Search Results - "Ramos, F. M"

Genes involved in the osteoarthritis process identified through genome wide expression analysis in articular cartilage; the RAAK study by Ramos, Yolande F M, den Hollander, Wouter, Bovée, Judith V M G, Bomer, Nils, van der Breggen, Ruud, Lakenberg, Nico, Keurentjes, J Christiaan, Goeman, Jelle J, Slagboom, P Eline, Nelissen, Rob G H H, Bos, Steffan D, Meulenbelt, Ingrid

“…Identify gene expression profiles associated with OA processes in articular cartilage and determine pathways changing during the disease process. Genome wide…”
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Novel Genetic Variants for Cartilage Thickness and Hip Osteoarthritis by Castaño-Betancourt, Martha C, Evans, Dan S, Ramos, Yolande F M, Boer, Cindy G, Metrustry, Sarah, Liu, Youfang, den Hollander, Wouter, van Rooij, Jeroen, Kraus, Virginia B, Yau, Michelle S, Mitchell, Braxton D, Muir, Kenneth, Hofman, Albert, Doherty, Michael, Doherty, Sally, Zhang, Weiya, Kraaij, Robert, Rivadeneira, Fernando, Barrett-Connor, Elizabeth, Maciewicz, Rose A, Arden, Nigel, Nelissen, Rob G H H, Kloppenburg, Margreet, Jordan, Joanne M, Nevitt, Michael C, Slagboom, Eline P, Hart, Deborah J, Lafeber, Floris, Styrkarsdottir, Unnur, Zeggini, Eleftheria, Evangelou, Evangelos, Spector, Tim D, Uitterlinden, Andre G, Lane, Nancy E, Meulenbelt, Ingrid, Valdes, Ana M, van Meurs, Joyce B J

“…Osteoarthritis is one of the most frequent and disabling diseases of the elderly. Only few genetic variants have been identified for osteoarthritis, which is…”
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Thyroid hormone induces ossification and terminal maturation in a preserved OA cartilage biomimetic model by Korthagen, N M, Houtman, E, Boone, I, Coutinho de Almeida, R, Sivasubramaniyan, K, Mahdad, R, Nelissen, R G H H, Ramos, Y F M, Tessari, M A, Meulenbelt, I

“…To characterize aspects of triiodothyronine (T3) induced chondrocyte terminal maturation within the molecular osteoarthritis pathophysiology using the…”
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Elucidating mechano-pathology of osteoarthritis: transcriptome-wide differences in mechanically stressed aged human cartilage explants by Houtman, Evelyn, Tuerlings, Margo, Riechelman, Janne, Suchiman, Eka H. E. D, van der Wal, Robert J. P, Nelissen, Rob G. H. H, Mei, Hailiang, Ramos, Yolande F. M, Coutinho de Almeida, Rodrigo, Meulenbelt, Ingrid

“…Abstract Background Failing of intrinsic chondrocyte repair after mechanical stress is known as one of the most important initiators of osteoarthritis…”
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Characterizing the secretome of licensed hiPSC-derived MSCs by Ramos, Yolande F M, Tertel, Tobias, Shaw, Georgina, Staubach, Simon, de Almeida, Rodrigo Coutinho, Suchiman, Eka, Kuipers, Thomas B, Mei, Hailiang, Barry, Frank, Murphy, Mary, Giebel, Bernd, Meulenbelt, Ingrid

“…Although mesenchymal stromal cells (MSCs) from primary tissues have been successfully applied in the clinic, their expansion capabilities are limited and…”
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Transcriptional Associations of Osteoarthritis‐Mediated Loss of Epigenetic Control in Articular Cartilage by den Hollander, Wouter, Ramos, Yolande F. M., Bomer, Nils, Elzinga, Stefan, van der Breggen, Ruud, Lakenberg, Nico, de Dijcker, Wesley J., Suchiman, H. Eka D., Duijnisveld, Bouke J., Houwing‐Duistermaat, Jeanine J., Slagboom, P. Eline, Bos, Steffan D., Nelissen, Rob G. H. H., Meulenbelt, Ingrid

