Search Results - "Ramin, S"

Radiation and dual checkpoint blockade activate non-redundant immune mechanisms in cancer by Twyman-Saint Victor, Christina, Rech, Andrew J., Maity, Amit, Rengan, Ramesh, Pauken, Kristen E., Stelekati, Erietta, Benci, Joseph L., Xu, Bihui, Dada, Hannah, Odorizzi, Pamela M., Herati, Ramin S., Mansfield, Kathleen D., Patsch, Dana, Amaravadi, Ravi K., Schuchter, Lynn M., Ishwaran, Hemant, Mick, Rosemarie, Pryma, Daniel A., Xu, Xiaowei, Feldman, Michael D., Gangadhar, Tara C., Hahn, Stephen M., Wherry, E. John, Vonderheide, Robert H., Minn, Andy J.

“…In this study, involving melanoma patients and a mouse model for melanoma, an optimal anti-tumour response was induced by using a combination of radiation with…”
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Evaluation of Immune Response and Disease Status in Systemic Lupus Erythematosus Patients Following SARS–CoV‐2 Vaccination by Izmirly, Peter M., Kim, Mimi Y., Samanovic, Marie, Fernandez‐Ruiz, Ruth, Ohana, Sharon, Deonaraine, Kristina K., Engel, Alexis J., Masson, Mala, Xie, Xianhong, Cornelius, Amber R., Herati, Ramin S., Haberman, Rebecca H., Scher, Jose U., Guttmann, Allison, Blank, Rebecca B., Plotz, Benjamin, Haj‐Ali, Mayce, Banbury, Brittany, Stream, Sara, Hasan, Ghadeer, Ho, Gary, Rackoff, Paula, Blazer, Ashira D., Tseng, Chung‐E, Belmont, H. Michael, Saxena, Amit, Mulligan, Mark J., Clancy, Robert M., Buyon, Jill P.

“…Objective To evaluate seroreactivity and disease flares after COVID‐19 vaccination in a multiethnic/multiracial cohort of patients with systemic lupus…”
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TCF-1-Centered Transcriptional Network Drives an Effector versus Exhausted CD8 T Cell-Fate Decision by Chen, Zeyu, Ji, Zhicheng, Ngiow, Shin Foong, Manne, Sasikanth, Cai, Zhangying, Huang, Alexander C., Johnson, John, Staupe, Ryan P., Bengsch, Bertram, Xu, Caiyue, Yu, Sixiang, Kurachi, Makoto, Herati, Ramin S., Vella, Laura A., Baxter, Amy E., Wu, Jennifer E., Khan, Omar, Beltra, Jean-Christophe, Giles, Josephine R., Stelekati, Erietta, McLane, Laura M., Lau, Chi Wai, Yang, Xiaolu, Berger, Shelley L., Vahedi, Golnaz, Ji, Hongkai, Wherry, E. John

“…TCF-1 is a key transcription factor in progenitor exhausted CD8 T cells (Tex). Moreover, this Tex cell subset mediates responses to PD-1 checkpoint pathway…”
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Rapid induction of antigen-specific CD4+ T cells is associated with coordinated humoral and cellular immunity to SARS-CoV-2 mRNA vaccination by Painter, Mark M., Mathew, Divij, Goel, Rishi R., Apostolidis, Sokratis A., Pattekar, Ajinkya, Kuthuru, Oliva, Baxter, Amy E., Herati, Ramin S., Oldridge, Derek A., Gouma, Sigrid, Hicks, Philip, Dysinger, Sarah, Lundgreen, Kendall A., Kuri-Cervantes, Leticia, Adamski, Sharon, Hicks, Amanda, Korte, Scott, Giles, Josephine R., Weirick, Madison E., McAllister, Christopher M., Dougherty, Jeanette, Long, Sherea, D’Andrea, Kurt, Hamilton, Jacob T., Betts, Michael R., Bates, Paul, Hensley, Scott E., Grifoni, Alba, Weiskopf, Daniela, Sette, Alessandro, Greenplate, Allison R., Wherry, E. John

