Search Results - "Ramirez, Marcel I."

Trypanosoma cruzi immune evasion mediated by host cell-derived microvesicles by Cestari, Igor, Ansa-Addo, Ephraim, Deolindo, Poliana, Inal, Jameel M, Ramirez, Marcel I

“…The innate immune system is the first mechanism of vertebrate defense against pathogen infection. In this study, we present evidence for a novel immune evasion…”
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miR-203 secreted in extracellular vesicles mediates the communication between neural crest and placode cells required for trigeminal ganglia formation by Bernardi, Yanel E, Sanchez-Vasquez, Estefania, Márquez, Rocío Belén, Piacentino, Michael L, Urrutia, Hugo, Rossi, Izadora, Alcântara Saraiva, Karina L, Pereira-Neves, Antonio, Ramirez, Marcel I, Bronner, Marianne E, de Miguel, Natalia, Strobl-Mazzulla, Pablo H

“…While interactions between neural crest and placode cells are critical for the proper formation of the trigeminal ganglion, the mechanisms underlying this…”
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Editorial: Tissue Remodeling in Health and Disease Caused by Bacteria, Parasites, Fungi, and Viruses by Lange, Sigrun, Ramirez, Marcel I

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Inefficient complement system clearance of Trypanosoma cruzi metacyclic trypomastigotes enables resistant strains to invade eukaryotic cells by Cestari, Igor, Ramirez, Marcel I

“…The complement system is the main arm of the vertebrate innate immune system against pathogen infection. For the protozoan Trypanosoma cruzi, the causative…”
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Synergistic Effect of Polysaccharides from Chamomile Tea with Nitazoxanide Increases Treatment Efficacy against Giardia intestinalis by Sabatke, Bruna, Chaves, Pedro Felipe P, Cordeiro, Lucimara M C, Ramirez, Marcel I

“…(syn. ) is a protozoa parasite that produces one of the most frequent waterborne causes of diarrhea worldwide. This protozoan infects most mammals, including…”
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Role of early lectin pathway activation in the complement-mediated killing of Trypanosoma cruzi by Cestari, Igor dos S., Krarup, Anders, Sim, Robert B., Inal, Jameel M., Ramirez, Marcel I.

“…The complement system is the first line of defence against pathogen infection and can be activated by the classic, alternative and lectin pathways. Trypanosoma…”
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Characterization of Potent ABCG2 Inhibitor Derived from Chromone: From the Mechanism of Inhibition to Human Extracellular Vesicles for Drug Delivery by Valdameri, Glaucio, Kita, Diogo Henrique, Dutra, Julia de Paula, Gomes, Diego Lima, Tonduru, Arun Kumar, Kronenberger, Thales, Gavinho, Bruno, Rossi, Izadora Volpato, Carvalho, Mariana Mazetto de, Pérès, Basile, Zattoni, Ingrid Fatima, Rego, Fabiane Gomes de Moraes, Picheth, Geraldo, Freitas, Rilton Alves de, Poso, Antti, Ambudkar, Suresh V, Ramirez, Marcel I, Boumendjel, Ahcène, Moure, Vivian Rotuno

“…Inhibition of ABC transporters is a promising approach to overcome multidrug resistance in cancer. Herein, we report the characterization of a potent ABCG2…”
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Involvement of lectin pathway activation in the complement killing of Giardia intestinalis by Evans-Osses, Ingrid, Ansa-Addo, Ephraim A., Inal, Jameel M., Ramirez, Marcel I.

“…Giardia intestinalis (syn. G. lamblia, G. duodenalis) is a flagellated unicellular eukaryotic microorganism that commonly causes diarrheal disease throughout…”
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Guidelines for the purification and characterization of extracellular vesicles of parasites by Fernandez-Becerra, Carmen, Xander, Patrícia, Alfandari, Daniel, Dong, George, Aparici-Herraiz, Iris, Rosenhek-Goldian, Irit, Shokouhy, Mehrdad, Gualdron-Lopez, Melisa, Lozano, Nicholy, Cortes-Serra, Nuria, Karam, Paula Abou, Meneghetti, Paula, Madeira, Rafael Pedro, Porat, Ziv, Soares, Rodrigo Pedro, Costa, Adriana Oliveira, Rafati, Sima, da Silva, Anabela-Cordeiro, Santarém, Nuno, Fernandez-Prada, Christopher, Ramirez, Marcel I, Bernal, Dolores, Marcilla, Antonio, Pereira-Chioccola, Vera Lucia, Alves, Lysangela Ronalte, Portillo, Hernando Del, Regev-Rudzki, Neta, de Almeida, Igor Correia, Schenkman, Sergio, Olivier, Martin, Torrecilhas, Ana Claudia

“…Parasites are responsible for the most neglected tropical diseases, affecting over a billion people worldwide (WHO, 2015) and accounting for billions of cases…”
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The Emerging Role of Complement Lectin Pathway in Trypanosomatids: Molecular Bases in Activation, Genetic Deficiencies, Susceptibility to Infection, and Complement System-Based Therapeutics by Evans-Osses, Ingrid, Ramirez, Marcel I., de Messias-Reason, Iara

