Search Results - "Ramsden, Jeremy"

Data evaluation for surface-sensitive label-free methods to obtain real-time kinetic and structural information of thin films: A practical review with related software packages by Saftics, Andras, Kurunczi, Sándor, Peter, Beatrix, Szekacs, Inna, Ramsden, Jeremy J., Horvath, Robert

“…Interfacial layers are important in a wide range of applications in biomedicine, biosensing, analytical chemistry and the maritime industries. Given the…”
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Imine reductases (IREDs) by Mangas-Sanchez, Juan, France, Scott P, Montgomery, Sarah L, Aleku, Godwin A, Man, Henry, Sharma, Mahima, Ramsden, Jeremy I, Grogan, Gideon, Turner, Nicholas J

“…•Imine reductases (IREDs) enable the asymmetric synthesis of amines from imines.•The development of annotated sequence databases has led to the discovery of…”
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Biocatalytic N‑Alkylation of Amines Using Either Primary Alcohols or Carboxylic Acids via Reductive Aminase Cascades by Ramsden, Jeremy I, Heath, Rachel S, Derrington, Sasha R, Montgomery, Sarah L, Mangas-Sanchez, Juan, Mulholland, Keith R, Turner, Nicholas J

“…The alkylation of amines with either alcohols or carboxylic acids represents a mild and safe alternative to the use of genotoxic alkyl halides and sulfonate…”
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Asymmetric synthesis of primary amines catalyzed by thermotolerant fungal reductive aminases by Mangas-Sanchez, Juan, Sharma, Mahima, Cosgrove, Sebastian C, Ramsden, Jeremy I, Marshall, James R, Thorpe, Thomas W, Palmer, Ryan B, Grogan, Gideon, Turner, Nicholas J

“…Chiral primary amines are important intermediates in the synthesis of pharmaceutical compounds. Fungal reductive aminases (RedAms) are NADPH-dependent…”
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Is it time for biocatalysis in fragment-based drug discovery? by Ramsden, Jeremy I, Cosgrove, Sebastian C, Turner, Nicholas J

“…The use of biocatalysts for fragment-based drug discovery has yet to be fully investigated, despite the promise enzymes hold for the synthesis of…”
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A Mechanism for Reductive Amination Catalyzed by Fungal Reductive Aminases by Sharma, Mahima, Mangas-Sanchez, Juan, France, Scott P, Aleku, Godwin A, Montgomery, Sarah L, Ramsden, Jeremy I, Turner, Nicholas J, Grogan, Gideon

“…Reductive aminases (RedAms) catalyze the asymmetric reductive amination of ketones with primary amines to give secondary amine products. RedAms have great…”
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Dependence of cancer cell adhesion kinetics on integrin ligand surface density measured by a high-throughput label-free resonant waveguide grating biosensor by Orgovan, Norbert, Peter, Beatrix, Bősze, Szilvia, Ramsden, Jeremy J., Szabó, Bálint, Horvath, Robert

“…A novel high-throughput label-free resonant waveguide grating (RWG) imager biosensor, the Epic® BenchTop (BT), was utilized to determine the dependence of cell…”
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Natural heterogeneous catalysis with immobilised oxidase biocatalysts by Mattey, Ashley P, Sangster, Jack J, Ramsden, Jeremy I, Baldwin, Christopher, Birmingham, William R, Heath, Rachel S, Angelastro, Antonio, Turner, Nicholas J, Cosgrove, Sebastian C, Flitsch, Sabine L

“…The generation of immobilised oxidase biocatalysts allowing multifunctional oxidation of valuable chemicals using molecular oxygen is described. Engineered…”
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Optical Anisotropy of Flagellin Layers: In Situ and Label-Free Measurement of Adsorbed Protein Orientation Using OWLS by Kovacs, Noemi, Patko, Daniel, Orgovan, Norbert, Kurunczi, Sandor, Ramsden, Jeremy J, Vonderviszt, Ferenc, Horvath, Robert

“…The surface adsorption of the protein flagellin was followed in situ using optical waveguide lightmode spectroscopy (OWLS). Flagellin did not show significant…”
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How Does a Photocatalytic Antimicrobial Coating Affect Environmental Bioburden in Hospitals? by Reid, Matthew, Whatley, Vanessa, Spooner, Emma, Nevill, Alan M, Cooper, Michael, Ramsden, Jeremy J, Dancer, Stephanie J