“…SARS-CoV-2 mRNA vaccines have shown remarkable clinical efficacy, but questions remain about the nature and kinetics of T cell priming. We performed…”
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T-cell invigoration to tumour burden ratio associated with anti-PD-1 response by Huang, Alexander C., Postow, Michael A., Orlowski, Robert J., Mick, Rosemarie, Bengsch, Bertram, Manne, Sasikanth, Xu, Wei, Harmon, Shannon, Giles, Josephine R., Wenz, Brandon, Adamow, Matthew, Kuk, Deborah, Panageas, Katherine S., Carrera, Cristina, Wong, Phillip, Quagliarello, Felix, Wubbenhorst, Bradley, D’Andrea, Kurt, Pauken, Kristen E., Herati, Ramin S., Staupe, Ryan P., Schenkel, Jason M., McGettigan, Suzanne, Kothari, Shawn, George, Sangeeth M., Vonderheide, Robert H., Amaravadi, Ravi K., Karakousis, Giorgos C., Schuchter, Lynn M., Xu, Xiaowei, Nathanson, Katherine L., Wolchok, Jedd D., Gangadhar, Tara C., Wherry, E. John

“…Despite the success of monotherapies based on blockade of programmed cell death 1 (PD-1) in human melanoma, most patients do not experience durable clinical…”
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A single dose of neoadjuvant PD-1 blockade predicts clinical outcomes in resectable melanoma by Huang, Alexander C., Orlowski, Robert J., Xu, Xiaowei, Mick, Rosemarie, George, Sangeeth M., Yan, Patrick K., Manne, Sasikanth, Kraya, Adam A., Wubbenhorst, Bradley, Dorfman, Liza, D’Andrea, Kurt, Wenz, Brandon M., Liu, Shujing, Chilukuri, Lakshmi, Kozlov, Andrew, Carberry, Mary, Giles, Lydia, Kier, Melanie W., Quagliarello, Felix, McGettigan, Suzanne, Kreider, Kristin, Annamalai, Lakshmanan, Zhao, Qing, Mogg, Robin, Xu, Wei, Blumenschein, Wendy M., Yearley, Jennifer H., Linette, Gerald P., Amaravadi, Ravi K., Schuchter, Lynn M., Herati, Ramin S., Bengsch, Bertram, Nathanson, Katherine L., Farwell, Michael D., Karakousis, Giorgos C., Wherry, E. John, Mitchell, Tara C.

“…Immunologic responses to anti-PD-1 therapy in melanoma patients occur rapidly with pharmacodynamic T cell responses detectable in blood by 3 weeks. It is…”
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Convalescent-Phase Sera and Vaccine-Elicited Antibodies Largely Maintain Neutralizing Titer against Global SARS-CoV-2 Variant Spikes by Tada, Takuya, Dcosta, Belinda M, Samanovic, Marie I, Herati, Ramin S, Cornelius, Amber, Zhou, Hao, Vaill, Ada, Kazmierski, Wes, Mulligan, Mark J, Landau, Nathaniel R

“…The increasing prevalence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants with spike protein mutations raises concerns that antibodies…”
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CD4+ T Cell Differentiation in Chronic Viral Infections: The Tfh Perspective by Vella, Laura A., Herati, Ramin S., Wherry, E. John

“…CD4+ T cells play a critical role in the response to chronic viral infections during the acute phase and in the partial containment of infections once chronic…”
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A Feasibility Study of Implementing the Policies on Increasing Birth Rate with an Emphasis on Socio-economic Status: A Case Study of Kermanshah Metropolis, Western Iran by Reshadat, Sohyla, Zangeneh, Alireza, Saeidi, Shahram, Izadi, Neda, Ghasemi, S. Ramin, Rajabi-Gilan, Nader

“…Population and development have a mutual relationship, and more to the point, lack of sufficient knowledge on population development and fertility can lead to…”
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Abdominal pain in the ED: a 35 year retrospective by Hastings, Ramin S., MD, Powers, Robert D., MD

“…Abstract Objective Research published in 1972 and 1993 has detailed the demographics, diagnoses, and diagnostic test utilization of adult patients presenting…”
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A Comparison of Finite Element-Based Inversion Algorithms, Local Frequency Estimation, and Direct Inversion Approach Used in MRE by Honarvar, Mohammad, Sahebjavaher, Ramin S., Rohling, Robert, Salcudean, Septimiu E.

