Search Results - "Ramesh, Bala"

Investigating the performance of a novel pH and cathepsin B sensitive, stimulus-responsive nanoparticle for optimised sonodynamic therapy in prostate cancer by Hadi, Marym Mohammad, Nesbitt, Heather, Masood, Hamzah, Sciscione, Fabiola, Patel, Shiv, Ramesh, Bala S., Emberton, Mark, Callan, John F., MacRobert, Alexander, McHale, Anthony P., Nomikou, Nikolitsa

“…Nano-formulations that are responsive to tumour-related and externally-applied stimuli can offer improved, site-specific antitumor effects, and can improve the…”
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Cellular glycosylation affects Herceptin binding and sensitivity of breast cancer cells to doxorubicin and growth factors by Peiris, Diluka, Spector, Alexander F., Lomax-Browne, Hannah, Azimi, Tayebeh, Ramesh, Bala, Loizidou, Marilena, Welch, Hazel, Dwek, Miriam V.

“…Alterations in protein glycosylation are a key feature of oncogenesis and have been shown to affect cancer cell behaviour perturbing cell adhesion, favouring…”
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Increased Adipose Tissue Expression of Hepcidin in Severe Obesity Is Independent From Diabetes and NASH by Bekri, Soumeya, Gual, Philippe, Anty, Rodolphe, Luciani, Nathalie, Dahman, Monsef, Ramesh, Bala, Iannelli, Antonio, Staccini–Myx, Aline, Casanova, Dominique, Ben Amor, Imed, Saint–Paul, Marie–Christine, Huet, Pierre–Michel, Sadoul, Jean–Louis, Gugenheim, Jean, Srai, Surjit Kaila S., Tran, Albert, Le Marchand–Brustel, Yannick

“…Backgrounds & Aims: Hepcidin is an acute-phase response peptide. We have investigated the possible involvement of hepcidin in massive obesity, a state of…”
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Divalent metal-dependent regulation of hepcidin expression by MTF-1 by Balesaria, Sara, Ramesh, Bala, McArdle, Harry, Bayele, Henry K., Srai, Surjit K.S.

“…Hepcidin is a small acute phase peptide that regulates iron absorption. It is induced by inflammation and infection, but is repressed by anaemia and hypoxia…”
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Efficacy of the specific endothelin a receptor antagonist zibotentan (ZD4054) in colorectal cancer: a preclinical study by Haque, Samer-ul, Dashwood, Michael R, Heetun, Mohammed, Shiwen, Xu, Farooqui, Noreen, Ramesh, Bala, Welch, Hazel, Savage, Felicity J, Ogunbiyi, Olagunju, Abraham, David J, Loizidou, Marilena

“…Endothelin 1 (ET-1) is overexpressed in cancer, contributing to disease progression. We previously showed that ET-1 stimulated proliferative, migratory, and…”
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Fluorescence-Guided Laparoscopic Surgery: What If We Could Label Pancreatic Cancer with Biomarker-Conjugated Fluorescent Quantum Nanocrystals? by Giorgakis, Emmanouil, MD, MSc, Loizidou, Marilena, PhD, Mavroeidis, Vasileios, MD, Imber, Charles, MD, Ramesh, Bala, PhD

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Effect of hepcidin on intestinal iron absorption in mice by Laftah, Abas H., Ramesh, Bala, Simpson, Robert J., Solanky, Nita, Bahram, Seiamak, Schümann, Klaus, Debnam, Edward S., Srai, Surjit K.S.

“…The effect of the putative iron regulatory peptide hepcidin on iron absorption was investigated in mice. Hepcidin peptide was synthesized and injected into…”
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Interaction between soluble and membrane-embedded potassium channel peptides monitored by Fourier transform infrared spectroscopy by Abbott, Geoffrey W, Ramesh, Bala, Srai, Surjit K

“…Recent studies have explored the utility of Fourier transform infrared spectroscopy (FTIR) in dynamic monitoring of soluble protein-protein interactions. Here,…”
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A novel POSS-coated quantum dot for biological application by Rizvi, Sarwat B, Yildirimer, Lara, Ghaderi, Shirin, Ramesh, Bala, Seifalian, Alexander M, Keshtgar, Mo

