Search Results - "Ramsdell, Ann F"

Left–right asymmetry and congenital cardiac defects: Getting to the heart of the matter in vertebrate left–right axis determination by Ramsdell, Ann F.

“…Cellular and molecular left–right differences that are present in the mesodermal heart fields suggest that the heart is lateralized from its inception…”
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Introduction to provocative questions in left–right asymmetry by Levin, Michael, Klar, Amar J. S., Ramsdell, Ann F.

“…Left–right asymmetry is a phenomenon that has a broad appeal—to anatomists, developmental biologists and evolutionary biologists—because it is a morphological…”
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Left-right lineage analysis of the embryonic Xenopus heart reveals a novel framework linking congenital cardiac defects and laterality disease by Ramsdell, Ann F, Bernanke, Jayne M, Trusk, Thomas C

“…The significant morbidity and mortality associated with laterality disease almost always are attributed to complex congenital heart defects (CHDs), reflecting…”
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Positional Variations in Mammary Gland Development and Cancer by Veltmaat, Jacqueline M., Ramsdell, Ann F., Sterneck, Esta

“…Most mammals develop their mammary glands in pairs of which the two counterparts are symmetrically displaced away from the ventral midline. Based on this…”
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Intraductal Adaptation of the 4T1 Mouse Model of Breast Cancer Reveals Effects of the Epithelial Microenvironment on Tumor Progression and Metastasis by Atiya, Huda I, Dvorkin-Gheva, Anna, Hassell, John, Patel, Shrusti, Parker, Rachel L, Hartstone-Rose, Adam, Hodge, Johnie, Fan, Daping, Ramsdell, Ann F

“…Low success rates in oncology drug development are prompting re-evaluation of preclinical models, including orthotopic tumor engraftment. In breast cancer…”
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Inhibition of heart formation by lithium is an indirect result of the disruption of tissue organization within the embryo by Martin, Lisa K., Bratoeva, Momka, Mezentseva, Nadejda V., Bernanke, Jayne M., Remond, Mathieu C., Ramsdell, Ann F., Eisenberg, Carol A., Eisenberg, Leonard M.

“…Lithium is a commonly used drug for the treatment of bipolar disorder. At high doses, lithium becomes teratogenic, which is a property that has allowed this…”
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Left–right analysis of mammary gland development in retinoid X receptor-α+/− mice by Robichaux, Jacqulyne P., Fuseler, John W., Patel, Shrusti S., Kubalak, Steven W., Hartstone-Rose, Adam, Ramsdell, Ann F.

“…Left–right (L–R) differences in mammographic parenchymal patterns are an early predictor of breast cancer risk; however, the basis for this asymmetry is…”
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Morphometric and fractal dimension analysis identifies early neoplastic changes in mammary epithelium of MMTV-cNeu mice by Fuseler, John W, Robichaux, Jacqulyne P, Atiyah, Huda I, Ramsdell, Ann F

“…Fractal dimension has emerged as a clinically useful tool in the diagnosis and management of breast cancer. The aim of the present study was to determine if…”
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Canonical WNT signaling enhances stem cell expression in the developing heart without a corresponding inhibition of cardiogenic differentiation by Martin, Lisa K, Mezentseva, Nadejda V, Bratoeva, Momka, Ramsdell, Ann F, Eisenberg, Carol A, Eisenberg, Leonard M

“…WNT signaling has been shown to influence the development of the heart. Although recent data suggested that canonical WNTs promote the emergence and expansion…”
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Developmental toxicity of domoic acid in zebrafish ( Danio rerio) by Tiedeken, Jessica A., Ramsdell, John S., Ramsdell, Ann F.

“…Domoic acid (DA) is a rigid analog of the excitatory amino acid glutamate. It is produced by the diatom genus Pseudo-nitzschia and is a potent neurotoxin in…”
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Molecular mechanisms of vertebrate left–right development by Ramsdell, Ann F, Yost, H.Joseph

“…Patterning of all tissues and organs in the vertebrate embryo occurs along the dorsoventral (DV), anteroposterior (AP), and left–right (LR) body axes. Whereas…”
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ALK4 functions as a receptor for multiple TGFβ-related ligands to regulate left–right axis determination and mesoderm induction in Xenopus by Chen, Yumei, Mironova, Ekaterina, Whitaker, Lisha L, Edwards, Laura, Yost, H.Joseph, Ramsdell, Ann F

“…In Xenopus, several TGFβs, including nodal-related 1 (Xnr1), derriere, and chimeric forms of Vg1, elicit cardiac and visceral organ left–right (LR) defects…”
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Developmental analysis of activin‐like kinase receptor‐4 (ALK4) expression in Xenopus laevis by Chen, Yumei, Whitaker, Lisha L., Ramsdell, Ann F.

“…The type I transforming growth factor‐beta (TGFβ) receptor, activin‐like kinase‐4 (ALK4), is an important regulator of vertebrate development, with roles in…”
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Introduction: Introduction to provocative questions in left–right asymmetry by Levin, Michael, Klar, Amar J. S., Ramsdell, Ann F.

“…Left–right asymmetry is a phenomenon that has a broad appeal—to anatomists, developmental biologists and evolutionary biologists—because it is a morphological…”
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Left‐right lineage analysis of AV cushion tissue in normal and laterality defective Xenopus hearts by Ramsdell, Ann F., Bernanke, Jayne M., Johnson, John, Trusk, Thomas C.

“…The majority of complex congenital heart defects occur in individuals who are afflicted by laterality disease. We hypothesize that the prevalence of…”
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Left–right analysis of mammary gland development in retinoid X receptor-α+/−mice by Robichaux, Jacqulyne P., Fuseler, John W., Patel, Shrusti S., Kubalak, Steven W., Hartstone-Rose, Adam, Ramsdell, Ann F.

“…Left–right (L–R) differences in mammographic parenchymal patterns are an early predictor of breast cancer risk; however, the basis for this asymmetry is…”
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Mammary glands exhibit molecular laterality and undergo left–right asymmetric ductal epithelial growth in MMTV-cNeu mice by Robichaux, J P, Hallett, R M, Fuseler, J W, Hassell, J A, Ramsdell, A F

“…Significant left–right (L–R) differences in tumor incidence and disease outcome occur for cancers of paired organs, including the breasts; however, the basis…”
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Induction of Endocardial Cushion Tissue in the Avian Heart is Regulated, in Part, by TGFβ-3-Mediated Autocrine Signaling by Ramsdell, Ann F., Markwald, Roger R.

“…Valvuloseptal morphogenesis of the primitive heart tube into a four-chambered organ requires the formation of endocardial cushion tissue. The latter is the…”
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A Laboratory Guide to the Mammalian Embryo . Edited by David K  Gardner, Michelle  Lane , and , Andrew J  Watson. Oxford and New York: Oxford University Press . $99.50 (hardcover); $69.50 (paper). xiv + 394 p + 8 pl; ill.; index. ISBN: 0–19–517151–9 (hc); 0–19–514226–8 (pb). 2004 by Ramsdell, Ann F

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Left‐right lineage analysis of the embryonic Xenopus heart reveals a novel framework linking congenital cardiac defects and laterality disease by Ramsdell, Ann F., Bernanke, Jayne M., Trusk, Thomas C.

“…Heterotaxy syndrome is characterized by abnormal thoracic and/or visceral organ left‐right (LR) asymmetry. The significant morbidity and mortality associated…”
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