Search Results - "Ramon, I"

Unraveling the Complex Interplay Between T Cell Metabolism and Function by Klein Geltink, Ramon I, Kyle, Ryan L, Pearce, Erika L

“…Metabolism drives function, on both an organismal and a cellular level. In T cell biology, metabolic remodeling is intrinsically linked to cellular…”
Get full text

Mitochondrial Dynamics Controls T Cell Fate through Metabolic Programming by Buck, Michael D., O’Sullivan, David, Klein Geltink, Ramon I., Curtis, Jonathan D., Chang, Chih-Hao, Sanin, David E., Qiu, Jing, Kretz, Oliver, Braas, Daniel, van der Windt, Gerritje J.W., Chen, Qiongyu, Huang, Stanley Ching-Cheng, O’Neill, Christina M., Edelson, Brian T., Pearce, Edward J., Sesaki, Hiromi, Huber, Tobias B., Rambold, Angelika S., Pearce, Erika L.

“…Activated effector T (TE) cells augment anabolic pathways of metabolism, such as aerobic glycolysis, while memory T (TM) cells engage catabolic pathways, like…”
Get full text

Transsulfuration, minor player or crucial for cysteine homeostasis in cancer by Zhang, Hai-Feng, Klein Geltink, Ramon I., Parker, Seth J., Sorensen, Poul H.

“…Cysteine, a thiol-containing amino acid, is crucial for the synthesis of sulfur-containing biomolecules that control multiple essential cellular activities…”
Get full text

Triacylglycerol synthesis enhances macrophage inflammatory function by Castoldi, Angela, Monteiro, Lauar B., van Teijlingen Bakker, Nikki, Sanin, David E., Rana, Nisha, Corrado, Mauro, Cameron, Alanna M., Hässler, Fabian, Matsushita, Mai, Caputa, George, Klein Geltink, Ramon I., Büscher, Jörg, Edwards-Hicks, Joy, Pearce, Erika L., Pearce, Edward J.

“…Foamy macrophages, which have prominent lipid droplets (LDs), are found in a variety of disease states. Toll-like receptor agonists drive triacylglycerol…”
Get full text

Autonomous Output Feedback Stabilization With Prescribed Settling-Time Bound by Orlov, Yury, Kairuz, Ramon I. Verdes

“…Novel output feedback stabilization is developed for a chain of integrators to impose on the closed-loop system an a priori given settling-time bound…”
Get full text

Acetate Promotes T Cell Effector Function during Glucose Restriction by Qiu, Jing, Villa, Matteo, Sanin, David E., Buck, Michael D., O’Sullivan, David, Ching, Reagan, Matsushita, Mai, Grzes, Katarzyna M., Winkler, Frances, Chang, Chih-Hao, Curtis, Jonathan D., Kyle, Ryan L., Van Teijlingen Bakker, Nikki, Corrado, Mauro, Haessler, Fabian, Alfei, Francesca, Edwards-Hicks, Joy, Maggi, Leonard B., Zehn, Dietmar, Egawa, Takeshi, Bengsch, Bertram, Klein Geltink, Ramon I., Jenuwein, Thomas, Pearce, Edward J., Pearce, Erika L.

“…Competition for nutrients like glucose can metabolically restrict T cells and contribute to their hyporesponsiveness during cancer. Metabolic adaptation to the…”
Get full text

Mitochondrial Priming by CD28 by Klein Geltink, Ramon I, O'Sullivan, David, Corrado, Mauro, Bremser, Anna, Buck, Michael D, Buescher, Joerg M, Firat, Elke, Zhu, Xuekai, Niedermann, Gabriele, Caputa, George, Kelly, Beth, Warthorst, Ursula, Rensing-Ehl, Anne, Kyle, Ryan L, Vandersarren, Lana, Curtis, Jonathan D, Patterson, Annette E, Lawless, Simon, Grzes, Katarzyna, Qiu, Jing, Sanin, David E, Kretz, Oliver, Huber, Tobias B, Janssens, Sophie, Lambrecht, Bart N, Rambold, Angelika S, Pearce, Edward J, Pearce, Erika L

“…T cell receptor (TCR) signaling without CD28 can elicit primary effector T cells, but memory T cells generated during this process are anergic, failing to…”
Get full text

A review of measurement and analysis of electric power quality on shipboard power system networks by Barros, Julio, Diego, Ramón I.

“…Electric power quality is an important aspect of increasing concern in power system networks in ships. A poor power quality not only affects the performance of…”
Get full text

Fever supports CD8⁺ effector T cell responses by promoting mitochondrial translation by O’Sullivan, David, Stanczak, Michal A., Villa, Matteo, Uhl, Franziska M., Corrado, Mauro, Geltink, Ramon I. Klein, Sanin, David E., Apostolova, Petya, Rana, Nisha, Edwards-Hicks, Joy, Grzes, Katarzyna M., Kabat, Agnieszka M., Kyle, Ryan L., Fabri, Mario, Curtis, Jonathan D., Buck, Michael D., Patterson, Annette E., Regina, Annamaria, Field, Cameron S., Baixauli, Francesc, Puleston, Daniel J., Pearce, Edward J., Zeiser, Robert, Pearce, Erika L.

