Search Results - "Ramires Júnior, Osmar Vieira"

Effects of methylphenidate on mitochondrial dynamics and bioenergetics in the prefrontal cortex of juvenile rats are sex-dependent by Rieder, Alessandra Schmitt, Ramires Júnior, Osmar Vieira, Prauchner, Gustavo Ricardo Krupp, Wyse, Angela T.S.

“…Methylphenidate (MPH) is a central nervous system stimulant drug and a first order prescription in the treatment of Attention Deficit Hyperactivity Disorder…”
Get full text

Folic acid supplementation during pregnancy alters behavior in male rat offspring: nitrative stress and neuroinflammatory implications by Silveira, Josiane Silva, Ramires Júnior, Osmar Vieira, Schmitz, Felipe, Ferreira, Fernanda Silva, Rodrigues, Fabiana Cristina, Silva, Robson Coutinho, Savio, Luiz Eduardo Baggio, Wyse, Angela T. S.

“…Pregnancy diet can impact offspring’s neurodevelopment, metabolism, redox homeostasis, and inflammatory status. In pregnancy, folate demand is increased due to…”
Get full text

Multimarker approach to assess the exposure of the wild rodent Calomys laucha to a simulated crude oil spill by de Almeida, Krissia Aparecida, Garcia, Edariane Menestrino, Penteado, Julia Oliveira, Tavella, Ronan Adler, Fernandes, Caroline Lopes Feijo, Ramires, Paula Florencio, Ramires Júnior, Osmar Vieira, Muccillo-Baisch, Ana Luíza, da Luz Mathias, Maria, Dias, Deodália, da Siva Júnior, Flavio Manoel Rodrigues

“…A mysterious oil spill occurred in the ocean near Brazil in 2019, which affected coastal areas in northeastern Brazil. When oil pollution occurs in coastal…”
Get full text

Nanoemulsion Improves the Neuroprotective Effects of Curcumin in an Experimental Model of Parkinson’s Disease by Ramires Júnior, Osmar Vieira, Alves, Barbara da Silva, Barros, Paula Alice Bezerra, Rodrigues, Jamile Lima, Ferreira, Shana Pires, Monteiro, Linda Karolynne Seregni, Araújo, Gabriela de Moraes Soares, Fernandes, Sara Silva, Vaz, Gustavo Richter, Dora, Cristiana Lima, Hort, Mariana Appel

“…Parkinson’s disease (PD) is a neurodegenerative disorder characterized by motor dysfunction. Recent studies have shown that curcumin (CUR) has neuroprotective…”
Get full text

Hyperhomocysteinemia alters cytokine gene expression, cytochrome c oxidase activity and oxidative stress in striatum and cerebellum of rodents by dos Santos, Tiago Marcon, Ramires Júnior, Osmar Vieira, Alves, Vinícius Santos, Coutinho-Silva, Robson, Savio, Luiz Eduardo Baggio, Wyse, Angela T.S.

“…Homocysteine has been linked to neurodegeneration and motor function impairments. In the present study, we evaluate the effect of chronic mild…”
Get full text

Homocysteine May Decrease Glucose Uptake and Alter the Akt/GSK3β/GLUT1 Signaling Pathway in Hippocampal Slices: Neuroprotective Effects of Rivastigmine and Ibuprofen by Ramires Júnior, Osmar Vieira, Silveira, Josiane Silva, dos Santos, Tiago Marcon, Ferreira, Fernanda Silva, Vizuete, Adriana Fernanda K., Gonçalves, Carlos Alberto, Wyse, Angela T. S.

“…Homocysteine (Hcy) is a risk factor for neurodegenerative diseases, such as Alzheimer’s Disease, and is related to cellular and tissue damage. In the present…”
Get full text

In vivo toxicity evaluation of nanoemulsions for drug delivery by Hort, Mariana Appel, Alves, Barbara da Silva, Ramires Júnior, Osmar Vieira, Falkembach, Mariana Correa, Araújo, Gabriela de Moraes Soares, Fernandes, Caroline Lopes Feijo, Tavella, Ronan Adler, Bidone, Juliana, Dora, Cristiana Lima, da Silva Júnior, Flavio Manoel Rodrigues

