Search Results - "Ramesha, C S"

Cytoplasmic phospholipase A2 activity and gene expression are stimulated by tumor necrosis factor: dexamethasone blocks the induced synthesis by HOECK, W. G, RAMESHA, C. S, CHANG, D. J, FAN, N, HELLER, R. A

“…The interaction of tumor necrosis factor alpha (TNF) with its two membrane-bound receptors initiates intracellular events in which arachidonic acid and its…”
Get full text

TNF induces c‐fos via a novel pathway requiring conversion of arachidonic acid to a lipoxygenase metabolite by Haliday, E. M, Ramesha, C. S, Ringold, G

“…Tumour necrosis factor (TNF), a lymphokine released by activated macrophages, has diverse effects on a wide variety of cell types. TNF exerts these effects via…”
Get full text

Platelet-activating factor and leukotriene biosynthesis is inhibited in polymorphonuclear leukocytes depleted of arachidonic acid by Ramesha, C S, Pickett, W C

“…Rat peripheral or elicited polymorphonuclear leukocytes 90% deficient in arachidonic acid incorporate, after stimulation with the calcium ionophore A23187, 86%…”
Get full text

Resistance to killing by tumor necrosis factor in an adipocyte cell line caused by a defect in arachidonic acid biosynthesis by REID, T, RAMESHA, C. S, RINGOLD, G. M

“…We have found that TA1-R6, which are resistant to the cytotoxic effects of tumor necrosis factor (TNF) in the presence of cycloheximide (Reid, T. R., Torti,…”
Get full text

Fatty acid composition of diacyl, alkylacyl, and alkenylacyl phospholipids of control and arachidonate-depleted rat polymorphonuclear leukocytes by Ramesha, C S, Pickett, W C

“…Phospholipid fatty acid composition and phospholipid subclass distribution of control and arachidonate-depleted rat polymorphonuclear leukocytes (PMN) were…”
Get full text

The mechanism of membrane response to chilling. Effect of temperature on phospholipid deacylation and reacylation reactions in the cell surface membrane by Ramesha, C S, Thompson, G A

“…The ciliary membrane of Tetrahymena pyriformis is physically and metabolically remote from the main centers of lipid metabolism. Nevertheless, it possesses an…”
Get full text

On the formation of alpha-hydroxy fatty acids. Evidence for a direct hydroxylation of nonhydroxy fatty acid-containing sphingolipids by Kaya, K, Ramesha, C S, Thompson, G A

“…When Tetrahymena pyriformis, strain NT-1, was warmed from a growth temperature of 15 degrees C to 39 degrees C, there was a rapid conversion of its…”
Get full text

Metabolism of platelet-activating factor by arachidonic acid-depleted rat polymorphonuclear leukocytes by Ramesha, C S, Pickett, W C

“…1-O-[3H]Alkyl-2-acetyl-sn-glycero-3-phosphocholine ([3H]PAF) and 1-O-[3H]alkyl-2-lyso-sn-glycero-3-phosphocholine ([3H]lyso-PAF) when incubated with rat…”
Get full text

Species-specific variations in the molecular heterogeneity of the platelet-activating factor by Ramesha, CS, Pickett, WC

“…The molecular heterogeneity of platelet-activating factor (PAF) synthesized by unstimulated and Ca2+ ionophore (A23187)-stimulated PMN from rat, mouse, and…”
Get full text

Differential Allosteric Regulation of Prostaglandin H Synthase 1 and 2 by Arachidonic Acid by Swinney, D C, Mak, A Y, Barnett, J, Ramesha, C S

“…Prostaglandins are synthesized by prostaglandin H synthase (PGHS) 1 and 2. PGHS2 is regulated through inducible expression. We report here the regulation of…”
Get full text

Measurement of arachidonic acid release from human polymorphonuclear neutrophils and platelets: comparison between gas chromatographic and radiometric assays by Ramesha, C S, Taylor, L A

“…a simple gas chromatographic method for the assay of phospholipase A2 (PLA2) has been described in which arachidonic acid released from endogenous phospholipid…”
Get more information

Characterization of the analgesic and anti-inflammatory activities of ketorolac and its enantiomers in the rat by Jett, M F, Ramesha, C S, Brown, C D, Chiu, S, Emmett, C, Voronin, T, Sun, T, O'Yang, C, Hunter, J C, Eglen, R M, Johnson, R M

“…The marked analgesic efficacy of ketorolac in humans, relative to other nonsteroidal anti-inflammatory drugs (NSAIDs), has lead to speculation as to whether…”
Get more information

Changes in the lipid composition and physical properties of Tetrahymena ciliary membranes following low-temperature acclimation by Ramesha, C. S, Thompson, Guy A

“…This report describes the composition and physical properties of ciliary membranes isolated from Tetrahymena pyriformis grown at 39 and 15 degree C. These…”
Get full text

Temperature-induced changes in the hydroxy and non-hydroxy fatty acid-containing sphingolipids abundant in the surface membrane of Tetrahymena pyriformis NT-1 by Kaya, K, Ramesha, C S, Thompson, Jr, G A

“…Sphingolipids make up 30 to 40 mole % of the phospholipids found in the surface membrane of Tetrahymena pyriformis NT-1. We have identified the two major…”
Get full text

Metabolic products of arachidonic acid in rats by Ramesha, C S, Gronke, R S, Sivarajan, M, Lands, W E

“…The pattern of eicosanoid metabolites appearing in urine and feces following oral administration of radioactive arachidonic acid was investigated using rats…”
Get more information

Human neutrophil platelet-activating factor: molecular heterogeneity in unstimulated and ionophore-stimulated cells by Ramesha, C S, Pickett, W C

“…The molecular heterogeneity of platelet-activating factor (PAF) in resting and ionophore (A23187) -stimulated human neutrophils was measured by a very…”
Get more information

Human and rat cyclooxygenases are pharmacologically distinct by Ramesha, C S

Get more information

Effect of dietary unsaturated oils on the biosynthesis of cholesterol, and on biliary and fecal excretion of cholesterol and bile acids in rats by Ramesha, C S, Paul, R, Ganguly, J

“…The aim of the present work was to investigate whether the hypocholesterolemic effect of polyunsaturated oils is due to inhibition of cholesterol synthesis or…”
Get more information

Quantification of phospholipid molecular species by coupled gas chromatography-mass spectrometry of deuterated samples by Dickens, B F, Ramesha, C S, Thompson, Jr, G A

Get more information

Phospholipid molecular species alterations in Tetrahymena ciliary membranes following low-temperature acclimation by Ramesha, C S, Dickens, B F, Thompson, Jr, G A

“…The molecular species compositions of phosphatidylcholine, phosphatidylethanolamine, and 2-(aminoethyl)-phosphonolipid, the three principal phosphoglycerides…”
Get full text