Search Results - "Ramsawhook, Ashley"

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    Wilms' Tumor Protein 1 and Enzymatic Oxidation of 5-Methylcytosine in Brain Tumors: Potential Perspectives by Ramsawhook, Ashley, Ruzov, Alexey, Coyle, Beth

    “…The patterns of 5-methylcytosine (5mC) and its oxidized derivatives, 5-hydroxymethylcytosine, 5-formylcytosine, and 5-carboxylcytosine (5caC) are reportedly…”
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    Journal Article
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    Immunostaining for DNA Modifications: Computational Analysis of Confocal Images by Ramsawhook, Ashley H, Lewis, Lara C, Eleftheriou, Maria, Abakir, Abdulkadir, Durczak, Paulina, Markus, Robert, Rajani, Seema, Hannan, Nicholas R F, Coyle, Beth, Ruzov, Alexey

    Published in Journal of visualized experiments (07-09-2017)
    “…For several decades, 5-methylcytosine (5mC) has been thought to be the only DNA modification with a functional significance in metazoans. The discovery of…”
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    Journal Article
  4. 4

    Investigating the Interplay Between Wilms' Tumour Protein 1 and Oxidised Forms of 5-Methylcytosine in Brain Tumours by Ramsawhook, Ashley

    Published 01-01-2020
    “…5-methylcytosine (5mC) is an epigenetic modification usually associated with transcriptional repression. The Ten–Eleven Translocation proteins (Tet1/2/3) can…”
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    Dissertation
  5. 5

    Medulloblastoma and ependymoma cells display increased levels of 5-carboxylcytosine and elevated TET1 expression by Ramsawhook, Ashley, Lewis, Lara, Coyle, Beth, Ruzov, Alexey

    Published in Clinical epigenetics (13-02-2017)
    “…Alteration of DNA methylation (5-methylcytosine, 5mC) patterns represents one of the causes of tumorigenesis and cancer progression. Tet proteins can oxidise…”
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    Journal Article
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