Search Results - "Ramos‐Molina, Bruno"

Epigenetic regulation of white adipose tissue in the onset of obesity and metabolic diseases by Castellano‐Castillo, Daniel, Ramos‐Molina, Bruno, Cardona, Fernando, Queipo‐Ortuño, María Isabel

“…Summary Obesity and metabolic syndrome are among the most prevalent health problems in developed countries. The impairment of adipose tissue (AT) function is…”
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Gut microbiota and related metabolites in the pathogenesis of nonalcoholic steatohepatitis and its resolution after bariatric surgery by Martínez‐Montoro, José Ignacio, Kuchay, Mohammad Shafi, Balaguer‐Román, Andrés, Martínez‐Sánchez, María Antonia, Frutos, María Dolores, Fernández‐García, José Carlos, Ramos‐Molina, Bruno

“…Summary Nonalcoholic fatty liver disease (NAFLD) is increasing in parallel with the rising prevalence of obesity, leading to major health and socioeconomic…”
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Increased hepatic putrescine levels as a new potential factor related to the progression of metabolic dysfunction‐associated steatotic liver disease by Núñez‐Sánchez, María Ángeles, Martínez‐Sánchez, María Antonia, Sierra‐Cruz, Marta, Lambertos, Ana, Rico‐Chazarra, Sara, Oliva‐Bolarín, Alba, Balaguer‐Román, Andrés, Yuste, José Enrique, Martínez, Carlos Manuel, Mika, Adriana, Frutos, María Dolores, Llamoza‐Torres, Camilo J, Córdoba‐Chacón, José, Ramos‐Molina, Bruno

“…Metabolic dysfunction‐associated steatotic liver disease (MASLD) is a chronic liver condition that often progresses to more advanced stages, such as metabolic…”
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Metabotypes of response to bariatric surgery independent of the magnitude of weight loss by Palau-Rodriguez, Magali, Tulipani, Sara, Marco-Ramell, Anna, Miñarro, Antonio, Jáuregui, Olga, Sanchez-Pla, Alex, Ramos-Molina, Bruno, Tinahones, Francisco J, Andres-Lacueva, Cristina

“…Bariatric surgery is considered the most efficient treatment for morbid obesity and its related diseases. However, its role as a metabolic modifier is not well…”
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The Role of Fatty Acids in Non-Alcoholic Fatty Liver Disease Progression: An Update by Hliwa, Aleksandra, Ramos-Molina, Bruno, Laski, Dariusz, Mika, Adriana, Sledzinski, Tomasz

“…Non-alcoholic fatty liver disease (NAFLD) is a major public health problem worldwide. NAFLD (both simple steatosis and steatohepatitis) is characterized by…”
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PCSK1 Mutations and Human Endocrinopathies: From Obesity to Gastrointestinal Disorders by Stijnen, Pieter, Ramos-Molina, Bruno, O'Rahilly, Stephen, Creemers, John W. M

“…Prohormone convertase 1/3, encoded by the PCSK1 gene, is a serine endoprotease that is involved in the processing of a variety of proneuropeptides and…”
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Non-alcoholic fatty liver disease-related fibrosis and sarcopenia: An altered liver-muscle crosstalk leading to increased mortality risk by Kuchay, Mohammad Shafi, Martínez-Montoro, José Ignacio, Kaur, Parjeet, Fernández-García, José Carlos, Ramos-Molina, Bruno

“…In the last few decades, the loss of skeletal muscle mass and function, known as sarcopenia, has significantly increased in prevalence, becoming a major global…”
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Gut Microbiota-Mediated Inflammation and Gut Permeability in Patients with Obesity and Colorectal Cancer by Sánchez-Alcoholado, Lidia, Ordóñez, Rafael, Otero, Ana, Plaza-Andrade, Isaac, Laborda-Illanes, Aurora, Medina, José Antonio, Ramos-Molina, Bruno, Gómez-Millán, Jaime, Queipo-Ortuño, María Isabel

“…Obesity is considered an important factor that increases the risk of colorectal cancer (CRC). So far, the association of gut microbiota with both obesity and…”
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Dietary and Gut Microbiota Polyamines in Obesity- and Age-Related Diseases by Ramos-Molina, Bruno, Queipo-Ortuño, Maria Isabel, Lambertos, Ana, Tinahones, Francisco J, Peñafiel, Rafael

“…The polyamines putrescine, spermidine, and spermine are widely distributed polycationic compounds essential for cellular functions. Intracellular polyamine…”
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Leptin Signaling in Obesity and Colorectal Cancer by Socol, Claudia Terezia, Chira, Alexandra, Martinez-Sanchez, Maria Antonia, Nuñez-Sanchez, Maria Angeles, Maerescu, Cristina Maria, Mierlita, Daniel, Rusu, Alexandru Vasile, Ruiz-Alcaraz, Antonio Jose, Trif, Monica, Ramos-Molina, Bruno

