Search Results - "Ramirez, Christina M"

An evidence review of face masks against COVID-19 by Howard, Jeremy, Huang, Austin, Li, Zhiyuan, Tufekci, Zeynep, Zdimal, Vladimir, van der Westhuizen, Helene-Mari, von Delft, Arne, Price, Amy, Fridman, Lex, Tang, Lei-Han, Tang, Viola, Watson, Gregory L., Bax, Christina E., Shaikh, Reshama, Questier, Frederik, Hernandez, Danny, Chu, Larry F., Ramirez, Christina M., Rimoin, Anne W.

“…The science around the use of masks by the public to impede COVID-19 transmission is advancing rapidly. In this narrative review, we develop an analytical…”
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Magnesium decreases inflammatory cytokine production: a novel innate immunomodulatory mechanism by Sugimoto, Jun, Romani, Andrea M, Valentin-Torres, Alice M, Luciano, Angel A, Ramirez Kitchen, Christina M, Funderburg, Nicholas, Mesiano, Sam, Bernstein, Helene B

“…MgSO(4) exposure before preterm birth is neuroprotective, reducing the risk of cerebral palsy and major motor dysfunction. Neonatal inflammatory cytokine…”
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SARS‐CoV‐2 worldwide replication drives rapid rise and selection of mutations across the viral genome: a time‐course study – potential challenge for vaccines and therapies by Weber, Stefanie, Ramirez, Christina M, Weiser, Barbara, Burger, Harold, Doerfler, Walter

“…Scientists and the public were alarmed at the first large viral variant of SARS‐CoV‐2 reported in December 2020. We have followed the time course of emerging…”
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Acute antagonism in three-drug combinations for vaginal HIV prevention in humanized mice by Gallay, Philippe A., Ramirez, Christina M., Baum, Marc M.

“…Adolescent girls and young women in low- to middle-income countries are disproportionately at risk of becoming HIV-1 infected. New non-vaccine biomedical…”
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Pandemic velocity: Forecasting COVID-19 in the US with a machine learning & Bayesian time series compartmental model by Watson, Gregory L, Xiong, Di, Zhang, Lu, Zoller, Joseph A, Shamshoian, John, Sundin, Phillip, Bufford, Teresa, Rimoin, Anne W, Suchard, Marc A, Ramirez, Christina M

“…Predictions of COVID-19 case growth and mortality are critical to the decisions of political leaders, businesses, and individuals grappling with the pandemic…”
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Reasons for undergoing amyloid imaging among diverse enrollees in the A4 study by Magana‐Ramirez, Christina M., Irizarry‐Martinez, Gimarie, Gillen, Daniel L., Grill, Joshua D.

“…INTRODUCTION Understanding attitudes toward participation among diverse preclinical Alzheimer's disease (AD) trial participants could yield insights to…”
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In vivo activation of latent HIV with a synthetic bryostatin analog effects both latent cell "kick" and "kill" in strategy for virus eradication by Marsden, Matthew D, Loy, Brian A, Wu, Xiaomeng, Ramirez, Christina M, Schrier, Adam J, Murray, Danielle, Shimizu, Akira, Ryckbosch, Steven M, Near, Katherine E, Chun, Tae-Wook, Wender, Paul A, Zack, Jerome A

“…The ability of HIV to establish a long-lived latent infection within resting CD4+ T cells leads to persistence and episodic resupply of the virus in patients…”
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Ubiquitous Micro-Modular Homologies among Genomes from Viruses to Bacteria to Human Mitochondrial DNA: Platforms for Recombination during Evolution? by Weber, Stefanie, Ramirez, Christina M, Doerfler, Walter

“…The emerging Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) and its variants have raised tantalizing questions about evolutionary mechanisms that…”
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Increased Rate of Epigenetic Aging in Men Living With HIV Prior to Treatment by Sehl, Mary E, Breen, Elizabeth Crabb, Shih, Roger, Chen, Larry, Wang, Ruibin, Horvath, Steve, Bream, Jay H, Duggal, Priya, Martinson, Jeremy, Wolinsky, Steven M, Martinez-Maza, Otoniel, Ramirez, Christina M, Jamieson, Beth D

“…Epigenetic aging is accelerated in tissues of persons living with HIV (PLWH) and may underlie the early onset of age-related illnesses. This study examines the…”
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The combination of the NS5A and cyclophilin inhibitors results in an additive anti-HCV inhibition in humanized mice without development of resistance by Bobardt, Michael, Ramirez, Christina M, Baum, Marc M, Ure, Daren, Foster, Robert, Gallay, Philippe A

“…We and others previously reported that the direct-acting agents (DAA) NS5A inhibitors (NS5Ai) and the host-targeting agents cyclophilin inhibitors (CypIs)…”
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Characterization of designed, synthetically accessible bryostatin analog HIV latency reversing agents by Marsden, Matthew D., Wu, Xiaomeng, Navab, Sara M., Loy, Brian A., Schrier, Adam J., DeChristopher, Brian A., Shimizu, Akira J., Hardman, Clayton T., Ho, Stephen, Ramirez, Christina M., Wender, Paul A., Zack, Jerome A.

