Search Results - "Rambert, Francis"
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Effect of the wake-promoting agent Modafinil on sleep-promoting neurons from the ventrolateral preoptic nucleus: an in vitro pharmacologic study
Published in Sleep (New York, N.Y.) (01-02-2004)“…The pharmacologic profile of modafinil, an increasingly popular wake-promoting drug for narcolepsy treatment, differs from those of classic psychostimulants…”
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Differential enhancement of dialysate serotonin levels in distinct brain regions of the awake rat by modafinil: Possible relevance for wakefulness and depression
Published in Journal of neuroscience research (01-04-2002)“…The present in vivo microdialysis study evaluates the possible existence of a differential regulation of serotonergic transmission by the antinarcoleptic drug…”
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The vigilance promoting drug modafinil increases dopamine release in the rat nucleus accumbens via the involvement of a local GABAergic mechanism
Published in European journal of pharmacology (13-06-1996)“…The present in vivo microdialysis study demonstrated that the subcutaneous injection of modafinil (diphenyl-methyl-sulfinyl-2-acetamide) in doses of 30–300…”
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Modafinil does not affect serotonin efflux from rat frontal cortex synaptosomes: comparison with known serotonergic drugs
Published in Brain research (16-03-2001)“…Modafinil did not affect spontaneous and K +-evoked [ 3H]5-HT efflux from cortical synaptosomes while it increased K +-evoked tritium efflux from cortical…”
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Modafinil prevents glutamate cytotoxicity in cultured cortical neurons
Published in Neuroreport (21-12-1998)“…THE ability of modafinil (Modiodal®) to protect cortical neurons from glutamate-induced degeneration was evaluated by measuring electrically evoked [H]GABA…”
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The vigilance promoting drug modafinil increases extracellular glutamate levels in the medial preoptic area and the posterior hypothalamus of the conscious rat:: Prevention by local GABA A receptor blockade
Published in Neuropsychopharmacology (New York, N.Y.) (01-04-1999)Get full text
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Modafinil: An antinarcoleptic drug with a different neurochemical profile to d-amphetamine and dopamine uptake blockers
Published in Biological psychiatry (1969) (15-12-1997)Get full text
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The effects of modafinil on striatal, pallidal and nigral GABA and glutamate release in the conscious rat: evidence for a preferential inhibition of striato-pallidal GABA transmission
Published in Neuroscience letters (04-09-1998)“…The effects of the anti-narcoleptic drug modafinil (30–300 mg/kg i.p.) on GABA and glutamate release were evaluated in the basal ganglia of the conscious rat,…”
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The antinarcoleptic drug modafinil increases glutamate release in thalamic areas and hippocampus
Published in Neuroreport (08-09-1997)“…THE antinarcoleptic drug modafinil [(diphenyl-methyl)sulfinyl-2-acetamide; Modiodal] dose-dependently inhibits the activity of GABA neurons in the cerebral…”
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The vigilance promoting drug modafinil decreases GABA release in the medial preoptic area and in the posterior hypothalamus of the awake rat : possible involvement of the serotonergic 5-HT3 receptor
Published in Neuroscience letters (06-12-1996)“…The effect of modafinil on endogenous gamma-aminobutyric acid (GABA) release in the medial preoptic area (MPA) and posterior hypothalamus (PH) and the role of…”
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Modafinil and cortical γ-aminobutyric acid outflow. Modulation by 5-hydroxytryptamine neurotoxins
Published in European journal of pharmacology (1995)“…The acute or chronic administration of modafinil, (diphenyl-methyl-sulfinyl-2-acetamide, 30 mg/kg s.c.) decreased γ-aminobutyric acid (GABA) outflow from the…”
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Effects of the vigilance promoting drug modafinil on the synthesis of GABA and glutamate in slices of rat hypothalamus
Published in Neuroscience letters (1999)“…The effects of the vigilance promoting drug modafil were studied ex vivo (100 mg/kg; i.p.) and in vitro (10–1000 μM modafinil) on the synthesis of [ 3H]…”
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Awakening properties of modafinil : effect on nocturnal activity in monkeys (Macaca mulatta) after acute and repeated administration
Published in Psychopharmacologia (1991)“…Single oral administration of modafinil (16-64 mg/kg) in monkeys induced an increase in nocturnal activity and in behavioural arousal without stereotyped…”
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The vigilance promoting drug modafinil decreases GABA release in the medial preoptic area and in the posterior hypothalamus of the awake rat: possible involvement of the serotonergic 5-HT 3 receptor
Published in Neuroscience letters (1996)“…The effect of modafinil on endogenous γ-aminobutyric acid (GABA) release in the medial preoptic area (MPA) and posterior hypothalamus (PH) and the role of…”
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The Vigilance Promoting Drug Modafinil Increases Extracellular Glutamate Levels in the Medial Preoptic Area and the Posterior Hypothalamus of the Conscious Rat: Prevention by Local GABAA Receptor Blockade
Published in Neuropsychopharmacology (New York, N.Y.) (01-04-1999)“…The effects of modafinil on glutamatergic and GABAergic transmission in the rat medial preoptic area (MPA) and posterior hypothalamus (PH), are analysed…”
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