“…BACKGROUND The healthcare environment is recognized as a source for healthcare-acquired infection. Because cleaning practices are often erratic and always…”
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Staphylococcus aureus resists UVA at low irradiance but succumbs in the presence of TiO 2 photocatalytic coatings by Clemente, Andrea, Ramsden, Jeremy J, Wright, Alec, Iza, Felipe, Morrissey, Julie A, Li Puma, Gianluca, Malik, Danish J

“…The aim of this study was to evaluate the bactericidal effect of reactive oxygen species (ROS) generated upon irradiation of photocatalytic TiO surface…”
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Viscous Boundary Lubrication of Hydrophobic Surfaces by Mucin by Yakubov, Gleb E, McColl, James, Bongaerts, Jeroen H. H, Ramsden, Jeremy J

“…The lubricating behavior of the weakly charged short-side-chain glycoprotein mucin “Orthana” (M w = 0.55 MDa) has been investigated between hydrophobic and…”
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Bifunctional Imine Reductase Cascades for the Synthesis of Saturated N‑Heterocycles by Ramsden, Jeremy I., Zucoloto da Costa, Bruna, Heath, Rachel S., Marshall, James R., Derrington, Sasha R., Mangas-Sanchez, Juan, Montgomery, Sarah L., Mulholland, Keith R., Cosgrove, Sebastian C., Turner, Nicholas J.

“…Saturated N-heterocycles constitute a vital scaffold for pharmaceutical chemistry but are challenging to access synthetically, particularly asymmetrically…”
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Questioning the catalytic effect of Ni nanoparticles on CO2 hydration and the very need of such catalysis for CO2 capture by mineralization from aqueous solution by Ramsden, Jeremy J., Sokolov, Ilya J., Malik, Danish J.

“…•Numerical simulation of carbonation reactions for CaCO3 production from CO2.•Production of protons limits the equilibrium CO32− concentration which remains…”
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The impact of zero-valent iron nanoparticles upon soil microbial communities is context dependent by Pawlett, Mark, Ritz, Karl, Dorey, Robert A., Rocks, Sophie, Ramsden, Jeremy, Harris, Jim A.

“…Nanosized zero-valent iron (nZVI) is an effective land remediation tool, but there remains little information regarding its impact upon and interactions with…”
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Review of Label-Free Monitoring of Bacteria: From Challenging Practical Applications to Basic Research Perspectives by Péter, Beatrix, Farkas, Eniko, Kurunczi, Sandor, Szittner, Zoltán, Bősze, Szilvia, Ramsden, Jeremy J, Szekacs, Inna, Horvath, Robert

“…Novel biosensors already provide a fast way to detect the adhesion of whole bacteria (or parts of them), biofilm formation, and the effect of antibiotics…”
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Sample handling in surface sensitive chemical and biological sensing: A practical review of basic fluidics and analyte transport by Orgovan, Norbert, Patko, Daniel, Hos, Csaba, Kurunczi, Sándor, Szabó, Bálint, Ramsden, Jeremy J., Horvath, Robert

“…This paper gives an overview of the advantages and associated caveats of the most common sample handling methods in surface-sensitive chemical and biological…”
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Staphylococcus aureus resists UVA at low irradiance but succumbs in the presence of TiO2 photocatalytic coatings by Clemente, Andrea, Ramsden, Jeremy J., Wright, Alec, Iza, Felipe, Morrissey, Julie A., Li Puma, Gianluca, Malik, Danish J.

“…The aim of this study was to evaluate the bactericidal effect of reactive oxygen species (ROS) generated upon irradiation of photocatalytic TiO2 surface…”
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Redox surrogate methods for sustainable amine N-alkylation by Ruscoe, Rebecca E, Ramsden, Jeremy I, Turner, Nicholas J

“…The N-alkylation of amines constitutes one of the most widely applied transformations in synthetic chemistry, but established methods often utilise…”
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Citrullinated isomer of myelin basic protein can induce inflammatory responses in astrocytes by Chikviladze, Marika, Mamulashvili, Nino, Sepashvili, Maia, Narmania, Nana, Ramsden, Jeremy, Shanshiashvili, Lali, Mikeladze, David

“…During the course of demyelinating inflammatory diseases, myelin-derived proteins, including myelin basic protein(MBP), are secreted into extracellular space…”
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