“…Objective To identify osteoarthritis (OA) progression–modulating pathways in articular cartilage and their respective regulatory epigenetic and genetic…”
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The effect of forced exercise on knee joints in Dio2(-/-) mice: type II iodothyronine deiodinase-deficient mice are less prone to develop OA-like cartilage damage upon excessive mechanical stress by Bomer, Nils, Cornelis, Frederique M F, Ramos, Yolande F M, den Hollander, Wouter, Storms, Lies, van der Breggen, Ruud, Lakenberg, Nico, Slagboom, P Eline, Meulenbelt, Ingrid, Lories, Rik J L

“…To further explore deiodinase iodothyronine type 2 (DIO2) as a therapeutic target in osteoarthritis (OA) by studying the effects of forced mechanical loading…”
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The growth performance and parasite load of angelfish juveniles Pterophyllum scalare kept at different stocking densities in two rearing systems by Santos, R F B, Zanella, J, Ferreira, A C V, Couto, M V, Dias, H M, Abe, H A, Ramos, F M, Paixão, P E G, Martins, M L, Fujimoto, R Y, Honorato, C A

“…This study evaluated the growth performance and parasite load of angelfish juveniles Pterophyllum scalare kept at different stocking densities using two…”
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Hyper-physiologic mechanical cues, as an osteoarthritis disease-relevant environmental perturbation, cause a critical shift in set points of methylation at transcriptionally active CpG sites in neo-cartilage organoids by Bloks, Niek G C, Dicks, Amanda, Harissa, Zainab, Nelissen, Rob G H H, Hajmousa, Ghazaleh, Ramos, Yolande F M, de Almeida, Rodrigo Coutinho, Guilak, Farshid, Meulenbelt, Ingrid

“…Osteoarthritis (OA) is a complex, age-related multifactorial degenerative disease of diarthrodial joints marked by impaired mobility, joint stiffness, pain,…”
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Knee and hip articular cartilage have distinct epigenomic landscapes: implications for future cartilage regeneration approaches by den Hollander, W, Ramos, Y F M, Bos, S D, Bomer, N, van der Breggen, R, Lakenberg, N, de Dijcker, W J, Duijnisveld, Bouke J, Slagboom, P E, Nelissen, Rob G H H, Meulenbelt, I

“…To elucidate the functional epigenomic landscape of articular cartilage in osteoarthritis (OA) affected knee and hip joints in relation to gene expression…”
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Ornamental fish of economic and biological importance to the Xingu River by Ramos, F M, Araújo, M L G, Prang, G, Fujimoto, R Y

“…In the city of Altamira, over 200 species of fish are traded as ornamentals. The increase of the market value leads to increased selective fishing and…”
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Identification and characterization of two consistent osteoarthritis subtypes by transcriptome and clinical data integration by Coutinho de Almeida, Rodrigo, Mahfouz, Ahmed, Mei, Hailiang, Houtman, Evelyn, den Hollander, Wouter, Soul, Jamie, Suchiman, Eka, Lakenberg, Nico, Meessen, Jennifer, Huetink, Kasper, Nelissen, Rob G H H, Ramos, Yolande F M, Reinders, Marcel, Meulenbelt, Ingrid

“…Abstract Objective To identify OA subtypes based on cartilage transcriptomic data in cartilage tissue and characterize their underlying pathophysiological…”
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Phase transformation studies on YSZ doped with alumina. Part 1: Metastable phases by Nazarpour, S., López-Gándara, C., Ramos, F.M., Cirera, A.