“…Quantum dots (QDs) are fluorescent semiconductor nanocrystals that have the potential for major advancements in the field of nanomedicine through their unique…”
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Ghrelin Can Bind to a Species of High Density Lipoprotein Associated with Paraoxonase by Beaumont, Nicholas J, Skinner, Vernon O, Tan, Tricia M-M, Ramesh, Bala S, Byrne, Dominic J, MacColl, Gavin S, Keen, Jeff N, Bouloux, Pierre M, Mikhailidis, Dimitri P, Bruckdorfer, K Richard, Vanderpump, Mark P, Srai, Kaila S

“…Ghrelin is a 28-residue peptide hormone that is principally released from the stomach during fasting and prior to eating. Two forms are present in human…”
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Nramp2 Expression Is Associated with pH-dependent Iron Uptake across the Apical Membrane of Human Intestinal Caco-2 Cells by Tandy, Sarah, Williams, Mark, Leggett, Aime, Lopez-Jimenez, Marta, Dedes, Markos, Ramesh, Bala, Srai, Surjit Kaila, Sharp, Paul

“…The absorption of dietary non-heme iron by intestinal enterocytes is crucial to the maintenance of body iron homeostasis. This process must be tightly…”
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Effects of zinc on factor I cofactor activity of C4b-binding protein and factor H by Blom, Anna M, Kask, Lena, Ramesh, Bala, Hillarp, Andreas

“…Complement inhibition is to a large extent achieved by proteolytic degradation of activated complement factors C3b and C4b by factor I (FI). This reaction…”
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Fluorescence nanoparticles "quantum dots" as drug delivery system and their toxicity: a review by Ghaderi, Shirin, Ramesh, Bala, Seifalian, Alexander M.

“…Fluorescence nanocrystals or quantum dots (QDs) are engineered nanoparticles (NP) that have shown great promise with potential for many biological and…”
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Mechano-growth Factor Expression in Colorectal Cancer Investigated With Fluorescent Gold Nanoparticles by Alagaratnam, Swethan, Yang, Shi-Yu, Loizidou, Marilena, Fuller, Barry, Ramesh, Bala

“…Fluorescent gold nanoparticles demonstrate strong photoluminescence, photostability, and low cellular toxicity, making them attractive agents for biomedical…”
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Increased expression of IGF-1Ec with increasing colonic polyp dysplasia and colorectal cancer by Alagaratnam, Swethan, Loizidou, Marilena, Yang, Shi- yu, Fuller, Barry, Ramesh, Bala

“…Purpose IGF-1Ec is an isoform of Insulin-like growth factor 1 (IGF-1) and has recently been identified to be overexpressed in cancers including prostate and…”
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The anti-calcification potential of a silsesquioxane nanocomposite polymer under in vitro conditions: Potential material for synthetic leaflet heart valve by Ghanbari, Hossein, Kidane, Asmeret G., Burriesci, Gaetano, Ramesh, Bala, Darbyshire, Arnold, Seifalian, Alexander M.

“…Calcification currently represents a major cause of failure of biological tissue heart valves. It is a complex phenomenon influenced by a number of biochemical…”
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Demonstration of Calreticulin Expression in Hamster Pancreatic Adenocarcinoma with the Use of Fluorescent Gold Quantum Dots by Giorgakis, Emmanouil, Ramesh, Bala, Kamali-Dashtarzheneh, Ashkan, Fusai, Giuseppe Kito, Imber, Charles, Tsironis, Dimitrios, Loizidou, Marilena

“…There is dire need for discovery of novel pancreatic cancer biomarkers and of agents with the potential for simultaneous diagnostic and therapeutic capacity…”
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Synthesis of mercaptosuccinic acid/MercaptoPolyhedral oligomeric silsesquioxane coated cadmium telluride quantum dots in cell labeling applications by Ghaderi, Shirin, Ramesh, Bala, Seifalian, Alexander M

“…An aqueous synthesis method to obtain highly luminescent cadmium telluride nanocrystals is described. We have shown water-soluble semi-conductor quantum dots…”
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Ex vivo tracing of pancreatic neuroendocrine tumors with bio-conjugated fluorescent quantum dots: a paradigm of nanoparticle-based diagnostics by Giorgakis, Emmanouil, Ramesh, Bala, Loizidou, Marilena

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Efficacy of zibotentan in colorectal cancer--response by Haque, Samer-Ul, Welch, Hazel, Dashwood, Michael, Ramesh, Bala, Loizidou, Marilena

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