Search Results - "Ramello, María C"

CD39 Expression Defines Cell Exhaustion in Tumor-Infiltrating CD8 + T Cells by Canale, Fernando P, Ramello, María C, Núñez, Nicolás, Araujo Furlan, Cintia L, Bossio, Sabrina N, Gorosito Serrán, Melisa, Tosello Boari, Jimena, Del Castillo, Andrés, Ledesma, Marta, Sedlik, Christine, Piaggio, Eliane, Gruppi, Adriana, Acosta Rodríguez, Eva A, Montes, Carolina L

“…The ability of CD8 T lymphocytes to eliminate tumors is limited by their ability to engender an immunosuppressive microenvironment. Here we describe a subset…”
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CAR-T Engineering: Optimizing Signal Transduction and Effector Mechanisms by Roselli, Emiliano, Frieling, Jeremy S., Thorner, Konrad, Ramello, María C., Lynch, Conor C., Abate-Daga, Daniel

“…The adoptive transfer of genetically engineered T cells expressing a chimeric antigen receptor (CAR) has shown remarkable results against B cell malignancies…”
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CD39+ conventional CD4+ T cells with exhaustion traits and cytotoxic potential infiltrate tumors and expand upon CTLA-4 blockade by Bossio, Sabrina N., Abrate, Carolina, Tosello Boari, Jimena, Rodriguez, Constanza, Canale, Fernando P., Ramello, María C., Brunotto, Valentina, Richer, Wilfrid, Rocha, Dario, Sedlik, Christine, Vincent-Salomon, Anne, Borcoman, Edith, Del Castillo, Andres, Gruppi, Adriana, Fernandez, Elmer, Acosta Rodríguez, Eva V., Piaggio, Eliane, Montes, Carolina L.

“…Conventional CD4 + T (Tconv) lymphocytes play important roles in tumor immunity; however, their contribution to tumor elimination remains poorly understood…”
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IL-17RA-Signaling Modulates CD8+ T Cell Survival and Exhaustion During Trypanosoma cruzi Infection by Tosello Boari, Jimena, Araujo Furlan, Cintia L, Fiocca Vernengo, Facundo, Rodriguez, Constanza, Ramello, María C, Amezcua Vesely, María C, Gorosito Serrán, Melisa, Nuñez, Nicolás G, Richer, Wilfrid, Piaggio, Eliane, Montes, Carolina L, Gruppi, Adriana, Acosta Rodríguez, Eva V

“…The IL-17 family contributes to host defense against many intracellular pathogens by mechanisms that are not fully understood. CD8+ T lymphocytes are key…”
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Unconventional Pro-inflammatory CD4 + T Cell Response in B Cell-Deficient Mice Infected with Trypanosoma cruzi by Gorosito Serrán, Melisa, Tosello Boari, Jimena, Fiocca Vernengo, Facundo, Beccaría, Cristian G, Ramello, María C, Bermejo, Daniela A, Cook, Amelia G, Vinuesa, Carola G, Montes, Carolina L, Acosta Rodriguez, Eva V, Gruppi, Adriana

“…Chagas disease, caused by the parasite , is endemic in Latin America but has become a global public health concern by migration of infected people. It has been…”
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An immunoproteomic approach to characterize the CAR interactome and signalosome by Ramello, Maria C, Benzaïd, Ismahène, Kuenzi, Brent M, Lienlaf-Moreno, Maritza, Kandell, Wendy M, Santiago, Daniel N, Pabón-Saldaña, Mibel, Darville, Lancia, Fang, Bin, Rix, Uwe, Yoder, Sean, Berglund, Anders, Koomen, John M, Haura, Eric B, Abate-Daga, Daniel

“…Adoptive transfer of T cells that express a chimeric antigen receptor (CAR) is an approved immunotherapy that may be curative for some hematological cancers…”
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PD-L1 + Regulatory B Cells Are Significantly Decreased in Rheumatoid Arthritis Patients and Increase After Successful Treatment by Zacca, Estefanía R, Onofrio, Luisina I, Acosta, Cristina D V, Ferrero, Paola V, Alonso, Sergio M, Ramello, María C, Mussano, Eduardo, Onetti, Laura, Cadile, Isaac I, Stancich, Maria I, Taboada Bonfanti, Maria C, Montes, Carolina L, Acosta Rodríguez, Eva V, Gruppi, Adriana