“…Obesity and colorectal cancer (CRC) are among the leading diseases causing deaths in the world, showing a complex multifactorial pathology. Obesity is…”
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Posttranslational processing of FGF23 in osteocytes during the osteoblast to osteocyte transition by Yamamoto, Hiroyuki, Ramos-Molina, Bruno, Lick, Adam N, Prideaux, Matthew, Albornoz, Valeria, Bonewald, Lynda, Lindberg, Iris

“…Abstract FGF23 is an O-glycosylated circulating peptide hormone with a critical role in phosphate homeostasis; it is inactivated by cellular proprotein…”
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Relationships of Gut Microbiota Composition, Short-Chain Fatty Acids and Polyamines with the Pathological Response to Neoadjuvant Radiochemotherapy in Colorectal Cancer Patients by Sánchez-Alcoholado, Lidia, Laborda-Illanes, Aurora, Otero, Ana, Ordóñez, Rafael, González-González, Alicia, Plaza-Andrades, Isaac, Ramos-Molina, Bruno, Gómez-Millán, Jaime, Queipo-Ortuño, María Isabel

“…Emerging evidence has suggested that dysbiosis of the gut microbiota may influence the drug efficacy of colorectal cancer (CRC) patients during cancer…”
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Hepatic and serum branched‐chain fatty acid profile in patients with nonalcoholic fatty liver disease: A case–control study by Martínez‐Montoro, José Ignacio, Núñez‐Sánchez, María Ángeles, Martinez‐Sanchez, María Antonia, Balaguer‐Román, Andrés, Fernández‐Ruiz, Virginia E., Ferrer‐Gómez, Mercedes, Sledzinski, Tomasz, Frutos, María Dolores, Fernández‐García, José Carlos, Mika, Adriana, Ramos‐Molina, Bruno

“…Objective Alterations in the hepatic lipidome are a crucial factor involved in the pathophysiology of nonalcoholic fatty liver disease (NAFLD). The aim of this…”
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Analysis of the anti-inflammatory potential of Brassica bioactive compounds in a human macrophage-like cell model derived from HL-60 cells by Ruiz-Alcaraz, Antonio José, Martínez-Sánchez, María Antonia, García-Peñarrubia, Pilar, Martinez-Esparza, María, Ramos-Molina, Bruno, Moreno, Diego A.

“…Chronic inflammatory diseases are major causes of global morbidity and mortality. Acute inflammation is meant to protect the body against foreign agents, but…”
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Non-Alcoholic Fatty Liver Disease in Lean and Non-Obese Individuals: Current and Future Challenges by Kuchay, Mohammad Shafi, Martínez-Montoro, José Ignacio, Choudhary, Narendra Singh, Fernández-García, José Carlos, Ramos-Molina, Bruno

“…Non-alcoholic fatty liver disease (NAFLD), which approximately affects a quarter of the world’s population, has become a major public health concern. Although…”
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Differential Effects of Furin Deficiency on Insulin Receptor Processing and Glucose Control in Liver and Pancreatic β Cells of Mice by Coppola, Ilaria, Brouwers, Bas, Meulemans, Sandra, Ramos-Molina, Bruno, Creemers, John W M

“…The insulin receptor (IR) is critically involved in maintaining glucose homeostasis. It undergoes proteolytic cleavage by proprotein convertases, which is an…”
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RNA expression changes driven by altered epigenetics status related to NASH etiology by Castellano-Castillo, Daniel, Ramos-Molina, Bruno, Frutos, María Dolores, Arranz-Salas, Isabel, Reyes-Engel, Armando, Queipo-Ortuño, María Isabel, Cardona, Fernando

“…Non-alcoholic fatty liver disease (NAFLD) is a growing health problem due to the increased obesity rates, among other factors. In its more severe stage (NASH),…”
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New insights of polyamine metabolism in testicular physiology: A role of ornithine decarboxylase antizyme inhibitor 2 (AZIN2) in the modulation of testosterone levels and sperm motility by Lambertos, Ana, Ramos-Molina, Bruno, López-Contreras, Andrés J, Cremades, Asunción, Peñafiel, Rafael

“…The specific role of polyamines in the testis physiology is not fully understood. Antizymes (OAZs) and antizyme inhibitors (AZINs) are modulators of ornithine…”
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Changes in the Serum Fatty Acid Profile After Anhepatic Phase of Orthotopic Liver Transplantation Procedure by Hliwa, Aleksandra, Mika, Adriana, Sledzinski, Maciej, Laski, Dariusz, Ramos-Molina, Bruno, Sledzinski, Tomasz

“…During orthotopic liver transplantation (OLT), the patients' body remains deprived of this organ for some time, which could cause critical changes in the…”
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Gut Microbiota Composition Is Associated With the Global DNA Methylation Pattern in Obesity by Ramos-Molina, Bruno, Sánchez-Alcoholado, Lidia, Cabrera-Mulero, Amanda, Lopez-Dominguez, Raul, Carmona-Saez, Pedro, Garcia-Fuentes, Eduardo, Moreno-Indias, Isabel, Tinahones, Francisco J

“…Obesity and obesity-related metabolic diseases are characterized by gut microbiota and epigenetic alterations. Recent insight has suggested the existence of a…”
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