“…Lipid nanocarriers (LNs), for example nanoemulsions (NE), are an emerging tool for drug delivery due to their ability to incorporate drugs, protect the drug…”
Get full text

Effects of curcumin and fish oil on motor behavior and biochemical parameters in mice exposed to rotenone by Alves, Barbara da Silva, Cunha, Andre Brito da, Barros, Paula Alice Bezerra, Monteiro, Linda Karolynne Seregni, Abrao, Lian da Costa, Araujo, Gabriela de Moraes Soares, de Miranda, Fernanda Barros, Ramires, Osmar Vieira, Jr, Silva, Dennis Guilherme da Costa, Arbo, Bruno Dutra, Dora, Cristiana Lima, Hort, Mariana Appel

“…Parkinson's disease is characterized by dopaminergic neuronal loss, mainly in the substantia nigra pars compacta. Currently, pharmacological treatment reduces…”
Get full text

High-protein nutrition during pregnancy increases neuroinflammation and homocysteine levels and impairs behavior in male adolescent rats offspring by Silveira, Josiane Silva, Júnior, Osmar Vieira Ramires, Schmitz, Felipe, Ferreira, Fernanda Silva, Rodrigues, Fabiana Cristina, Deon, Marion, Ribas, Graziella, Coutinho-Silva, Robson, Vargas, Carmen Regla, Savio, Luiz Eduardo Baggio, Wyse, Angela T.S.

Get full text

Zika Virus affects neurobehavioral development, and causes oxidative stress associated to blood–brain barrier disruption in a rat model of congenital infection by de Almeida, Wellington, Deniz, Bruna Ferrary, Souza dos Santos, Adriana, Faustino, Aline Martins, Ramires Junior, Osmar Vieira, Schmitz, Felipe, Varela, Ana Paula Muterle, Teixeira, Thais Fumaco, Sesterheim, Patrícia, Marques da Silva, Fernanda, Roehe, Paulo Michel, Wyse, Angela TS, Pereira, Lenir Orlandi

“…•Congenital Zika virus infection caused offspring’s neurobehavioral development delay.•Gestational Zika virus damaged the offspring’s blood–brain…”
Get full text

LDL Exposure Disrupts Mitochondrial Function and Dynamics in a Hippocampal Neuronal Cell Line by Farias, Hémelin Resende, Ramos, Jessica Marques Obelar, Griesang, Caroline Tainá, Santos, Lucas, Junior, Osmar Vieira Ramires, Souza, Debora Guerini, Ferreira, Fernanda Silva, Somacal, Sabrina, Martins, Leo Anderson Meira, de Souza, Diogo Onofre Gomes, Moreira, José Cláudio Fonseca, Wyse, Angela T S, Guma, Fátima Theresinha Costa Rodrigues, de Oliveira, Jade

“…Hypercholesterolemia has been associated with cognitive dysfunction and neurodegenerative diseases. Moreover, this metabolic condition disrupts the blood-brain…”
Get full text

Effect of Quinolinic Acid on Behavior, Morphology, and Expression of Inflammatory/oxidative Status in Rats’ Striatum: Is Coenzyme Q10 a Good Protector? by Ferreira, Fernanda Silva, Junior, Osmar Vieira Ramires, dos Santos, Tiago Marcon, Silveira, Josiane Silva, Deniz, Bruna Ferrary, Alves, Vinícius Santos, Coutinho-Silva, Robson, Savio, Luiz Eduardo Baggio, Wyse, Angela T. S.

“…Quinolinic acid (QUIN) is a toxic compound with pro-oxidant, pro-inflammatory, and pro-apoptotic actions found at high levels in the central nervous system…”
Get full text

Targeting glycolysis for neuroprotection in early LPS-induced neuroinflammation by Vizuete, Adriana Fernanda K., Fróes, Fernanda, Seady, Marina, Caurio, Aline Castro, Ramires Junior, Osmar Vieira, Leite, Ana Karla Oliveira, Farias, Clarissa Penha, Wyse, Angela T.S., Gonçalves, Carlos-Alberto

“…Neuroinflammation is a pathophysiological feature of numerous neurological and psychiatric disorders. The immune response in the central nervous system, driven…”
Get full text

