Heroin addictions in Italians: Evaluation of OPRM1 genetic variants by case–control association study

Heroin addictions in Italians: Evaluation of OPRM1 genetic variants by case–control association study

The opportunities to analyse the genetic variations related to the risk of addiction are of interest to forensics, who beside their involvement in drugs-related fatalities may also be required to assess driving and working ability as well as permanent invalidity due to drugs-related conditions. Seve...

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Bibliographic Details
Published in:Forensic science international. Genetics supplement series Vol. 4; no. 1; pp. e57 - e58
Main Authors: Buscemi, L., Turchi, C., Onori, N., Ramberti, F., Tagliabracci, A.
Format: Journal Article
Language:English
Published: Elsevier Ireland Ltd 2013
Subjects:
Association study
Drug addiction
Heroin
OPRM1 gene
SNPs
SNPs
Association study
Drug addiction
OPRM1 gene
Heroin
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Summary:The opportunities to analyse the genetic variations related to the risk of addiction are of interest to forensics, who beside their involvement in drugs-related fatalities may also be required to assess driving and working ability as well as permanent invalidity due to drugs-related conditions. Several genetic variants have been shown to be associated with heroin addiction. The most investigated gene is OPMR1 that encode the μ-opioid receptor. The purpose of this study was to examine the contribution of genetics variants in OPRM1 to the susceptibility to addiction.
ISSN:1875-1768
1875-175X
DOI:10.1016/j.fsigss.2013.10.029