“…The goal of this study is to clarify the effect of the addition of Al 2O 3 on the grain boundaries of yttria stabilized zirconia using high resolution…”
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Aberrant Calreticulin Expression in Articular Cartilage of Dio2 Deficient Mice by Bomer, Nils, Cornelis, Frederique M F, Ramos, Yolande F M, den Hollander, Wouter, Lakenberg, Nico, van der Breggen, Ruud, Storms, Lies, Slagboom, P Eline, Lories, Rik J U, Meulenbelt, Ingrid

“…To identify intrinsic differences in cartilage gene expression profiles between wild-type- and Dio2-/--mice, as a mechanism to investigate factors that…”
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Integrative epigenomics, transcriptomics and proteomics of patient chondrocytes reveal genes and pathways involved in osteoarthritis by Steinberg, Julia, Ritchie, Graham R. S., Roumeliotis, Theodoros I., Jayasuriya, Raveen L., Clark, Matthew J., Brooks, Roger A., Binch, Abbie L. A., Shah, Karan M., Coyle, Rachael, Pardo, Mercedes, Le Maitre, Christine L., Ramos, Yolande F. M., Nelissen, Rob G. H. H., Meulenbelt, Ingrid, McCaskie, Andrew W., Choudhary, Jyoti S., Wilkinson, J. Mark, Zeggini, Eleftheria

“…Osteoarthritis (OA) is a common disease characterized by cartilage degeneration and joint remodeling. The underlying molecular changes underpinning disease…”
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Comorbidity in patients with type 2 diabetes mellitus and heart failure with preserved ejection fraction. Cluster analysis of the RICA registry. Opportunities for improvement by Arévalo Lorido, J C, Carretero Gómez, J, Gómez Huelgas, R, Quirós López, R, Dávila Ramos, M F, Serrado Iglesias, A, Ruiz Laiglesia, F, González Franco, A, Cepeda Rodrigo, J M, Montero-Pérez-Barquero, M

“…AIMThe heterogeneity of patients with heart failure and preserved ejection fraction (HFpEF) is high, thusthis entity tends to be grouped into phenotypes to act…”
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The role of DNA methylation in chondrogenesis of human iPSCs as a stable marker of cartilage quality by Hajmousa, Ghazaleh, de Almeida, Rodrigo Coutinho, Bloks, Niek, Ruiz, Alejandro Rodríguez, Bouma, Marga, Slieker, Roderick, Kuipers, Thomas B, Nelissen, Rob G H H, Ito, Keita, Freund, Christian, Ramos, Yolande F M, Meulenbelt, Ingrid

“…Lack of insight into factors that determine purity and quality of human iPSC (hiPSC)-derived neo-cartilage precludes applications of this powerful technology…”
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RNA Sequencing Reveals Interacting Key Determinants of Osteoarthritis Acting in Subchondral Bone and Articular Cartilage: Identification of IL11 and CHADL as Attractive Treatment Targets by Tuerlings, Margo, Hoolwerff, Marcella, Houtman, Evelyn, Suchiman, Eka H. E. D., Lakenberg, Nico, Mei, Hailiang, Linden, Enrike H. M. J., Nelissen, Rob R. G. H. H., Ramos, Yolande Y. F. M., Coutinho de Almeida, Rodrigo, Meulenbelt, Ingrid

“…Objective To identify key determinants of the interactive pathophysiologic processes in subchondral bone and cartilage in osteoarthritis (OA). Methods We…”
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Cartilage from human-induced pluripotent stem cells: comparison with neo-cartilage from chondrocytes and bone marrow mesenchymal stromal cells by Rodríguez Ruiz, Alejandro, Dicks, Amanda, Tuerlings, Margo, Schepers, Koen, van Pel, Melissa, Nelissen, Rob G. H. H., Freund, Christian, Mummery, Christine L., Orlova, Valeria, Guilak, Farshid, Meulenbelt, Ingrid, Ramos, Yolande F. M.

“…Cartilage has little intrinsic capacity for repair, so transplantation of exogenous cartilage cells is considered a realistic option for cartilage…”
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Parthenocarpy, attractiveness and seed predation by birds in Bursera morelensis by Ramos-Ordoñez, M.F., Arizmendi, M.C.

“…Parthenocarpy (production of seedless fruits) is a characteristic associated with a strategy to reduce seed predation by birds and to increase the…”
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