Search Results - "Ramaswamy, Kalyanasundaram"
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Development and Evaluation of a Fluorescent Antibody-Drug Conjugate for Molecular Imaging and Targeted Therapy of Pancreatic Cancer
Published in PloS one (23-06-2016)“…Antibodies are widely available and cost-effective research tools in life science, and antibody conjugates are now extensively used for targeted therapy,…”
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Wuchereria bancrofti macrophage migration inhibitory factor‐2 (rWbaMIF‐2) ameliorates experimental colitis
Published in Parasite immunology (01-04-2020)“…Immunomodulatory molecules produced by helminth parasites are receiving much attention recently as novel therapeutic agents for inflammation and autoimmune…”
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3
Identification and characterization of a novel nematode pan allergen (NPA) from Wuchereria bancrofti and their potential role in human filarial tropical pulmonary eosinophilia (TPE)
Published in PLoS neglected tropical diseases (01-02-2024)“…Tropical pulmonary eosinophilia (TPE) is a chronic respiratory syndrome associated with Lymphatic Filariasis (LF), a tropical parasitic infection of the human,…”
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Evaluating the Vaccine Potential of a Tetravalent Fusion Protein ( rBm HAXT) Vaccine Antigen Against Lymphatic Filariasis in a Mouse Model
Published in Frontiers in immunology (02-07-2018)“…Lymphatic filariasis (LF) is a tropical parasitic infection of human transmitted by mosquitoes. Chronic infection results in severe physical disability in the…”
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Parasite Cystatin: Immunomodulatory Molecule with Therapeutic Activity against Immune Mediated Disorders
Published in Pathogens (Basel) (30-05-2020)“…The use of parasites or their products for treating chronic inflammation associated diseases (CIADs) has generated significant attention recently. Findings…”
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Piperine, a Bioactive Component of Pepper Spice Exerts Therapeutic Effects on Androgen Dependent and Androgen Independent Prostate Cancer Cells
Published in PloS one (18-06-2013)“…Prostate cancer is the most common solid malignancy in men, with 32,000 deaths annually. Piperine, a major alkaloid constituent of black pepper, has previously…”
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Cystatin from Filarial Parasites Suppress the Clinical Symptoms and Pathology of Experimentally Induced Colitis in Mice by Inducing T-Regulatory Cells, B1-Cells, and Alternatively Activated Macrophages
Published in Biomedicines (31-10-2019)“…Potential alternative therapeutic strategies for immune-mediated disorders are being increasingly recognized and are studied extensively. We previously…”
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Improving the efficacy of a prophylactic vaccine formulation against lymphatic filariasis
Published in Parasitology research (1987) (01-10-2017)“…Mass drug administration (MDA) is the current strategy for interrupting the transmission of lymphatic filariasis (LF) infection and control of the disease in…”
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Large extracellular loop of tetraspanin as a potential vaccine candidate for filariasis
Published in PloS one (11-10-2013)“…Lymphatic filariasis affects nearly 120 million people worldwide and mass preventive chemotherapy is currently used as a strategy to control this infection…”
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Epidemiological screening and xenomonitoring for human lymphatic filariasis infection in select districts in the states of Maharashtra and Karnataka, India
Published in Parasitology research (1987) (01-03-2019)“…Lymphatic filariasis (LF) is a mosquito-transmitted tropical neglected parasitic infection that currently affects over 120 million people around the world and…”
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Evaluation of a multivalent vaccine against lymphatic filariasis in rhesus macaque model
Published in PloS one (17-11-2014)“…Lymphatic filariasis affects 120 million people worldwide and another 1.2 billion people are at risk of acquiring the infection. Chemotherapy with mass drug…”
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Alteration of rhesus macaque serum N-glycome during infection with the human parasitic filarial nematode Brugia malayi
Published in Scientific reports (21-09-2022)“…Serum N-glycan profiling studies during the past decades have shown robust associations between N-glycan changes and various biological conditions, including…”
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Biochemical characterization and evaluation of a Brugia malayi small heat shock protein as a vaccine against lymphatic filariasis
Published in PloS one (05-04-2012)“…Filarial nematodes enjoy one of the longest life spans of any human pathogen due to effective immune evasion strategies developed by the parasite. Among the…”
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Evaluation of Wuchereria bancrofti GST as a vaccine candidate for lymphatic filariasis
Published in PLoS neglected tropical diseases (09-06-2009)“…Lymphatic filarial parasites survive within the lymphatic vessels for years despite the complex immune environment surrounding them. Parasites possibly…”
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Sumoylation of Human Translationally Controlled Tumor Protein Is Important for Its Nuclear Transport
Published in Biochemistry Research International (01-01-2012)“…Translationally controlled tumor protein (TCTP) lacks nuclear bipartite localization signal sequence; yet TCTP is present abundantly in the nucleus. At present…”
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Praziquantel Affects the Regulatory Myosin Light Chain of Schistosoma mansoni
Published in Antimicrobial Agents and Chemotherapy (01-03-2009)“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Translationally controlled tumor protein of Brugia malayi functions as an antioxidant protein
Published in Parasitology research (1987) (01-11-2007)“…Translationally controlled tumor protein (TCTP) is one of the most abundantly expressed proteins in the filarial parasites as well as in the other organisms…”
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Sero-diagnostic evaluation of Toxoplasma gondii recombinant Rhoptry antigen 8 expressed in E. coli
Published in Parasites & vectors (01-07-2014)“…BACKGROUND: Toxoplasma gondii infects all warm-blooded animals, including humans. Early diagnosis and determining the infective stage are critical for…”
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Therapeutic implications of inflammasome in inflammatory bowel disease
Published in The FASEB journal (01-05-2021)“…Inflammatory bowel disease (IBD) remains a persistent health problem with a global burden surging over 6.8 million cases currently. Clinical pathology of IBD…”
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Human Dendritic Cell-Specific Intercellular Adhesion Molecule-Grabbing Nonintegrin (CD209) Is a Receptor for Yersinia pestis That Promotes Phagocytosis by Dendritic Cells
Published in Infection and Immunity (01-05-2008)“…Yersinia pestis is the etiologic agent of bubonic and pneumonic plagues. It is speculated that Y. pestis hijacks antigen-presenting cells (APCs), such as…”
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