Search Results - "Ramms, Lena"
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Keratins as the main component for the mechanical integrity of keratinocytes
Published in Proceedings of the National Academy of Sciences - PNAS (12-11-2013)“…Keratins are major components of the epithelial cytoskeleton and are believed to play a vital role for mechanical integrity at the cellular and tissue level…”
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Distinct Impact of Two Keratin Mutations Causing Epidermolysis Bullosa Simplex on Keratinocyte Adhesion and Stiffness
Published in Journal of investigative dermatology (01-10-2015)“…Keratin filaments constitute the major component of the epidermal cytoskeleton from heterodimers of type I and type II keratin subunits. Missense mutations in…”
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Effects of Plectin Depletion on Keratin Network Dynamics and Organization
Published in PloS one (23-03-2016)“…The keratin intermediate filament cytoskeleton protects epithelial cells against various types of stress and is involved in fundamental cellular processes such…”
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Transition of responsive mechanosensitive elements from focal adhesions to adherens junctions on epithelial differentiation
Published in Molecular biology of the cell (15-09-2018)“…The skin's epidermis is a multilayered epithelial tissue and the first line of defense against mechanical stress. Its barrier function depends on an integrated…”
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