Search Results - "Ramasamy, Ramalakshmi"

Histone Acetylome-wide Association Study of Autism Spectrum Disorder by Sun, Wenjie, Poschmann, Jeremie, Cruz-Herrera del Rosario, Ricardo, Parikshak, Neelroop N., Hajan, Hajira Shreen, Kumar, Vibhor, Ramasamy, Ramalakshmi, Belgard, T. Grant, Elanggovan, Bavani, Wong, Chloe Chung Yi, Mill, Jonathan, Geschwind, Daniel H., Prabhakar, Shyam

“…The association of histone modification changes with autism spectrum disorder (ASD) has not been systematically examined. We conducted a histone acetylome-wide…”
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Animal modeling of lower urinary tract dysfunction associated with multiple sclerosis: Part I: Justification of the mouse model for MS research by Ramasamy, Ramalakshmi, Smith, Phillip P.

“…Lower urinary tract symptoms and dysfunction (LUTS/LUTD) contribute to loss of quality of life, morbidity, and need for medical intervention in most patients…”
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PART 2: Mouse models for multiple sclerosis research by Ramasamy, Ramalakshmi, Smith, Phillip P.

“…Lower urinary tract symptoms and dysfunction (LUTS/LUTD) contribute to loss of quality of life, morbidity, and need for medical intervention in most patients…”
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ELDERLY MOUSE DETRUSOR MAINTAINS ITS PEAK FORCE OF CONTRACTION OVER TIME by Mortman, Nadav, Ramasamy, Ramalakshmi, Smith, Phillip

“…Abstract Aging is a risk factor for urinary dysfunction. Detrusor weakening has been thought to contribute to the old bladder phenotype. Animal detrusor strips…”
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STABILIZING ROLE OF HCN CHANNELS ON POST-CAMP MECHANISMS OF DETRUSOR MYOCYTE CONTROL by Ramasamy, Ramalakshmi, AlObaidi, Alya, Smith, Phillip

“…Abstract Aging is associated with an increased incidence of co-morbidities, including detrusor underactivity (DU). DU is defined as the failure to create…”
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Cuprizone‐mediated demyelination reversibly degrades voiding behavior in mice while sparing brainstem reflex by Ramasamy, Ramalakshmi, Hardy, Cara C., Crocker, Stephen J., Smith, Phillip P.

“…Multiple sclerosis (MS) is a chronic, progressively debilitating demyelinating disease of the central nervous system (CNS). Nearly 80% of MS patients…”
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The hyperpolarization-activated, cyclic nucleotide-gated channel resides on myocytes in mouse bladders and contributes to adrenergic-induced detrusor relaxation by Lemtiri-Chlieh, Fouad, Baker, Dylan S, Al-Naggar, Iman M, Ramasamy, Ramalakshmi, Kuchel, George A, Levine, Eric S, Robson, Paul, Smith, Phillip P

“…Control of urinary continence is predicated on sensory signaling about bladder volume. Bladder sensory nerve activity is dependent on tension, implicating…”
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Remyelination Improves Voiding Dysfunction in a Mouse Model of Multiple Sclerosis by Ramasamy, Ramalakshmi, Hardy, Cara, Crocker, Stephen, Smith, Phillip

