Search Results - "Ramirez‐Arcos, Sandra"

Comparable bacterial growth in platelet concentrates suspended in plasma and platelet additive solution and improved detection of bacterial contamination using a new generation automated culture system by Kou, Yuntong, Kumaran, Dilini, Howell, Anita, Ramirez‐Arcos, Sandra

“…Background Microbial screening of platelet concentrates (PC) with automated culture methods is widely implemented to reduce septic transfusion reactions…”
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Cutibacterium acnes contamination does not enhance the proinflammatory profile of platelet concentrates by Kumaran, Dilini, Ramirez‐Arcos, Sandra

“…Background Cutibacterium acnes, a common anaerobic platelet concentrate (PC) contaminant, has been associated with rare mild adverse transfusion reactions and…”
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Nutrient supplementation of culture media improves the detection of Cutibacterium acnes in platelet components by an automated culture system by Kumaran, Dilini, Ramirez‐Arcos, Sandra

“…Abstract Background and Objectives Platelet concentrates (PCs) contaminated with Cutibacterium acnes are often transfused prior to detection by the BACT/ALERT…”
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The international experience of bacterial screen testing of platelet components with automated microbial detection systems: An update by Kamel, Hany, Ramirez‐Arcos, Sandra, McDonald, Carl

“…In 2014, the bacterial subgroup of the Transfusion‐Transmitted Infectious Diseases working party of ISBT published a review on the International Experience of…”
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Contamination of platelet concentrates with Staphylococcus aureus induces significant modulations in platelet functionality by Yousuf, Basit, Pasha, Roya, Pineault, Nicolas, Ramirez‐Arcos, Sandra

“…Background and Objectives Platelet concentrates (PCs) contaminated with Staphylococcus aureus can escape detection during PC screening, causing septic…”
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Proof of concept for detection of staphylococcal enterotoxins in platelet concentrates as a novel safety mitigation strategy by Chi, Sylvia Ighem, Yousuf, Basit, Paredes, Carina, Bearne, Jennifer, McDonald, Carl, Ramirez‐Arcos, Sandra

“…Background and Objectives Staphylococcus aureus is a predominant contaminant of platelet concentrates (PCs) that can evade detection during screening with…”
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Microbiological environmental contamination in the blood supply chain: An international survey by the bacterial subgroup of the ISBT Transfusion‐Transmitted Infectious Diseases Working Party by Ramirez‐Arcos, Sandra, Garcia‐Otalora, Michel, McDonald, Carl

“…Background and Objectives Blood transfusion centres ensure the quality and safety of transfusable blood components. However, septic transfusion reactions…”
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Staphylococcus epidermidis undergoes global changes in gene expression during biofilm maturation in platelet concentrates by Loza‐Correa, Maria, Yousuf, Basit, Ramirez‐Arcos, Sandra

“…Background Staphylococcus epidermidis forms surface‐attached aggregates (biofilms) when grown in platelet concentrates (PCs). Comparative transcriptome…”
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Extension of platelet shelf life with an improved bacterial testing algorithm by Ramirez‐Arcos, Sandra, Evans, Stephanie, McIntyre, Terri, Pang, Christopher, Yi, Qi‐Long, DiFranco, Caesar, Goldman, Mindy

“…Background At Canadian Blood Services, platelet concentrate (PC) shelf life was extended to 7 days with a large‐volume, delayed‐sampling bacterial screening…”
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Fatal false‐negative transfusion infection involving a buffy coat platelet pool contaminated with biofilm‐positive Staphylococcus epidermidis: a case report by Kou, Yuntong, Pagotto, Franco, Hannach, Barbara, Ramirez‐Arcos, Sandra

“…BACKGROUND Bacterial contamination of platelet concentrates (PCs) poses the major posttransfusion infectious risk in developed countries. The aerobic…”
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Evaluation of riboflavin and ultraviolet light treatment against Klebsiella pneumoniae in whole blood‐derived platelets: A pilot study by Alabdullatif, Meshari, Osman, Imad Eldin, Alrasheed, Mai, Ramirez‐Arcos, Sandra, Alyousef, Manal, Althawadi, Sahar, Alhumiadan, Hind