“…The innate immune system is evolutionary and ancient and is the pivotal line of the host defense system to protect against invading pathogens and abnormal…”
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Pathogens and extracellular vesicles: New paths and challenges to understanding and treating diseases. Editorial opinion by Ramirez, Marcel I, Marcilla, Antonio

“…Extracellular vesicles (EVs) have been described in all eukaryotic and prokaryotic cells as released membranous structures loaded with biomolecules including…”
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Extracellular vesicles biogenesis and uptake concepts: A comprehensive guide to studying host–pathogen communication by Sabatke, Bruna, Rossi, Izadora Volpato, Sana, Abel, Bonato, Leticia Bassani, Ramirez, Marcel I.

“…Abstract The study of host–pathogen interactions has increased considerably in recent decades. This intercellular communication has been mediated by…”
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Complement C2 Receptor Inhibitor Trispanning Confers an Increased Ability to Resist Complement-Mediated Lysis in Trypanosoma cruzi by Cestari, Igor dos S., Evans-Osses, Ingrid, Freitas, Jualiana, Inal, Jameel M., Ramirez, Marcel I.

“…The ability to resist complement differs between theYand Colombiana Trypanosoma cruzi strains.Wefound that the Y strain of T. cruzi was more able to resist the…”
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Technical challenges of working with extracellular vesicles by Ramirez, Marcel I, Amorim, Maria G, Gadelha, Catarina, Milic, Ivana, Welsh, Joshua A, Freitas, Vanessa M, Nawaz, Muhammad, Akbar, Naveed, Couch, Yvonne, Makin, Laura, Cooke, Fiona, Vettore, Andre L, Batista, Patricia X, Freezor, Roberta, Pezuk, Julia A, Rosa-Fernandes, Lívia, Carreira, Ana Claudia O, Devitt, Andrew, Jacobs, Laura, Silva, Israel T, Coakley, Gillian, Nunes, Diana N, Carter, Dave, Palmisano, Giuseppe, Dias-Neto, Emmanuel

“…Extracellular Vesicles (EVs) are gaining interest as central players in liquid biopsies, with potential applications in diagnosis, prognosis and therapeutic…”
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Unveiling the role of EVs in anaerobic parasitic protozoa by Sabatke, Bruna, Gavinho, Bruno, Coceres, Veronica, de Miguel, Natalia, Ramirez, Marcel I.

“…•Different anaerobic protozoans release extracellular vesicles (EVs).•Protozoa produce EVs that modulate host-parasite interaction.•EVs contribute to…”
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Exosomes or microvesicles? Two kinds of extracellular vesicles with different routes to modify protozoan-host cell interaction by Evans-Osses, Ingrid, Reichembach, Luis H., Ramirez, Marcel I.

“…Parasite-host cell interaction can be modulated by a dynamic communication between extracellular vesicles (EVs). They should play key roles in cell-cell…”
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Microvesicles released from Giardia intestinalis disturb host-pathogen response in vitro by Evans-Osses, Ingrid, Mojoli, Andres, Monguió-Tortajada, Marta, Marcilla, Antonio, Aran, Veronica, Amorim, Maria, Inal, Jameel, Borràs, Francesc E., Ramirez, Marcel I.

“…Giardia intestinalis (G.I), is an anaerobic protozoan and the aetiological agent of giardiasis, a diarrhoea present worldwide and associated with poverty. G.I…”
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A new landscape of host-protozoa interactions involving the extracellular vesicles world by Gavinho, Bruno, Rossi, Izadora Volpato, Evans-Osses, Ingrid, Inal, Jameel, Ramirez, Marcel I

“…Extracellular vesicles (EVs) are released by a wide number of cells including blood cells, immune system cells, tumour cells, adult and embryonic stem cells…”
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VPS32, a member of the ESCRT complex, modulates adherence to host cells in the parasite Trichomonas vaginalis by affecting biogenesis and cargo sorting of released extracellular vesicles by Salas, Nehuén, Coceres, Veronica M., Melo, Tuanne dos Santos, Pereira-Neves, Antonio, Maguire, Vanina G., Rodriguez, Tania M., Sabatke, Bruna, Ramirez, Marcel I., Sha, Jihui, Wohlschlegel, James A., de Miguel, Natalia

“…Trichomonas vaginalis is a common sexually transmitted extracellular parasite that adheres to epithelial cells in the human urogenital tract. Extracellular…”
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Scientific seminars in lockdown: Lessons for a post‐pandemic time in defense of a permanent platform for science dissemination in the world by Sabatke, Bruna, Rossi, Izadora Volpato, Ramirez, Graciela E., Ramirez, Marcel I.

“…In an academic semester, living in social isolation and under restrictions of the pandemic, we organized weekly multidisciplinary seminars from a postgraduate…”
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