Search Results - "Ramsey, Deborah M."

Understanding the control of Pseudomonas aeruginosa alginate synthesis and the prospects for management of chronic infections in cystic fibrosis by Ramsey, Deborah M., Wozniak, Daniel J.

“…Summary Decades of research have been dedicated to the study of the opportunistic pathogen Pseudomonas aeruginosa, a Gram‐negative, environmental bacterium…”
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The Pseudomonas aeruginosa Ribbon-Helix-Helix DNA-Binding Protein AlgZ (AmrZ) Controls Twitching Motility and Biogenesis of Type IV Pili by BAYNHAM, Patricia J, RAMSEY, Deborah M, GVOZDYEV, Borys V, CORDONNIER, Ellen M, WOZNIAK, Daniel J

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AmrZ Beta-Sheet Residues Are Essential for DNA Binding and Transcriptional Control of Pseudomonas aeruginosa Virulence Genes by Waligora, Elizabeth A, Ramsey, Deborah M, Pryor, Jr, Edward E, Lu, Haiping, Hollis, Thomas, Sloan, Gina P, Deora, Rajendar, Wozniak, Daniel J

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Halting metastasis through CXCR4 inhibition by Ramsey, Deborah M., McAlpine, Shelli R.

“…Metastasis occurs when cancer cells leave the primary tumor site and migrate to distant parts of the body. The CXCR4–SDF-1 pathway facilitates this migration,…”
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Binding of Pseudomonas aeruginosa AlgZ to Sites Upstream of the algZ Promoter Leads to Repression of Transcription by RAMSEY, Deborah M, BAYNHAM, Patricia J, WOZNIAK, Daniel J

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Total Synthesis of trans,trans-Sanguinamide B and Conformational Isomers by Singh, Erinprit K, Ramsey, Deborah M, McAlpine, Shelli R

“…The first total synthesis of Sanguinamide B is reported, prepared via an efficient synthetic strategy. The natural product, trans,trans-Sanguinamide B (1), was…”
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Mechanistic Studies of Sanguinamide B Derivatives: A Unique Inhibitor of Eukaryotic Ribosomes by Tantisantisom, Worawan, Ramsey, Deborah M, McAlpine, Shelli R

“…Described are mechanistic studies of two Sanguinamide B (San B) derivatives. These compounds were identified as eukaryotic ribosomal inhibitors. Two…”
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Synthesis, Structure–Activity Analysis, and Biological Evaluation of Sanguinamide B Analogues by Wahyudi, Hendra, Tantisantisom, Worawan, Liu, Xuechao, Ramsey, Deborah M, Singh, Erinprit K, McAlpine, Shelli R

“…We report the first synthesis of sanguinamide B analogues. Substituting N-methylated (N-Me) amino acids, glycine (Gly), and l- or d-phenylalanine (Phe) into…”
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A potential rhodium cancer therapy: Studies of a cytotoxic organorhodium(I) complex that binds DNA by McConnell, Jeanette R., Rananaware, Dimple P, Ramsey, Deborah M., Buys, Kai N., Cole, Marcus L., McAlpine, Shelli R.

“…Described is a novel organorhodium(I) complex that is cytotoxic to the colon cancer cell line HCT116 and alters cell migration, DNA replication, and DNA…”
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Simultaneous bone marrow and composite tissue transplantation in rats treated with nonmyeloablative conditioning promotes tolerance by Xu, Hong, Ramsey, Deborah M, Wu, Shengli, Bozulic, Larry D, Ildstad, Suzanne T

“…Approaches to safely induce tolerance in vascularized composite allotransplantation (VCA) with chimerism through bone marrow transplantation (BMT) are…”
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Effectively Delivering a Unique Hsp90 Inhibitor Using Star Polymers by Kim, Seong Jong, Ramsey, Deborah M, Boyer, Cyrille, Davis, Thomas P, McAlpine, Shelli R

“…We report the synthesis of a novel heat shock protein 90 (hsp90) inhibitor conjugated to a star polymer. Using reversible addition–fragmentation chain-transfer…”
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Psammaplysin F: A unique inhibitor of bacterial chromosomal partitioning by Ramsey, Deborah M., Amirul Islam, Md, Turnbull, Lynne, Davis, Rohan A., Whitchurch, Cynthia B., McAlpine, Shelli R.

“…Described is the antibiotic activity of a marine natural product. Psammaplysin F (1) inhibited the growth of four Gram-positive strains by >80% at 50μM, and…”
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An Hsp90 modulator that exhibits a unique mechanistic profile by Ramsey, Deborah M., McConnell, Jeanette R., Alexander, Leslie D., Tanaka, Kaishin W., Vera, Chester M., McAlpine, Shelli R.

“…Described is the synthesis of two biotinylated derivatives of a cytotoxic macrocycle. Pull-down assays indicate that this macrocycle targets the N-middle…”
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Pseudomonas aeruginosa AmrZ C‐terminal domain mediates tetramerization and is required for its activator and repressor functions by Xu, Binjie, Ju, Yue, Soukup, Randal J, Ramsey, Deborah M, Fishel, Richard, Wysocki, Vicki H, Wozniak, Daniel J

“…Pseudomonas aeruginosa is an important bacterial opportunistic pathogen, presenting a significant threat towards individuals with underlying diseases such as…”
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Simultaneous bone marrow and composite tissue transplantation in rats treated with nonmyeloablative conditioning promotes tolerance1 by Xu, Hong, Ramsey, Deborah M., Wu, Shengli, Bozulic, Larry D., Ildstad, Suzanne T.

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The P seudomonas aeruginosa   AmrZ C ‐terminal domain mediates tetramerization and is required for its activator and repressor functions by Xu, Binjie, Ju, Yue, Soukup, Randal J., Ramsey, Deborah M., Fishel, Richard, Wysocki, Vicki H., Wozniak, Daniel J.

“…P seudomonas aeruginosa is an important bacterial opportunistic pathogen, presenting a significant threat towards individuals with underlying diseases such as…”
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Human CD8+/TCR−/CD56dim/− facilitating Cells Enhance Engraftment of HSC In NOD/SCID/IL2rγnull Recipients by Huang, Yiming, Elliott, Mary J, Ramsey, Deborah M, Miller, Thomas, Bozulic, Larry D, Ocker, Ashley A, King, Bradley J, Ildstad, Suzanne T.

“…Abstract 3709 CD8+/TCR− graft facilitating cells (FC) enhance engraftment of hematopoietic stem cells (HSC). They are distinct from HSC since they do not…”
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Simultaneous bone marrow and tissue transplantation in rats treated with a nonmyeloablative conditioning regimen promote tolerance to composite tissue allografts (141.18) by Ramsey, Deborah M., Bozulic, Larry D., Wu, Shengli, Adamson, Larry A., Rahhal, Dina N., Swearingen, Bruce J., Xu, Hong, Ildstad, Suzanne T.

“…Approaches to safely induce graft acceptance through bone marrow chimerism and limited immunosuppression are currently being pursued. Here we evaluated the…”
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