“…Background Bacterial contamination of platelet concentrates (PCs) is the predominant cause of infectious transfusion reactions. The Pathogen Inactivation…”
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Biofilm‐associated accumulation‐associated protein (Aap): A contributing factor to the predominant growth of Staphylococcus epidermidis in platelet concentrates by Alabdullatif, Meshari, Ramirez‐Arcos, Sandra

“…Background and Objectives Staphylococcus epidermidis is a predominant contaminant of platelet concentrates (PCs), outcompeting other skin flora bacteria such…”
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Antimicrobial peptides: an effective approach to prevent bacterial biofilm formation in platelet concentrates by Alabdullatif, Meshari, Atreya, Chintamani D., Ramirez‐Arcos, Sandra

“…BACKGROUND The safety of platelet concentrates (PCs) is a major concern in transfusion medicine due to contamination mainly with skin Gram‐positive bacteria…”
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Current status of rapid bacterial detection methods for platelet components: A 20‐year review by the ISBT Transfusion‐Transmitted Infectious Diseases Working Party Subgroup on Bacteria by Schmidt, Michael, Ramirez‐Arcos, Sandra, Stiller, Lea, McDonald, Carl

“…Background and Objectives Bacterial contamination of platelet components (PCs) poses a safety challenge for transfusion patients. Despite mitigation…”
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Assessment of bacterial growth in leukoreduced cold‐stored whole blood supports overnight hold at room temperature prior to filtration: A pilot study by Ramirez‐Arcos, Sandra, Kou, Yuntong, Kumaran, Dilini, Culibrk, Brankica, Stewart, Tamiko, Schubert, Peter, McTaggart, Ken

“…Background and Objectives Whole blood (WB) transfusion has regained attention to treat trauma patients. We reported no significant changes in in vitro quality…”
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Bacterial survival in whole blood depends on plasma sensitivity and resistance to neutrophil killing by Taha, Mariam, Kyluik‐Price, Dana, Kumaran, Dilini, Scott, Mark D., Toyofuku, Wendy, Ramirez‐Arcos, Sandra

“…BACKGROUND Whole blood (WB) is held at room temperature for not more than 24 hours before blood component manufacturing. The ability of several culture…”
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Development of a proof of principle for universal neutralization of antibiotics in cord blood by‐products used for sterility testing by Kou, Yuntong, Halpenny, Mike, Elmoazzen, Heidi, Ramirez‐Arcos, Sandra

“…BACKGROUND Bacterial contamination of cord blood (CB) represents a safety risk for transplantation patients. CB sterility testing at Canadian Blood Services'…”
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Proliferation of psychrotrophic bacteria in cold‐stored platelet concentrates by Ramirez‐Arcos, Sandra, Kumaran, Dilini, Cap, Andrew, Cardenas, Kristin Michelle, Cloutier, Marc, Ferdin, Justin, Gravemann, Ute, Ketter, Patrick, Landry, Patricia, Lu, Thea, Niekerk, Truscha, Parker, Joel, Renke, Claudia, Seltsam, Axel, Stafford, Bianca, Süssner, Susanne, Vollmer, Tanja, Zilkenat, Susann, McDonald, Carl

“…Background and Objectives Platelet concentrates (PC) are stored at 20–24°C to maintain platelet functionality, which may promote growth of contaminant…”
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Characterization of transfusion-relevant bacteria reference strains in a lyophilized format by Prax, Marcel, McDonald, Carl P, Bekeredjian-Ding, Isabelle, Cloutier, Marc, Gravemann, Ute, Grothaus, Anna, Krut, Oleg, Mpumlwana, Xoliswa, O'Flaherty, Niamh, Satake, Masahiro, Stafford, Bianca, Suessner, Susanne, Vollmer, Tanja, Ramirez-Arcos, Sandra

“…Blood safety measures used by blood establishments to increase blood component safety can be validated using Transfusion-Relevant Bacterial Reference Strains…”
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A suspected septic transfusion reaction associated with posttransfusion contamination of a platelet pool by vancomycin‐resistant Enterococcus faecium by Drews, Steven J., Lesley, Peter, Detsky, Michael E., Distefano, Lanis, Ilagan, Cesario, Mehta, Sangeeta, McGeer, Allison, Shehata, Nadine, Skeate, Robert, Ramirez‐Arcos, Sandra

“…BACKGROUND Vancomycin‐resistant enterococci (VRE) are antibiotic‐resistant organisms associated with both colonization and serious life‐threatening infection…”
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