“…B cells play an important role in the development and maintenance of rheumatoid arthritis (RA). Although IL-10-producing B cells represent a major subset of…”
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CD39 Expression Defines Cell Exhaustion in Tumor-Infiltrating CD8 + T Cells-Response by Canale, Fernando P, Ramello, María C, Núñez, Nicolás, Bossio, Sabrina N, Piaggio, Eliane, Gruppi, Adriana, Rodríguez, Eva V Acosta, Montes, Carolina L

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Polyfunctional KLRG-1 + CD57 + Senescent CD4 + T Cells Infiltrate Tumors and Are Expanded in Peripheral Blood From Breast Cancer Patients by Ramello, Maria C, Núñez, Nicolás G, Tosello Boari, Jimena, Bossio, Sabrina N, Canale, Fernando P, Abrate, Carolina, Ponce, Nicolas, Del Castillo, Andrés, Ledesma, Marta, Viel, Sophie, Richer, Wilfrid, Sedlik, Christine, Tiraboschi, Carolina, Muñoz, Marcos, Compagno, Daniel, Gruppi, Adriana, Acosta Rodríguez, Eva V, Piaggio, Eliane, Montes, Carolina L

“…Senescent T cells have been described during aging, chronic infections, and cancer; however, a comprehensive study of the phenotype, function, and…”
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CAR-T cells and combination therapies: What’s next in the immunotherapy revolution? by Ramello, Maria C., Haura, Eric B., Abate-Daga, Daniel

“…[Display omitted] Cancer immunotherapies are dramatically reshaping the clinical management of oncologic patients. For many of these therapies, the guidelines…”
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Enhanced T cell effector activity by targeting the Mediator kinase module by Freitas, Katherine A, Belk, Julia A, Sotillo, Elena, Quinn, Patrick J, Ramello, Maria C, Malipatlolla, Meena, Daniel, Bence, Sandor, Katalin, Klysz, Dorota, Bjelajac, Jeremy, Xu, Peng, Burdsall, Kylie A, Tieu, Victor, Duong, Vandon T, Donovan, Micah G, Weber, Evan W, Chang, Howard Y, Majzner, Robbie G, Espinosa, Joaquin M, Satpathy, Ansuman T, Mackall, Crystal L

“…T cells are the major arm of the immune system responsible for controlling and regressing cancers. To identify genes limiting T cell function, we conducted…”
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The biology and therapeutic management of melanoma brain metastases by Abate-Daga, Daniel, Ramello, Maria C., Smalley, Inna, Forsyth, Peter A., Smalley, Keiran S.M.

“…[Display omitted] The recent years have seen significant progress in the development of systemic therapies to treat patients with advanced melanoma. Use of…”
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Inhibitory Receptor Expression on T Cells as a Marker of Disease Activity and Target to Regulate Effector Cellular Responses in Rheumatoid Arthritis by Onofrio, Luisina I., Zacca, Estefania R., Ferrero, Paola, Acosta, Cristina, Mussano, Eduardo, Onetti, Laura, Cadile, Isaac, Gazzoni, M. Victoria, Jurado, Raúl, Boari, Jimena Tosello, Ramello, Maria C., Montes, Carolina L., Gruppi, Adriana, Acosta Rodríguez, Eva V.

“…Objective Inhibitory receptors are essential for the regulation of effector immune responses and may play critical roles in autoimmune diseases. We evaluated…”
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Abstract 2815: Exploring the role of telomerase in senescence and exhaustion in CAR T cell immunotherapy by Murty, Tara, Ramello, Maria C., Sotillo, Elena, Chen, Lu, Artandi, Steven A., Mackall, Crystal L.

“…Abstract Chimeric antigen receptor (CAR) T cell therapy has revolutionized oncology through engineered targeting of antigens on previously untreatable cancers…”
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