Search Results - "Ramirez, Marc"

IAPP-driven metabolic reprogramming induces regression of p53-deficient tumours in vivo by Venkatanarayan, Avinashnarayan, Raulji, Payal, Norton, William, Chakravarti, Deepavali, Coarfa, Cristian, Su, Xiaohua, Sandur, Santosh K., Ramirez, Marc S., Lee, Jaehuk, Kingsley, Charles V., Sananikone, Eliot F., Rajapakshe, Kimal, Naff, Katherine, Parker-Thornburg, Jan, Bankson, James A., Tsai, Kenneth Y., Gunaratne, Preethi H., Flores, Elsa R.

“…p53 is often mutated or lost in cancer; here inactivation of ΔNp63 and ΔNp73 in the absence of p53 is shown to result in metabolic reprogramming and tumour…”
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Allele-Specific Reprogramming of Cancer Metabolism by the Long Non-coding RNA CCAT2 by Redis, Roxana S., Vela, Luz E., Lu, Weiqin, Ferreira de Oliveira, Juliana, Ivan, Cristina, Rodriguez-Aguayo, Cristian, Adamoski, Douglas, Pasculli, Barbara, Taguchi, Ayumu, Chen, Yunyun, Fernandez, Agustin F., Valledor, Luis, Van Roosbroeck, Katrien, Chang, Samuel, Shah, Maitri, Kinnebrew, Garrett, Han, Leng, Atlasi, Yaser, Cheung, Lawrence H., Huang, Gilbert Y., Monroig, Paloma, Ramirez, Marc S., Catela Ivkovic, Tina, Van, Long, Ling, Hui, Gafà, Roberta, Kapitanovic, Sanja, Lanza, Giovanni, Bankson, James A., Huang, Peng, Lai, Stephen Y., Bast, Robert C., Rosenblum, Michael G., Radovich, Milan, Ivan, Mircea, Bartholomeusz, Geoffrey, Liang, Han, Fraga, Mario F., Widger, William R., Hanash, Samir, Berindan-Neagoe, Ioana, Lopez-Berestein, Gabriel, Ambrosio, Andre L.B., Gomes Dias, Sandra M., Calin, George A.

“…Altered energy metabolism is a cancer hallmark as malignant cells tailor their metabolic pathways to meet their energy requirements. Glucose and glutamine are…”
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Evaluation of hyperpolarized [1-¹³C]-pyruvate by magnetic resonance to detect ionizing radiation effects in real time by Sandulache, Vlad C, Chen, Yunyun, Lee, Jaehyuk, Rubinstein, Ashley, Ramirez, Marc S, Skinner, Heath D, Walker, Christopher M, Williams, Michelle D, Tailor, Ramesh, Court, Laurence E, Bankson, James A, Lai, Stephen Y

“…Ionizing radiation (IR) cytotoxicity is primarily mediated through reactive oxygen species (ROS). Since tumor cells neutralize ROS by utilizing reducing…”
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Kinetic Modeling and Constrained Reconstruction of Hyperpolarized [1-13C]-Pyruvate Offers Improved Metabolic Imaging of Tumors by Bankson, James A, Walker, Christopher M, Ramirez, Marc S, Stefan, Wolfgang, Fuentes, David, Merritt, Matthew E, Lee, Jaehyuk, Sandulache, Vlad C, Chen, Yunyun, Phan, Liem, Chou, Ping-Chieh, Rao, Arvind, Yeung, Sai-Ching J, Lee, Mong-Hong, Schellingerhout, Dawid, Conrad, Charles A, Malloy, Craig, Sherry, A Dean, Lai, Stephen Y, Hazle, John D

“…Hyperpolarized [1-(13)C]-pyruvate has shown tremendous promise as an agent for imaging tumor metabolism with unprecedented sensitivity and specificity. Imaging…”
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Hypoxia-Activated Prodrug TH-302 Targets Hypoxic Bone Marrow Niches in Preclinical Leukemia Models by Benito, Juliana, Ramirez, Marc S, Millward, Niki Zacharias, Velez, Juliana, Harutyunyan, Karine G, Lu, Hongbo, Shi, Yue-Xi, Matre, Polina, Jacamo, Rodrigo, Ma, Helen, Konoplev, Sergej, McQueen, Teresa, Volgin, Andrei, Protopopova, Marina, Mu, Hong, Lee, Jaehyuk, Bhattacharya, Pratip K, Marszalek, Joseph R, Davis, R Eric, Bankson, James A, Cortes, Jorge E, Hart, Charles P, Andreeff, Michael, Konopleva, Marina

