Search Results - "Ramesh, Thevendran"

Gold-Hybridized Zinc Oxide Nanorods as Real-Time Low-Cost NanoBiosensors for Detection of virulent DNA signature of HPV-16 in Cervical Carcinoma by Ramesh, Thevendran, Foo, Kai Loong, R., Haarindraprasad, Sam, Annie Jeyachristy, Solayappan, Maheswaran

“…Detection of host integrated viral oncogenes are critical for early and point-of-care molecular diagnostics of virus-induced carcinoma. However, available…”
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The Diagnostic Potential of RNA Aptamers against the NS1 Protein of Dengue Virus Serotype 2 by Thevendran, Ramesh, Rogini, Sivalingam, Leighton, Glenn, Mutombwera, Atherton, Shigdar, Sarah, Tang, Thean-Hock, Citartan, Marimuthu

“…Dengue infection, caused by the dengue virus, is a global threat which requires immediate attention and appropriate disease management. The current diagnosis…”
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Reverse Electrochemical Sensing of FLT3-ITD Mutations in Acute Myeloid Leukemia Using Gold Sputtered ZnO-Nanorod Configured DNA Biosensors by Thevendran, Ramesh, Foo, Kai Loong, Hussin, Mohd Hazwan, Moses, Emmanuel Jairaj, Citartan, Marimuthu, Prasad, Haarindraprasad Rajintra, Maheswaran, Solayappan

“…Detection of genetic mutations leading to hematological malignancies is a key factor in the early diagnosis of acute myeloid leukemia (AML). FLT3-ITD mutations…”
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Assays to Estimate the Binding Affinity of Aptamers by Thevendran, Ramesh, Citartan, Marimuthu

“…Aptamers have become coming-of-age molecular recognition elements in both diagnostic and therapeutic applications. Generated by SELEX, the ‘quality control’ of…”
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Recognizing CRISPR as the new age disease‐modifying drug: Strategies to bioengineer CRISPR/Cas for direct in vivo delivery by Thevendran, Ramesh, Maheswaran, Solayappan

“…Clustered regularly interspaced short palindromic repeats (CRISPR) have established itself as a frontier technology in genetic engineering. Researchers have…”
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In silico molecular docking in DNA aptamer development by Navien, Tholasi Nadhan, Thevendran, Ramesh, Hamdani, Hazrina Yusof, Tang, Thean-Hock, Citartan, Marimuthu

“…Aptamers are single-stranded DNA or RNA oligonucleotides generated by SELEX that exhibit binding affinity and specificity against a wide variety of target…”
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Prospects of Innovative Therapeutics in Combating the COVID-19 Pandemic by Mahendran, Thamby Rajah, Cynthia, Binsin, Thevendran, Ramesh, Maheswaran, Solayappan

“…The sudden global crisis of COVID-19, driven by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), demands swift containment measures due to its…”
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Strategies to bioengineer aptamer-driven nanovehicles as exceptional molecular tools for targeted therapeutics: A review by Thevendran, Ramesh, Sarah, Shigdar, Tang, Thean-Hock, Citartan, Marimuthu

“…Aptamers are a class of folded nucleic acid strands capable of binding to different target molecules with high affinity and selectivity. Over the years, they…”
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In‐silico selection employing rigid docking and molecular dynamic simulation in selecting DNA aptamers against androgen receptor by Thevendran, Ramesh, Tang, Thean‐Hock, Citartan, Marimuthu

“…Aptamers are a class of single‐stranded (ss) nucleic acid molecules generated through Systematic Evolution of Ligands by Exponential Enrichment (SELEX) that…”
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Spiked nanorosette: A novel zinc oxide‐gold textured nanostructure for impedance biosensing of target DNA signatures by Haarindraprasad, Rajintra Prasad, Thurga Devi, Nathan, Thevendran, Ramesh, Maheswaran, Solayappan

“…The creation of nanostructure is profound for the generation of nanobiosensors in several medical diagnosis. Here, we employed an aqueous hydrothermal route…”
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Mathematical approaches in estimating aptamer-target binding affinity by Thevendran, Ramesh, Navien, Tholasi Nadhan, Meng, Xin, Wen, Kechun, Lin, Qiao, Sarah, Shigdar, Tang, Thean-Hock, Citartan, Marimuthu

“…The performance of aptamers as versatile tools in numerous analytical applications is critically dependent on their high target binding specificity and…”
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