Search Results - "Ramos, Rúben J.J"

Farnesoid X Receptor Activation Promotes Hepatic Amino Acid Catabolism and Ammonium Clearance in Mice by Massafra, Vittoria, Milona, Alexandra, Vos, Harmjan R, Ramos, Rúben J.J, Gerrits, Johan, Willemsen, Ellen C.L, Ramos Pittol, José M, Ijssennagger, Noortje, Houweling, Martin, Prinsen, Hubertus C.M.T, Verhoeven-Duif, Nanda M, Burgering, Boudewijn M, van Mil, Saskia W.C

“…Background & Aims The nuclear receptor subfamily 1 group H member 4 (NR1H4 or farnesoid X receptor [FXR]) regulates bile acid synthesis, transport, and…”
Get full text

Improved cognition, mild anxiety-like behavior and decreased motor performance in pyridoxal phosphatase-deficient mice by Jeanclos, Elisabeth, Albersen, Monique, Ramos, Rúben J.J., Raab, Annette, Wilhelm, Christian, Hommers, Leif, Lesch, Klaus-Peter, Verhoeven-Duif, Nanda M., Gohla, Antje

“…Pyridoxal 5′-phosphate (PLP) is an essential cofactor in the catalysis of ~140 different enzymatic reactions. A pharmacological elevation of cellular PLP…”
Get full text

GLS hyperactivity causes glutamate excess, infantile cataract and profound developmental delay by Rumping, Lynne, Tessadori, Federico, Pouwels, Petra J W, Vringer, Esmee, Wijnen, Jannie P, Bhogal, Alex A, Savelberg, Sanne M C, Duran, Karen J, Bakkers, Mark J G, Ramos, Rúben J J, Schellekens, Peter A W, Kroes, Hester Y, Klomp, Dennis W J, Black, Graeme C M, Taylor, Rachel L, Bakkers, Jeroen P W, Prinsen, Hubertus C M T, van der Knaap, Marjo S, Dansen, Tobias B, Rehmann, Holger, Zwartkruis, Fried J T, Houwen, Roderick H J, van Haaften, Gijs, Verhoeven-Duif, Nanda M, Jans, Judith J M, van Hasselt, Peter M

“…Abstract Loss-of-function mutations in glutaminase (GLS), the enzyme converting glutamine into glutamate, and the counteracting enzyme glutamine synthetase…”
Get full text