“…To characterize the prevalence of hypoxia in the leukemic bone marrow, its association with metabolic and transcriptional changes in the leukemic blasts and…”
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A catalyzing phantom for reproducible dynamic conversion of hyperpolarized [1-¹³C]-pyruvate by Walker, Christopher M, Lee, Jaehyuk, Ramirez, Marc S, Schellingerhout, Dawid, Millward, Steven, Bankson, James A

“…In vivo real time spectroscopic imaging of hyperpolarized ¹³C labeled metabolites shows substantial promise for the assessment of physiological processes that…”
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Allele-Specific Reprogramming of Cancer Metabolism by the Long Non-coding RNA CCAT2 by Redis, Roxana S., Vela, Luz E., Lu, Weiqin, Ferreira de Oliveira, Juliana, Ivan, Cristina, Rodriguez-Aguayo, Cristian, Adamoski, Douglas, Pasculli, Barbara, Taguchi, Ayumu, Chen, Yunyun, Fernandez, Agustin F., Valledor, Luis, Van Roosbroeck, Katrien, Chang, Samuel, Shah, Maitri, Kinnebrew, Garrett, Han, Leng, Atlasi, Yaser, Cheung, Lawrence H., Huang, Gilbert Y., Monroig, Paloma, Ramirez, Marc S., Catela Ivkovic, Tina, Van, Long, Ling, Hui, Gafà, Roberta, Kapitanovic, Sanja, Lanza, Giovanni, Bankson, James A., Huang, Peng, Lai, Stephen Y., Bast, Robert C., Rosenblum, Michael G., Radovich, Milan, Ivan, Mircea, Bartholomeusz, Geoffrey, Liang, Han, Fraga, Mario F., Widger, William R., Hanash, Samir, Berindan-Neagoe, Ioana, Lopez-Berestein, Gabriel, Ambrosio, Andre L.B., Gomes Dias, Sandra M., Calin, George A.

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Radial spectroscopic MRI of hyperpolarized [1-13C] pyruvate at 7 tesla by Ramirez, Marc S., Lee, Jaehyuk, Walker, Christopher M., Sandulache, Vlad C., Hennel, Franciszek, Lai, Stephen Y., Bankson, James A.

“…Purpose The transient and nonrenewable signal from hyperpolarized metabolites necessitates extensive sequence optimization for encoding spatial, spectral, and…”
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High-throughput hyperpolarized (13)C metabolic investigations using a multi-channel acquisition system by Lee, Jaehyuk, Ramirez, Marc S, Walker, Christopher M, Chen, Yunyun, Yi, Stacey, Sandulache, Vlad C, Lai, Stephen Y, Bankson, James A

“…Magnetic resonance imaging and spectroscopy of hyperpolarized (HP) compounds such as [1-(13)C]-pyruvate have shown tremendous potential for offering new…”
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Multiple-mouse MRI with multiple arrays of receive coils by Ramirez, Marc S., Esparza-Coss, Emilio, Bankson, James A.

“…Compared to traditional single‐animal imaging methods, multiple‐mouse MRI has been shown to dramatically improve imaging throughput and reduce the potentially…”
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Feasibility of multianimal hyperpolarized (13) C MRS by Ramirez, Marc S, Lee, Jaehyuk, Walker, Christopher M, Chen, Yunyun, Kingsley, Charles V, De La Cerda, Jorge, Maldonado, Kiersten L, Lai, Stephen Y, Bankson, James A

“…There is great potential for real-time investigation of metabolism with MRS and hyperpolarized (HP) (13) C agents. Unfortunately, HP technology has high…”
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A throughput-optimized array system for multiple-mouse MRI by Ramirez, Marc S., Lai, Stephen Y., Bankson, James A.

“…MRI is a versatile tool for the systematic assessment of anatomical and functional changes in small‐animal models of human disease. Its noninvasive nature…”
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Feasibility of multianimal hyperpolarized 13C MRS by Ramirez, Marc S., Lee, Jaehyuk, Walker, Christopher M., Chen, Yunyun, Kingsley, Charles V., De La Cerda, Jorge, Maldonado, Kiersten L., Lai, Stephen Y., Bankson, James A.