“…Fever can provide a survival advantage during infection. Metabolic processes are sensitive to environmental conditions, but the effect of fever on T cell…”
Get full text

Designing continuous flow reaction of xylan hydrolysis for xylooligosaccharides production in packed-bed reactors using xylanase immobilized on methacrylic polymer-based supports by Romero-Fernández, Maria, Moreno-Perez, Sonia, H. Orrego, Alejandro, Martins de Oliveira, Sandro, I. Santamaría, Ramón, Díaz, Margarita, Guisan, Jose M., Rocha-Martin, Javier

“…[Display omitted] •Xys1Δ immobilized on activated Relizyme R403/S-glyoxyl was selected to set up a PRB for the continuous production of XOS.•The highest…”
Get full text

Interactions of Different Streptomyces Species and Myxococcus xanthus Affect Myxococcus Development and Induce the Production of DK-Xanthenes by Santamaría, Ramón I., Martínez-Carrasco, Ana, Tormo, José R., Martín, Jesús, Genilloud, Olga, Reyes, Fernando, Díaz, Margarita

“…The co-culturing of microorganisms is a well-known strategy to study microbial interactions in the laboratory. This approach facilitates the identification of…”
Get full text

Identification of the first functional toxin-antitoxin system in Streptomyces by Sevillano, Laura, Díaz, Margarita, Yamaguchi, Yoshihiro, Inouye, Masayori, Santamaría, Ramón I

“…Toxin-antitoxin (TA) systems are widespread among the plasmids and genomes of bacteria and archaea. This work reports the first description of a functional TA…”
Get full text

Scaling technique for prescribed-time output feedback stabilization: Autonomous and non-autonomous paradigms and their comparative study by Orlov, Yury, Verdés Kairuz, Ramón I., Aguilar, Luis T.

“…The present work is of both theoretical and tutorial value. Existing autonomous and non-autonomous paradigms are systematized for prescribed- and…”
Get full text

Mitochondrial Membrane Potential Regulates Nuclear Gene Expression in Macrophages Exposed to Prostaglandin E2 by Sanin, David E., Matsushita, Mai, Klein Geltink, Ramon I., Grzes, Katarzyna M., van Teijlingen Bakker, Nikki, Corrado, Mauro, Kabat, Agnieszka M., Buck, Michael D., Qiu, Jing, Lawless, Simon J., Cameron, Alanna M., Villa, Matteo, Baixauli, Francesc, Patterson, Annette E., Hässler, Fabian, Curtis, Jonathan D., O’Neill, Christina M., O’Sullivan, David, Wu, Duojiao, Mittler, Gerhard, Huang, Stanley Ching-Cheng, Pearce, Erika L., Pearce, Edward J.

“…Metabolic engagement is intrinsic to immune cell function. Prostaglandin E2 (PGE2) has been shown to modulate macrophage activation, yet how PGE2 might affect…”
Get full text

Fixed and Random Effects Selection in Mixed Effects Models by Ibrahim, Joseph G., Zhu, Hongtu, Garcia, Ramon I., Guo, Ruixin

“…We consider selecting both fixed and random effects in a general class of mixed effects models using maximum penalized likelihood (MPL) estimation along with…”
Get full text

Robust observer design with prescribed settling-time bound and finite varying gains by Verdés Kairuz, Ramón I., Orlov, Yury, Aguilar, Luis T.

“…Robust observer design is developed for a normal form system with a prescribed upper bound on the observer convergence time irrespective of initial state…”
Get full text

Applications of Wavelet Transform for Analysis of Harmonic Distortion in Power Systems: A Review by Barros, J., Diego, R. I., de Apraiz, M.

“…Wavelet transform (WT) is one of the most useful digital signal processing tools for time-frequency analysis of power quality disturbances in power systems…”
Get full text

Caught in the cROSsfire: GSH Controls T Cell Metabolic Reprogramming by Klein Geltink, Ramon I., O’Sullivan, David, Pearce, Erika L.

“…T cell activation and proliferation critical for protective immunity depend on appropriate rewiring of cellular metabolism. In this issue of Immunity, Mak…”
Get full text

Alanine supplementation exploits glutamine dependency induced by SMARCA4/2-loss by Zhu, Xianbing, Fu, Zheng, Chen, Shary Y., Ong, Dionzie, Aceto, Giulio, Ho, Rebecca, Steinberger, Jutta, Monast, Anie, Pilon, Virginie, Li, Eunice, Ta, Monica, Ching, Kyle, Adams, Bianca N., Negri, Gian L., Choiniere, Luc, Fu, Lili, Pavlakis, Kitty, Pirrotte, Patrick, Avizonis, Daina Z., Trent, Jeffrey, Weissman, Bernard E., Klein Geltink, Ramon I., Morin, Gregg B., Park, Morag, Huntsman, David G., Foulkes, William D., Wang, Yemin, Huang, Sidong

“…SMARCA4 (BRG1) and SMARCA2 (BRM) are the two paralogous ATPases of the SWI/SNF chromatin remodeling complexes frequently inactivated in cancers. Cells…”
Get full text

Polyamines and eIF5A Hypusination Modulate Mitochondrial Respiration and Macrophage Activation by Puleston, Daniel J., Buck, Michael D., Klein Geltink, Ramon I., Kyle, Ryan L., Caputa, George, O’Sullivan, David, Cameron, Alanna M., Castoldi, Angela, Musa, Yaarub, Kabat, Agnieszka M., Zhang, Ying, Flachsmann, Lea J., Field, Cameron S., Patterson, Annette E., Scherer, Stefanie, Alfei, Francesca, Baixauli, Francesc, Austin, S. Kyle, Kelly, Beth, Matsushita, Mai, Curtis, Jonathan D., Grzes, Katarzyna M., Villa, Matteo, Corrado, Mauro, Sanin, David E., Qiu, Jing, Pällman, Nora, Paz, Katelyn, Maccari, Maria Elena, Blazar, Bruce R., Mittler, Gerhard, Buescher, Joerg M., Zehn, Dietmar, Rospert, Sabine, Pearce, Edward J., Balabanov, Stefan, Pearce, Erika L.

“…How cells adapt metabolism to meet demands is an active area of interest across biology. Among a broad range of functions, the polyamine spermidine is needed…”
Get full text