Search Results - "Rampersaud, Sham"
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The Effect of Cage Shape on Nanoparticle-Based Drug Carriers: Anticancer Drug Release and Efficacy via Receptor Blockade Using Dextran-Coated Iron Oxide Nanocages
Published in Nano letters (14-12-2016)“…Although a range of nanoparticles have been developed as drug delivery systems in cancer therapeutics, this approach faces several important challenges…”
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Engineered niches model the onset of metastasis
Published in Nature biomedical engineering (01-12-2018)“…A humanized biomaterial microenvironment that mimics the pre-metastatic niche captures disseminated tumour cells and recapitulates metastatic progression after…”
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CXCR4+ Treg cells control serum IgM levels and natural IgM autoantibody production by B-1 cells in the bone marrow
Published in The Journal of experimental medicine (04-07-2022)“…Regulatory T (Treg) cells represent a specialized lineage of suppressive CD4+ T cells whose functionality is critically dependent on their ability to migrate…”
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Conserved transcriptional connectivity of regulatory T cells in the tumor microenvironment informs new combination cancer therapy strategies
Published in Nature immunology (01-06-2023)“…While regulatory T (T reg ) cells are traditionally viewed as professional suppressors of antigen presenting cells and effector T cells in both autoimmunity…”
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Starfysh integrates spatial transcriptomic and histologic data to reveal heterogeneous tumor-immune hubs
Published in Nature biotechnology (21-03-2024)“…Spatially resolved gene expression profiling provides insight into tissue organization and cell-cell crosstalk; however, sequencing-based spatial…”
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The effect of cage shape on nanoparticle-based drug carriers: Anti-cancer drug release and efficacy via receptor blockade using dextran-coated iron oxide nanocages
Published in Nano letters (01-12-2016)“…Although a range of nanoparticles have been developed as drug delivery systems in cancer therapeutics, this approach faces several important challenges…”
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Functional multiomics reveals genetic and pharmacologic regulation of surface CD38 in multiple myeloma
Published in Blood Neoplasia (01-09-2024)“…•CRISPR interference screening and patient epigenetic analysis reveal regulators of CD38 surface expression including XBP1 and SPI1.•CD38 knockdown does not…”
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