“…Purpose There is great potential for real‐time investigation of metabolism with MRS and hyperpolarized (HP) 13C agents. Unfortunately, HP technology has high…”
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Wireless self-gated multiple-mouse cardiac cine MRI by Esparza-Coss, Emilio, Ramirez, Marc S., Bankson, James A.

“…Despite the excellent image‐contrast capability of MRI and the ability to synchronize MRI with the murine cardiac cycle, this technique is underused for…”
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A practical method for 2D multiple-animal MRI by Ramirez, Marc S., Bankson, James A.

“…Purpose To investigate practical methods for achieving routine simultaneous 2D MRI of multiple animals in large‐bore experimental scanners. Materials and…”
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Feasibility of multiple-mouse dynamic contrast-enhanced MRI by Ramirez, Marc S., Ragan, Dustin K., Kundra, Vikas, Bankson, James A.

“…Dynamic contrast‐enhanced (DCE‐) MRI is often used to evaluate the response to experimental antiangiogenic therapies in small animal models of cancer…”
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Monitoring Histone Deacetylase Inhibition In Vivo: Noninvasive Magnetic Resonance Spectroscopy Method by Sankaranarayanapillai, Madhuri, Tong, William P., Yuan, Qing, Bankson, James A., Dafni, Hagit, Bornmann, William G., Soghomonyan, Suren, Pal, Ashutosh, Ramirez, Marc S., Webb, Douglas, Kaluarachchi, Kumaralal, Gelovani, Juri G., Ronen, Sabrina M.

“…Histone deacetylase inhibitors (HDACis) are emerging as promising and selective antitumor agents. However, HDACis can lead to tumor stasis rather than…”
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Sonogenetics: Non-invasive cellular manipulation using ultrasound by Vasan, Aditya, Magaram, Uri, Lee-Kubli, Corinne, Tufail, Yusuf, Mendoza, Jose, Ramirez, Marc, Weiss, Connor, Chalasani, Sreekanth, Friend, James

“…Optogenetics has been an important tool used in manipulating different cell types, understanding various diseases and has recently been studied as an…”
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The cell cycle regulator 14-3-3σ opposes and reverses cancer metabolic reprogramming by Phan, Liem, Chou, Ping-Chieh, Velazquez-Torres, Guermarie, Samudio, Ismael, Parreno, Kenneth, Huang, Yaling, Tseng, Chieh, Vu, Thuy, Gully, Chris, Su, Chun-Hui, Wang, Edward, Chen, Jian, Choi, Hyun-Ho, Fuentes-Mattei, Enrique, Shin, Ji-Hyun, Shiang, Christine, Grabiner, Brian, Blonska, Marzenna, Skerl, Stephen, Shao, Yiping, Cody, Dianna, Delacerda, Jorge, Kingsley, Charles, Webb, Douglas, Carlock, Colin, Zhou, Zhongguo, Hsieh, Yun-Chih, Lee, Jaehyuk, Elliott, Andrew, Ramirez, Marc, Bankson, Jim, Hazle, John, Wang, Yongxing, Li, Lei, Weng, Shaofan, Rizk, Nibal, Wen, Yu Ye, Lin, Xin, Wang, Hua, Wang, Huamin, Zhang, Aijun, Xia, Xuefeng, Wu, Yun, Habra, Mouhammed, Yang, Wei, Pusztai, Lajos, Yeung, Sai-Ching, Lee, Mong-Hong

“…Extensive reprogramming of cellular energy metabolism is a hallmark of cancer. Despite its importance, the molecular mechanism controlling this tumour…”
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Abstract B07: Using magnetic resonance and hyperpolarized tracers to monitor solid tumor progression, metastasis, and response to treatment by Sandulache, Vlad, Chen, Yunyun, Lee, Jaehyuk, Ramirez, Marc, Skinner, Heath, Court, Laurence, Bankson, Jim, Lai, Stephen

“…Abstract Purpose: To optimize translational fidelity of a murine model of anaplastic thyroid carcinoma (ATC) using real-time metabolic imaging. Background:…”
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