Search Results - "Ramos, Jorge G"
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Perinatal exposure to bisphenol A (BPA) impairs neuroendocrine mechanisms regulating food intake and kisspetin system in adult male rats. Evidences of metabolic disruptor hypothesis
Published in Molecular and cellular endocrinology (01-01-2020)“…Bisphenol A (BPA) is a compound used in the polymerization of plastic polycarbonates. It is an endocrine disruptor and it has been postulated to be an…”
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Neonatal Exposure to Bisphenol A Alters Rat Uterine Implantation-Associated Gene Expression and Reduces the Number of Implantation Sites
Published in Endocrinology (Philadelphia) (01-03-2011)“…Neonatal exposure to bisphenol-A decreases the number of implantation sites in association with alterations in the endocrine-regulated Hoxa10 gene pathways…”
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Neonatal exposure to bisphenol A modifies the abundance of estrogen receptor α transcripts with alternative 5′-untranslated regions in the female rat preoptic area
Published in Journal of endocrinology (01-07-2007)“…The xenoestrogen bisphenol A (BPA) is commonly ingested by humans. We examined the effects of neonatal exposure to low versus high doses of BPA over the…”
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Developmental Exposure to Bisphenol A Impairs the Uterine Response to Ovarian Steroids in the Adult
Published in Endocrinology (Philadelphia) (01-11-2008)“…Morphoregulator genes like members of the Hox gene family regulate uterine development and are associated with endocrine-related processes such as endometrial…”
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Effects of Neonatal Exposure to Bisphenol A on Steroid Regulation of Vascular Endothelial Growth Factor Expression and Endothelial Cell Proliferation in the Adult Rat Uterus
Published in Biology of reproduction (01-01-2010)“…Hormonally controlled vascular changes play a key role in endometrial development and in the differentiation process necessary for implantation. Vascular…”
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Bisphenol A Induces Both Transient and Permanent Histofunctional Alterations of the Hypothalamic-Pituitary-Gonadal Axis in Prenatally Exposed Male Rats
Published in Endocrinology (Philadelphia) (01-07-2003)“…Exposure to bisphenol A (BPA) in utero has been shown to induce alterations in the prostate of 30-d-old Wistar rats. Herein, we examine both the time course of…”
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Agrochemicals and neurogenesis
Published in Molecular and cellular endocrinology (15-06-2020)“…Agrochemicals or pesticides are compounds widely used to prevent, destroy or mitigate pests such as insects, rodents, herbs and weeds. However, most of them…”
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Evidence Supporting a Role for Constitutive Ghrelin Receptor Signaling in Fasting-Induced Hyperphagia in Male Mice
Published in Endocrinology (Philadelphia) (01-02-2018)“…Ghrelin is a potent orexigenic peptide hormone that acts through the growth hormone secretagogue receptor (GHSR), a G protein-coupled receptor highly expressed…”
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Uterine ERα epigenetic modifications are induced by the endocrine disruptor endosulfan in female rats with impaired fertility
Published in Molecular and cellular endocrinology (15-10-2017)“…High ERα activity may disrupt the window of uterine receptivity, causing defective implantation. We investigated whether implantation failures prompted by…”
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Plasma cell-free DNA as a monitoring tool for high-risk pregnancies associated with antiphospholipid syndrome
Published in Thrombosis research (01-09-2024)“…Despite thromboprophylaxis, women with antiphospholipid syndrome (APS) face high-risk pregnancies due to proinflammatory and prothrombotic states. This…”
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Cellular Turnover in the Rat Uterine Cervix and Its Relationship to Estrogen and Progesterone Receptor Dynamics
Published in Biology of reproduction (01-09-2002)“…Histoarchitectural changes of the uterine cervix allow its successful adaptation to different physiological conditions. In this study, we evaluated cell…”
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A Reliable Method for Quantifying Plasma Cell-Free DNA Using an Internal Standard Strategy: Evaluation in a Cohort of Non-Pregnant and Pregnant Women
Published in Reproductive sciences (Thousand Oaks, Calif.) (01-04-2024)“…The use of plasma cell-free DNA (cfDNA) as a useful biomarker in obstetric clinical practice has been delayed due to the lack of reliable quantification…”
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Diethylstilbestrol alters the population dynamic of neural precursor cells in the neonatal male rat dentate gyrus
Published in Brain research bulletin (30-03-2007)“…Abstract Little is known about how estrogens influence neurogenesis in the newborn male rodent. Herein, we examined the effects of neonatal diethylstilbestrol…”
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Perinatal exposure to bisphenol A modifies the transcriptional regulation of the β-Casein gene during secretory activation of the rat mammary gland
Published in Molecular and cellular endocrinology (05-01-2017)“…With the aim to analyze whether bisphenol A (BPA) modifies β-Casein (β-Cas) synthesis and transcriptional regulation in perinatally exposed animals, here,…”
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Environmental enrichment attenuates the age-related decline in the mRNA expression of steroidogenic enzymes and reduces the methylation state of the steroid 5α-reductase type 1 gene in the rat hippocampus
Published in Molecular and cellular endocrinology (05-09-2015)“…•The mRNA expression of hippocampal steroidogenic enzymes decreases during aging.•The promoter methylation of P450scc, 5α-reductase-1 and 3α-HSD increases in…”
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Epigenetic regulation of steroidogenic enzymes expressed in peripheral blood mononuclear cells from healthy individuals and from patients with chronic lymphocytic leukemia
Published in The Journal of steroid biochemistry and molecular biology (01-11-2020)“…•PBMCs from healthy individuals express steroidogenic enzymes.•PBMCs of CLL patients have lower expression of 5α-R 1, 5α-R 3, 3α-HSD 3, 17β-HSD 1 and 17β-HSD…”
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Developmental exposure to bisphenol A alters the differentiation and functional response of the adult rat uterus to estrogen treatment
Published in Reproductive toxicology (Elmsford, N.Y.) (01-04-2015)“…•Perinatal exposure to BPA increased the incidence of uterine abnormalities in rats.•The occurrence of glandular alterations increased in BPA-exposed rats…”
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Disruption of the developmental programming of the gonad of the broad snouted caiman (Caiman latirostris) after in ovo exposure to atrazine
Published in Environmental science and pollution research international (01-03-2023)“…Environmental exposure to agrochemicals during early stages of development can induce subtle alterations that could permanently affect normal physiology…”
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Neonatal exposure to low doses of endosulfan induces implantation failure and disrupts uterine functional differentiation at the pre-implantation period in rats
Published in Molecular and cellular endocrinology (05-02-2015)“…•Neonatal exposure to endosulfan induces implantation failure, causing subfertility.•Aberrant endometrial proliferation and Hoxa10 expression might affect…”
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Sex- and age-associated differences in episodic-like memory and transcriptional regulation of hippocampal steroidogenic enzymes in rats
Published in Molecular and cellular endocrinology (15-07-2018)“…The aim of this study was to evaluate the episodic-like memory (ELM) and the transcriptional regulation of the enzymes involved in hippocampal allopregnanolone…”
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