“…In quantitative elastography, maps of the mechanical properties of soft tissue, or elastograms, are calculated from the measured displacement data by solving…”
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Neutralization of SARS-CoV-2 Variants by mRNA and Adenoviral Vector Vaccine-Elicited Antibodies by Tada, Takuya, Zhou, Hao, Samanovic, Marie I, Dcosta, Belinda M, Cornelius, Amber, Herati, Ramin S, Mulligan, Mark J, Landau, Nathaniel R

“…The increasing prevalence of SARS-CoV-2 variants has raised concerns regarding possible decreases in vaccine effectiveness. Here, neutralizing antibody titers…”
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Multimodal single-cell datasets characterize antigen-specific CD8+ T cells across SARS-CoV-2 vaccination and infection by Zhang, Bingjie, Upadhyay, Rabi, Hao, Yuhan, Samanovic, Marie I., Herati, Ramin S., Blair, John D., Axelrad, Jordan, Mulligan, Mark J., Littman, Dan R., Satija, Rahul

“…The immune response to SARS-CoV-2 antigen after infection or vaccination is defined by the durable production of antibodies and T cells. Population-based…”
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Improving oligo-conjugated antibody signal in multimodal single-cell analysis by Buus, Terkild B, Herrera, Alberto, Ivanova, Ellie, Mimitou, Eleni, Cheng, Anthony, Herati, Ramin S, Papagiannakopoulos, Thales, Smibert, Peter, Odum, Niels, Koralov, Sergei B

“…Simultaneous measurement of surface proteins and gene expression within single cells using oligo-conjugated antibodies offers high-resolution snapshots of…”
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Increased resistance of SARS-CoV-2 Omicron variant to neutralization by vaccine-elicited and therapeutic antibodies by Tada, Takuya, Zhou, Hao, Dcosta, Belinda M, Samanovic, Marie I, Chivukula, Vidya, Herati, Ramin S, Hubbard, Stevan R, Mulligan, Mark J, Landau, Nathaniel R

“…SARS-CoV-2 vaccines currently authorized for emergency use have been highly successful in preventing infection and lessening disease severity. The vaccines…”
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Spatial distribution and function of T follicular regulatory cells in human lymph nodes by Sayin, Ismail, Radtke, Andrea J, Vella, Laura A, Jin, Wenjie, Wherry, E John, Buggert, Marcus, Betts, Michael R, Herati, Ramin S, Germain, Ronald N, Canaday, David H

“…T follicular regulatory (Tfr) cells are a population of CD4 T cells that express regulatory T cell markers and have been shown to suppress humoral immunity…”
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T follicular helper cells in human efferent lymph retain lymphoid characteristics by Vella, Laura A, Buggert, Marcus, Manne, Sasikanth, Herati, Ramin S, Sayin, Ismail, Kuri-Cervantes, Leticia, Bukh Brody, Irene, O'Boyle, Kaitlin C, Kaprielian, Hagop, Giles, Josephine R, Nguyen, Son, Muselman, Alexander, Antel, Jack P, Bar-Or, Amit, Johnson, Matthew E, Canaday, David H, Naji, Ali, Ganusov, Vitaly V, Laufer, Terri M, Wells, Andrew D, Dori, Yoav, Itkin, Maxim G, Betts, Michael R, Wherry, E John

“…T follicular helper cells (Tfh), a subset of CD4+ T cells, provide requisite help to B cells in the germinal centers (GC) of lymphoid tissue. GC Tfh are…”
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High-titer neutralization of Mu and C.1.2 SARS-CoV-2 variants by vaccine-elicited antibodies of previously infected individuals by Tada, Takuya, Zhou, Hao, Dcosta, Belinda M., Samanovic, Marie I., Cornelius, Amber, Herati, Ramin S., Mulligan, Mark J., Landau, Nathaniel R.

“…Recently identified severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants Mu and C.1.2 have spike proteins with mutations that may confer…”
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Transperineal prostate MR elastography: Initial in vivo results by Sahebjavaher, Ramin S., Baghani, Ali, Honarvar, Mohammad, Sinkus, Ralph, Salcudean, Septimiu E.

“…This article presents a new approach to magnetic resonance elastography of the prostate using transperineal mechanical excitation. This approach is validated…”
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Volumetric Analysis of the Prefrontal Cortex, Amygdala, and Hippocampus in Major Depression by HASTINGS, Ramin S, PARSEY, Ramin V, OQUENDO, Maria A, ARANGO, Victoria, MANN, J. John

“…Magnetic resonance imaging (MRI) studies in depressed subjects report smaller volumes of amygdala, hippocampus, inferior anterior cingulate, and the orbital…”
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