Search Results - "Ramazeilles, C."

A randomized phase II study of alternating and sequential regimens of docetaxel and doxorubicin as first-line chemotherapy for metastatic breast cancer by Paridaens, R., Van Aelst, F., Georgoulias, V., Samonnig, H., Cocquyt, V., Zielinski, C., Hausmaninger, H., Willemse, P., Boudraa, Y., Wildiers, J., Ramazeilles, C., Azli, N.

“…Background: This phase II study evaluated the feasibility and efficacy of alternating and sequential regimens of docetaxel and doxorubicin as first-line…”
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Phase II Study of Sequential Administration of Docetaxel Followed by Doxorubicin and Cyclophosphamide as First-Line Chemotherapy in Metastatic Breast Cancer by KHAYAT, D, CHOLLET, P, RAMAZEILLES, C, AZLI, N, ANTOINE, E. C, MONFARDINI, S, AMBROSINI, G, BENHAMMOUDA, A, MAZEN, M.-F, SORIO, R, BORG-OLIVIER, O, RIVA, A

“…To evaluate the feasibility and efficacy of a sequential administration of four cycles of docetaxel (100 mg/m(2) every 3 weeks) followed by four cycles of…”
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Phase I study of docetaxel in combination with cyclophosphamide as first-line chemotherapy for metastatic breast cancer by VASEY, P. A, ROCHE, H, BISSET, D, TERRET, C, VERNILLET, L, RIVA, A, RAMAZEILLES, C, AZLI, N, KAYE, S. B, TWELVES, C. J

“…This phase I was study conducted to establish the maximum tolerated dose, dose-limiting toxicity, and recommended dose of docetaxel in combination with…”
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Antisense Phosphorothioate Oligonucleotides: Selective Killing of the Intracellular Parasite Leishmania amazonensis by Ramazeilles, Claude, Mishra, Rakesh K., Moreau, Serge, Pascolo, Emanuelle, Toulmé, Jean-Jacques

“…We targeted the mini-exon sequence, present at the 5' end of every mRNA of the protozoan parasite Leishmania amazonensis, by phosphorothioate oligonucleotides…”
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Destruction of Leishmania mexicana amazonensis amastigotes within macrophages by lysosomotropic amino acid esters by RABINOVITCH, M, ZILBERFARB, V, RAMAZEILLES, C

“…Leishmania amastigotes parasitize almost exclusively the mononuclear phagocytes of mammals. The organisms survive and multiply within acidified vacuoles…”
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A phase I dose escalation safety and pharmacokinetic (PK) study of SSR244738 administered as a one-hour intravenous (IV) infusion twice-weekly during a 3-week cycle in patients (pts) with refractory solid tumors by Isambert, N., Spitaleri, G., Fumoleau, P., Noberasco, C., Ramazeilles, C., Chadjaa, M., Bolloni, L., De Braud, F.

“…Abstract only 2539 Background: SSR244738 is a new cytotoxic agent (G2-cell cycle inhibitor). In this first in man study the original schedule of administration…”
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The anti-leishmanial activity of dipeptide esters on Leishmania amazonensis amastigotes by Ramazeilles, C, Juliano, L, Chagas, J R, Rabinovitch, M

“…L-Amino acid esters, such as L-Leu-OMe, kill Leishmania amazonensis amastigotes by a mechanism which appears to involve ester hydrolysis by cysteine…”
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A phase I dose escalation safety and pharmacokinetic (PK) study of SSR244738 administered as a one-hour intravenous (IV) infusion every 3 weeks in patients (pt) with refractory solid tumors by De Braud, F. G., Isambert, N., Curigliano, G., Spitaleri, G., Ferrant, E., Ramazeilles, C., Bolloni, L., Fumoleau, P.

“…Abstract only 2518 Background: This phase I study of SSR244738, a G2-cell cycle inhibitor cytotoxic agent, was aimed to establish the dose limiting toxicities…”
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Leishmanicidal activity of amino acid and peptide esters: an update by Rabinovitch, M, Alfieri, S C, Ramazeilles, C, Quintao, L G, Antoine, J C, Ryter, A, Zilberfarb, V, Shaw, E, Juliano, L

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156 Lenograstim associated or not to ARA-C (3mg/m2X2) as therapy for poor prognosis refractory anemia with excess of blasts (RAEB) by Chomienne, C., Chevret, S., Fenaux, P., Guerci, A., Bordessoule, D., Solary, E., Stoppa, AM, Leporrier, M., Dreyfus, F., Varet, B., Brière, J., Rochant, H., Blot, I., de Revel, T., Baumelou, E., Maloisel, F., Najman, A., Travade, P., Ramazeilles, C., Schuller, M.P.

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Leishmania amazonensis: uptake and hydrolysis of 3H-amino acid methyl esters by isolated amastigotes by Ramazeilles, C, Rabinovitch, M

“…Intracellular and isolated amastigotes of Leishmania amazonensis can be destroyed by L-amino acid methyl esters known to disrupt mammalian lysosomes. To…”
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Improved leishmanicidal effect of phosphorotioate antisense oligonucleotides by LDL-mediated delivery by Mishra, R K, Moreau, C, Ramazeilles, C, Moreau, S, Bonnet, J, Toulmé, J J

“…We have designed antisense oligonucleotides that can interact with lipoproteins in order to use them as vectors to facilitate the uptake by those cells…”
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Leishmania amazonensis: specific labeling of amastigote cysteine proteinases by radioiodinated N-benzyloxycarbonyl-tyrosyl-alanyl diazomethane by Alfieri, S C, Pral, E M, Shaw, E, Ramazeilles, C, Rabinovitch, M

“…Living Leishmania amazonensis amastigotes were incubated with radioiodinated N-benzyloxycarbonyl-L-tyrosyl-L-alanyl diazomethane (Z-Tyr-AlaCHN2), an…”
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Proteinase inhibitors protect Leishmania amazonensis amastigotes from destruction by amino acid esters by Alfieri, S C, Ramazeilles, C, Zilberfarb, V, Galpin, I, Norman, S E, Rabinovitch, M

“…Lysosomotropic amino acid esters and amides kill Leishmania amazonensis amastigotes by a mechanism which probably involves enzymatic hydrolysis of the…”
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Leishmanicidal activity of amino acid and peptide esters: an update by Rabinovitch, M., Alfieri, S. C., Ramazeilles, C., Quintão, L. G., Antoine, J. C., Ryter, A., Zilberfarb, V., Shaw, E., Juliano, L.

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