Search Results - "Ramesh, Prathyaya"
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Increased Otoferlin Expression in B Cells Is Associated with Muscle Weakness in Untreated Juvenile Dermatomyositis: A Pilot Study
Published in International journal of molecular sciences (23-06-2023)“…Otoferlin mRNA expression is increased in JDM patients' PBMCs and muscle compared to healthy controls. This study aims to evaluate the role of otoferlin in JDM…”
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HSP70iQ435A to subdue autoimmunity and support anti-tumor responses
Published in Cell stress & chaperones (01-09-2021)“…Developing immunosuppressive therapies for autoimmune diseases comes with a caveat that immunosuppression may promote the risk of developing other conditions…”
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Skin Infiltrate Composition as a Telling Measure of Responses to Checkpoint Inhibitors
Published in JID innovations (01-09-2023)“…Checkpoint inhibitors treat a variety of tumor types with significant benefits. Unfortunately, these therapies come with diverse adverse events. Skin rash is…”
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Benign tumors in TSC are amenable to treatment by GD3 CAR T cells in mice
Published in JCI insight (22-11-2021)“…Mutations underlying disease in tuberous sclerosis complex (TSC) give rise to tumors with biallelic mutations in TSC1 or TSC2 and hyperactive mammalian target…”
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A Palette of Cytokines to Measure Anti-Tumor Efficacy of T Cell-Based Therapeutics
Published in Cancers (16-02-2021)“…Cytokines are key molecules within the tumor microenvironment (TME) that can be used as biomarkers to predict the magnitude of anti-tumor immune responses…”
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Loss of SWI/SNF Complex Subunit Arid1a in B Cells Promotes Inflammation and Perturbs Germinal Center B Cell Responses
Published in Blood (02-11-2023)“…The Switch/Sucrose Non-Fermentable (SWI/SNF) complex is a major mediator of nucleosomal remodeling in eukaryotic genomes and plays a crucial role in the…”
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Arid1a-dependent canonical BAF complex suppresses inflammatory programs to drive efficient germinal center B cell responses
Published in Nature immunology (01-09-2024)“…The mammalian Brg1/Brm-associated factor (BAF) complexes are major regulators of nucleosomal remodeling that are commonly mutated in several cancers, including…”
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HSP70i Q435A to subdue autoimmunity and support anti-tumor responses
Published in Cell stress & chaperones (01-09-2021)“…Developing immunosuppressive therapies for autoimmune diseases comes with a caveat that immunosuppression may promote the risk of developing other conditions…”
Get full text
Journal Article