Search Results - "Ramirez, Cherie L."
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A Synthetic Biology Framework for Programming Eukaryotic Transcription Functions
Published in Cell (03-08-2012)“…Eukaryotic transcription factors (TFs) perform complex and combinatorial functions within transcriptional networks. Here, we present a synthetic framework for…”
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Revealing off-target cleavage specificities of zinc-finger nucleases by in vitro selection
Published in Nature methods (01-09-2011)“…An in vitro method for examining cleavage patterns of zinc-finger nucleases (ZFNs) identifies previously unknown off-target cleavage sites. Some of the sites…”
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Improved somatic mutagenesis in zebrafish using transcription activator-like effector nucleases (TALENs)
Published in PloS one (24-05-2012)“…Zinc Finger Nucleases (ZFNs) made by Context-Dependent Assembly (CoDA) and Transcription Activator-Like Effector Nucleases (TALENs) provide robust and…”
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In Situ Genetic Correction of the Sickle Cell Anemia Mutation in Human Induced Pluripotent Stem Cells Using Engineered Zinc Finger Nucleases
Published in Stem cells (Dayton, Ohio) (01-11-2011)“…The combination of induced pluripotent stem cell (iPSC) technology and targeted gene modification by homologous recombination (HR) represents a promising new…”
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Unexpected failure rates for modular assembly of engineered zinc fingers
Published in Nature methods (01-05-2008)Get full text
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In silico abstraction of zinc finger nuclease cleavage profiles reveals an expanded landscape of off-target sites
Published in Nucleic acids research (01-10-2013)“…Gene-editing nucleases enable targeted modification of DNA sequences in living cells, thereby facilitating efficient knockout and precise editing of endogenous…”
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Engineered zinc finger nickases induce homology-directed repair with reduced mutagenic effects
Published in Nucleic acids research (01-07-2012)“…Engineered zinc finger nucleases (ZFNs) induce DNA double-strand breaks at specific recognition sequences and can promote efficient introduction of desired…”
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Assessment of the Role of Niacin in Managing Cardiovascular Disease Outcomes: A Systematic Review and Meta-analysis
Published in JAMA network open (05-04-2019)“…Niacin remains a therapeutic option for patients with cardiovascular disease, but recent studies have called into question the effectiveness of other drugs…”
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Dispelling myths about drug procurement policy
Published in The Lancet global health (01-06-2018)Get full text
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10
Public health 101 nanocourse: a condensed educational tool for non-public health professionals
Published in American journal of public health (1971) (01-03-2015)“…Graduate students and postdoctoral fellows-including those at the Harvard School of Public Health (HSPH)-have somewhat limited opportunities outside of…”
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The dynamics and tuning of orchestral crotales
Published in The Journal of the Acoustical Society of America (01-10-2004)“…An experimental and theoretical investigation of the acoustic and vibrational properties of orchestral crotales within the range C6 to C8 is reported…”
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Erratum: Unexpected failure rates for modular assembly of engineered zinc fingers
Published in Nature methods (01-06-2008)“…Nat. Methods 5, 374–375 (2008); corrected after print 29 May 2008. In the version of this correspondence initially published, the two previously published…”
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