“…Abstract Multiple sclerosis (MS) is a chronic inflammatory demyelinating disease of the central nervous system (CNS). Of note, over 80% of MS patients have…”
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SenNet recommendations for detecting senescent cells in different tissues by Suryadevara, Vidyani, Hudgins, Adam D, Rajesh, Adarsh, Pappalardo, Alberto, Karpova, Alla, Dey, Amit K, Hertzel, Ann, Agudelo, Anthony, Rocha, Azucena, Soygur, Bikem, Schilling, Birgit, Carver, Chase M, Aguayo-Mazzucato, Cristina, Baker, Darren J, Bernlohr, David A, Jurk, Diana, Mangarova, Dilyana B, Quardokus, Ellen M, Enninga, Elizabeth Ann L, Schmidt, Elizabeth L, Chen, Feng, Duncan, Francesca E, Cambuli, Francesco, Kaur, Gagandeep, Kuchel, George A, Lee, Gung, Daldrup-Link, Heike E, Martini, Helene, Phatnani, Hemali, Al-Naggar, Iman M, Rahman, Irfan, Nie, Jia, Passos, João F, Silverstein, Jonathan C, Campisi, Judith, Wang, Julia, Iwasaki, Kanako, Barbosa, Karina, Metis, Kay, Nernekli, Kerem, Niedernhofer, Laura J, Ding, Li, Wang, Lichao, Adams, Lisa C, Ruiyang, Liu, Doolittle, Madison L, Teneche, Marcos G, Schafer, Marissa J, Xu, Ming, Hajipour, Mohammadjavad, Boroumand, Mozhgan, Basisty, Nathan, Sloan, Nicholas, Slavov, Nikolai, Kuksenko, Olena, Robson, Paul, Gomez, Paul T, Vasilikos, Periklis, Adams, Peter D, Carapeto, Priscila, Zhu, Quan, Ramasamy, Ramalakshmi, Perez-Lorenzo, Rolando, Fan, Rong, Dong, Runze, Montgomery, Ruth R, Shaikh, Sadiya, Vickovic, Sanja, Yin, Shanshan, Kang, Shoukai, Suvakov, Sonja, Khosla, Sundeep, Garovic, Vesna D, Menon, Vilas, Xu, Yanxin, Song, Yizhe, Suh, Yousin, Dou, Zhixun, Neretti, Nicola

“…Once considered a tissue culture-specific phenomenon, cellular senescence has now been linked to various biological processes with both beneficial and…”
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Alzheimer's disease amyloidogenesis is linked to altered lower urinary tract physiology by Hardy, Cara C., Ramasamy, Ramalakshmi, Rosenberg, Dawn A., Kuchel, George A., Yan, Riqiang, Hu, Xiangyou, Smith, Phillip P.

“…Aims While most Alzheimer's disease (AD) research emphasizes cognitive and behavioral abnormalities, lower urinary tract symptoms (LUTS) are observed in a…”
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Alzheimer’s Disease-Associated Pathology in a Transgenic Mouse Model Results in Altered Voiding Function by Hardy, Cara, Rosenberg, Dawn, Ramasamy, Ramalakshmi, Hu, Xiangyou, Smith, Phillip

“…Abstract Alzheimer’s disease (AD) is a devastating disorder primarily affecting older adults and is the most common neurodegenerative disease in the US. More…”
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Detrusor Underactivity as an HCN-Mediated Failure of Resilience in Aging by Rosenberg, Dawn, Hardy, Cara, Ramasamy, Ramalakshmi, Smith, Phillip

“…Abstract Sympathetic relaxation of the bladder wall permits low pressure urine storage and allows central regulation of afferent sensitivity to volume…”
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Effects of CNS Demyelination and Myelin Recovery on Urinary Physiology by Ramasamy, Ramalakshmi, Rosenberg, Dawn, Hardy, Cara, Crocker, Stephen, Smith, Phillip

“…Abstract Multiple sclerosis (MS) is a chronic inflammatory demyelinating disease of the central nervous system (CNS). Of note, over 80% of MS patients have…”
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Loss of Awareness or Urinary Dysfunction? Investigating Amyloidosis and Urinary Physiology in a Transgenic Mouse by Hardy, Cara, Ramasamy, Ramalakshmi, Rosenberg, Dawn, Scarpa, Philip, Hu, Xiangyou, Kuchel, George, Smith, Phillip

“…Abstract Alzheimer’s disease (AD) is a devastating disorder primarily affecting older adults and is the most common neurodegenerative disease in the US. More…”
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Loss of resilience contributes to detrusor underactivity in advanced age by Ramasamy, Ramalakshmi, Baker, Dylan S., Lemtiri-Chlieh, Fouad, Rosenberg, Dawn A., Woon, Eric, Al-Naggar, Iman M., Hardy, Cara C., Levine, Eric S., Kuchel, George A., Bartley, Jenna M., Smith, Phillip P.

“…Volume hyposensitivity resulting from impaired sympathetic detrusor relaxation during bladder filling contributes to detrusor underactivity (DU) associated…”
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OMAP-8: Multiplexed Antibody-Based Imaging of Placenta with Imaging Mass Cytometry (IMC), v1.0 by Ramasamy, Ramalakshmi

“…OMAP-8 was designed for Imaging Mass Cytometry (IMC) (https://pubmed.ncbi.nlm.nih.gov/24584193/) of formalin-fixed paraffin-embedded (FFPE) human term-placenta…”
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