“…HIV latency in resting CD4+ T cell represents a key barrier preventing cure of the infection with antiretroviral drugs alone. Latency reversing agents (LRAs)…”
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Telomerase-Based Pharmacologic Enhancement of Antiviral Function of Human CD8+ T Lymphocytes by Fauce, Steven Russell, Jamieson, Beth D, Chin, Allison C, Mitsuyasu, Ronald T, Parish, Stan T, Ng, Hwee L, Ramirez Kitchen, Christina M, Yang, Otto O, Harley, Calvin B, Effros, Rita B

“…Telomerase reverse transcribes telomere DNA onto the ends of linear chromosomes and retards cellular aging. In contrast to most normal somatic cells, which…”
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Distinct aging profiles of CD8+ T cells in blood versus gastrointestinal mucosal compartments by Dock, Jeffrey, Ramirez, Christina M, Hultin, Lance, Hausner, Mary Ann, Hultin, Patricia, Elliott, Julie, Yang, Otto O, Anton, Peter A, Jamieson, Beth D, Effros, Rita B

“…A hallmark of human immunosenescence is the accumulation of late-differentiated memory CD8+ T cells with features of replicative senescence, such as inability…”
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Accelerated aging in HIV/AIDS: novel biomarkers of senescent human CD8+ T cells by Chou, Jennifer P, Ramirez, Christina M, Wu, Jennifer E, Effros, Rita B

“…Clinical evaluation of immune reconstitution and health status during HIV-1 infection and anti-retroviral therapy (ART) is largely based on CD4+ T cell counts…”
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Prostaglandin E2 promotes features of replicative senescence in chronically activated human CD8+ T cells by Chou, Jennifer P, Ramirez, Christina M, Ryba, Danielle M, Koduri, Megha P, Effros, Rita B

“…Prostaglandin E2 (PGE2), a pleiotropic immunomodulatory molecule, and its free radical catalyzed isoform, iso-PGE2, are frequently elevated in the context of…”
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Stable DNA Methylation Boundaries and Expanded Trinucleotide Repeats: Role of DNA Insertions by Naumann, Anja, Kraus, Cornelia, Hoogeveen, André, Ramirez, Christina M., Doerfler, Walter

“…The human genome segment upstream of the FMR1 (fragile X mental retardation 1) gene (Xq27.3) contains several genetic signals, among them is a DNA methylation…”
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Misperceptions of COVID-19 illness risk and preferences for business and school closures in the United States by Ladapo, Joseph A., Rothwell, Jonathan T., Ramirez, Christina M.

“…Misperceptions about COVID-19 health risks may be associated with preferences for school and business closures and fear of becoming seriously ill. We analyzed…”
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Pseudo-likelihood based logistic regression for estimating COVID-19 infection and case fatality rates by gender, race, and age in California by Xiong, Di, Zhang, Lu, Watson, Gregory L., Sundin, Phillip, Bufford, Teresa, Zoller, Joseph A., Shamshoian, John, Suchard, Marc A., Ramirez, Christina M.

“…In emerging epidemics, early estimates of key epidemiological characteristics of the disease are critical for guiding public policy. In particular, identifying…”
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Association of COVID-19 Risk Misperceptions With Household Isolation in the United States: Survey Study by Ladapo, Joseph A, Rothwell, Jonathan T, Ramirez, Christina M

“…Background Adverse mental and emotional health outcomes are increasingly recognized as a public health challenge associated with the COVID-19 pandemic…”
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Decreased but persistent epigenetic age acceleration is associated with changes in T-cell subsets after initiation of highly active antiretroviral therapy in persons living with HIV by Sehl, Mary E, Breen, Elizabeth Crabb, Shih, Roger, Li, Fengxue, Zhang, Joshua, Langfelder, Peter, Horvath, Steve, Bream, Jay H, Duggal, Priya, Martinson, Jeremy, Wolinsky, Steven M, Martinez-Maza, Otoniel, Ramirez, Christina M, Jamieson, Beth D

“…Persons living with HIV (PLWH) experience the early onset of age-related illnesses, even in the setting of successful human immunodeficiency virus (HIV)…”
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