Search Results - "Ramos, Maritza"
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A Novel Combination of Sotorasib and Metformin Enhances Cytotoxicity and Apoptosis in KRAS-Mutated Non-Small Cell Lung Cancer Cell Lines through MAPK and P70S6K Inhibition
Published in International journal of molecular sciences (22-02-2023)“…Novel inhibitors of KRAS with G12C mutation (sotorasib) have demonstrated short-lasting responses due to resistance mediated by the AKT-mTOR-P70S6K pathway. In…”
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STK11 and KEAP1 mutations in non-small cell lung cancer patients: Descriptive analysis and prognostic value among Hispanics (STRIKE registry-CLICaP)
Published in Lung cancer (Amsterdam, Netherlands) (01-08-2022)“…•STK11 and KEAP1 have been described as poor prognostic factors in patients treated with immune checkpoint inhibitors (ICIs).•This is the larger study to…”
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3
Risk of Developing Checkpoint Immune Pneumonitis and Its Effect on Overall Survival in Non-small Cell Lung Cancer Patients Previously Treated With Radiotherapy
Published in Frontiers in oncology (29-09-2020)“…Immune checkpoint inhibitor-related pneumonitis (ICIP) is a potentially life threatening immune-related adverse event (irAE), especially in non-small cell lung…”
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4
Cost-effectiveness analysis of first and second-generation EGFR tyrosine kinase inhibitors as first line of treatment for patients with NSCLC harboring EGFR mutations
Published in BMC cancer (01-09-2020)“…Tyrosine-kinase inhibitors (TKIs) have become the cornerstone treatment of patients with non-small cell lung cancer that harbor oncogenic EGFR mutations. The…”
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5
Clinical Impact of the COVID‐19 Pandemic in Mexican Patients with Thoracic Malignancies
Published in The oncologist (Dayton, Ohio) (01-12-2021)“…Background Accumulated evidence indicates that patients with lung cancer are a vulnerable population throughout the pandemic. Limited information is available…”
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LKB1 Loss Assessed by Immunohistochemistry as a Prognostic Marker to First-Line Therapy in Advanced Non-Small-Cell Lung Cancer
Published in Current oncology (Toronto) (26-12-2022)“…(1) Background: Liver kinase B1 (LKB1) is a tumor suppressor gene involved in cell growth and metabolism. However, its alterations are not routinely assessed…”
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Efficacy, Safety, and Cost-Minimization Analysis of Continuous Infusion of Low-Dose Gemcitabine Plus Cisplatin in Patients With Unresectable Malignant Pleural Mesothelioma
Published in Frontiers in oncology (20-04-2021)“…Malignant pleural mesothelioma (MPM) is rare and aggressive neoplasia, with a poor prognosis; furthermore, the monetary cost of its treatment represents a…”
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Re‐irradiation in patients with progressive or recurrent brain metastases from extracranial solid tumors: A novel prognostic index
Published in Cancer medicine (Malden, MA) (01-01-2023)“…Background Most studies evaluating factors associated with the survival of patients with brain metastases (BM) have focused on patients with newly diagnosed…”
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Evaluation of a risk-sharing agreement for atezolizumab treatment in patients with non-small cell lung cancer: a strategy to improve access in low-income countries
Published in The oncologist (Dayton, Ohio) (19-10-2024)“…Using immune checkpoint inhibitors (IO) is a promising approach to maximize clinical benefits for patients with non-small cell lung cancer (NSCLC). PD-L1…”
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Early Incorporation to Palliative Care (EPC) in Patients With Advanced Non-Small Cell Lung Cancer: The PACO Randomized Clinical Trial
Published in The oncologist (Dayton, Ohio) (03-10-2024)“…Patients with non-small cell lung cancer (NSCLC) experience a considerable disease burden, evident in symptomatic and psychological spheres. Advanced cancer…”
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A high number of co-occurring genomic alterations detected by NGS is associated with worse clinical outcomes in advanced EGFR-mutant lung adenocarcinoma: Data from LATAM population
Published in Lung cancer (Amsterdam, Netherlands) (01-12-2022)“…•Co-occurring genomic alterations at diagnosis might represent de novo and primary resistance mechanisms to tyrosine kinase inhibitors (TKIs) in advanced…”
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12
Impact of KRASG12D subtype and concurrent pathogenic mutations on advanced non-small cell lung cancer outcomes
Published in Clinical & translational oncology (01-04-2024)“…Purpose Mutations in the Kirsten rat sarcoma viral (KRAS) oncogene constitute a significant driver of lung adenocarcinoma, present in 10–40% of patients, which…”
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The Evolution of Clinically Aggressive Triple-Negative Breast Cancer Shows a Large Mutational Diversity and Early Metastasis to Lymph Nodes
Published in Cancers (12-10-2021)“…In triple-negative breast cancer (TNBC), only 30% of patients treated with neoadjuvant chemotherapy achieve a pathological complete response after treatment…”
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Comprehensive Genomic Profile of Heterogeneous Long Follow-Up Triple-Negative Breast Cancer and Its Clinical Characteristics Shows DNA Repair Deficiency Has Better Prognostic
Published in Genes (19-11-2020)“…Triple-negative breast cancer (TNBC) presents a marked diversity at the molecular level, which promotes a clinical heterogeneity that further complicates…”
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Impacto de la eficiencia en la gestión de la política educativa en salud integral de Lima Metropolitana
Published in Revista de climatología (21-11-2023)“…Las políticas públicas en educación básica regular (PP EBR) se investigaron desde diferentes contextos que se evidenciaron durante el proceso de revisión desde…”
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A phase II study of alectinib in combination with bevacizumab as first-line treatment in advanced NSCLC with confirmed ALK fusion: ALEK-B trial
Published in Journal of clinical oncology (01-06-2022)“…9074 Background: Alectinib is one of the standard treatment options as an upfront therapy in advanced ALK-rearranged non-small-cell lung cancer. However, all…”
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Porno, pornógrafos, monstruos. Una aproximación pospornográfica al cuerpo bogotano
Published in Maguaré (Bogota, Colombia) (01-07-2015)“…El objetivo de este artículo es establecer, de la mano de Michel Foucault, Paul B. Preciado y Hilderman Cardona, entre otros autores, un mapa que exhiba…”
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Nitroglycerin (NTG) plus whole intracranial radiotherapy for brain metastases (BM) in non-small cell cancer patient (NSCLC): A randomized open label, phase II clinical trial
Published in Journal of clinical oncology (20-05-2021)“…Abstract only 9114 Background: Hypoxia has been associated with chemo-radioresistance secondary to Vascular Endothelial Growth Factor Receptor induced by…”
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Recommendations for detection, prioritization, and treatment of thoracic oncology patients during the COVID‐19 pandemic: the THOCOoP cooperative group
Published in Critical reviews in oncology/hematology (01-09-2020)“…The world currently faces a pandemic due to SARS-CoV-2. Relevant information has emerged regarding the higher risk of poor outcomes in lung cancer patients. As…”
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Telework Decision Strategy: A Systematic Review
Published 01-01-2020“…The U.S. Government telework program has stagnated, with only 40 percent of the population considered telework eligible, a slight decline from 2012, and less…”
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Dissertation