsey, Manda J, Zhu, Lei, Moreland, Larry W, Fernandez, Christian A

“…Patients with rheumatoid arthritis (RA) are frequently treated with anti-tumor necrosis factor- immunoglobulin therapy but develop neutralizing antibodies…”
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Overexpression of AMPKγ2 increases AMPK signaling to augment human T cell metabolism and function by Braverman, Erica L, McQuaid, Margaret A, Schuler, Herbert, Qin, Mengtao, Hani, Sophia, Hippen, Keli, Monlish, Darlene A, Dobbs, Andrea K, Ramsey, Manda J, Kemp, Felicia, Wittmann, Christopher, Ramgopal, Archana, Brown, Harrison, Blazar, Bruce, Byersdorfer, Craig A

“…Cellular therapies are currently employed to treat a variety of disease processes. For T cell-based therapies, success often relies on the metabolic fitness of…”
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AMPK drives both glycolytic and oxidative metabolism in murine and human T cells during graft-versus-host disease by Ramgopal, Archana, Braverman, Erica L., Sun, Lee-Kai, Monlish, Darlene, Wittmann, Christopher, Kemp, Felicia, Qin, Mengtao, Ramsey, Manda J., Cattley, Richard, Hawse, William, Byersdorfer, Craig A.

“…•AMPK plays a key role in driving both and oxidative and glycolytic metabolism in T cells during GVHD.•Absence of AMPK simultaneously impairs both glycolytic…”
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PEG‐asparaginase‐induced hepatic steatosis is associated with PKA activation and white adipose tissue lipolysis by Kumar, Gundala Venkata Naveen, Ramsey, Manda J., Rathod, Sanjay, Fernandez, Christian

“…Background PEGylated L‐asparaginase (PEG‐ASNase) is an essential chemotherapeutic agent used in the treatment of pediatric acute lymphoblastic leukemia (ALL)…”
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