Homocysteine decreases VEGF, EGF, and TrkB levels and increases CCL5/RANTES in the hippocampus: Neuroprotective effects of rivastigmine and ibuprofen by Ramires Júnior, Osmar Vieira, Silveira, Josiane Silva, Gusso, Darlan, Krupp Prauchner, Gustavo Ricardo, Ferrary Deniz, Bruna, Almeida, Wellington de, Pereira, Lenir Orlandi, Wyse, Angela TS

“…Homocysteine (Hcy) is produced through methionine transmethylation. Elevated Hcy levels are termed Hyperhomocysteinemia (HHcy) and represent a risk factor for…”
Get full text

Mild hyperhomocysteinemia alters oxidative stress profile via Nrf2, inflammation and cholinesterases in cardiovascular system of aged male rats by Prauchner, Gustavo Ricardo Krupp, Ramires Junior, Osmar Vieira, Rieder, Alessandra Schmitt, Wyse, Angela T.S.

“…Homocysteine (Hcy) is an independent cardiovascular disease (CVD) risk factor, whose mechanisms are poorly understood. We aimed to explore mild…”
Get full text

Rivastigmine Reverses the Decrease in Synapsin and Memory Caused by Homocysteine: Is There Relation to Inflammation? by Ramires Junior, Osmar Vieira, dos Santos, Tiago Marcon, Silveira, Josiane Silva, Leite-Aguiar, Raíssa, Coutinho-Silva, Robson, Savio, Luiz Eduardo Baggio, Wyse, Angela T. S.

“…Elevated levels of homocysteine (Hcy) in the blood, called hyperhomocysteinemia (HHcy), is a prevalent risk factor for it has been shown that Hcy induces…”
Get full text

Quinolinic Acid Impairs Redox Homeostasis, Bioenergetic, and Cell Signaling in Rat Striatum Slices: Prevention by Coenzyme Q10 by Ferreira, Fernanda Silva, Dos Santos, Tiago Marcon, Ramires Junior, Osmar Vieira, Silveira, Josiane Silva, Schmitz, Felipe, Wyse, Angela T. S.

“…Quinolinic acid (QUIN) is an important agonist of NMDA receptors that are found at high levels in cases of brain injury and neuroinflammation. Therefore, it is…”
Get full text

Methylphenidate Exposing During Neurodevelopment Alters Amino Acid Profile, Astrocyte Marker and Glutamatergic Excitotoxicity in the Rat Striatum by Schmitz, Felipe, Durán-Carabali, Luz Elena, Rieder, Alessandra Schmitt, Silveira, Josiane S., Ramires Junior, Osmar Vieira, Bobermin, Larissa D., Quincozes-Santos, André, Alves, Vinícius S., Coutinho-Silva, Robson, Savio, Luiz Eduardo B., Coelho, Daniella M., Vargas, Carmen R., Netto, Carlos Alexandre, Wyse, Angela T. S.

“…There is a public health concern about the use of methylphenidate (MPH) since the higher prescription for young individuals and non-clinical purposes is…”
Get full text

Quinolinic Acid Impairs Redox Homeostasis, Bioenergetic, and Cell Signaling in Rat Striatum Slices: Prevention by Coenzyme Q 10 by Ferreira, Fernanda Silva, Dos Santos, Tiago Marcon, Ramires Junior, Osmar Vieira, Silveira, Josiane Silva, Schmitz, Felipe, Wyse, Angela T S

“…Quinolinic acid (QUIN) is an important agonist of NMDA receptors that are found at high levels in cases of brain injury and neuroinflammation. Therefore, it is…”
Get full text

Effect of Quinolinic Acid on Behavior, Morphology, and Expression of Inflammatory/oxidative Status in Rats' Striatum: Is Coenzyme Q 10 a Good Protector? by Ferreira, Fernanda Silva, Junior, Osmar Vieira Ramires, Dos Santos, Tiago Marcon, Silveira, Josiane Silva, Deniz, Bruna Ferrary, Alves, Vinícius Santos, Coutinho-Silva, Robson, Savio, Luiz Eduardo Baggio, Wyse, Angela T S

“…Quinolinic acid (QUIN) is a toxic compound with pro-oxidant, pro-inflammatory, and pro-apoptotic actions found at high levels in the central nervous system…”
Get full text