Search Results - "Ramaraju, Harsha"
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Innovative design of minimal invasive biodegradable poly(glycerol-dodecanoate) nucleus pulposus scaffold with function regeneration
Published in Nature communications (30-06-2023)“…Minimally invasive biodegradable implants with regeneration have been a frontier trend in clinic. Degeneration of nucleus pulposus (NP) is irreversible in most…”
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Degradation properties of a biodegradable shape memory elastomer, poly(glycerol dodecanoate), for soft tissue repair
Published in PloS one (21-02-2020)“…Development of biodegradable shape memory elastomers (SMEs) is driven by the growing need for materials to address soft tissue pathology using a minimally…”
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Cell and Material‐Specific Phage Display Peptides Increase iPS‐MSC Mediated Bone and Vasculature Formation In Vivo
Published in Advanced healthcare materials (01-05-2019)“…Biomimetically designed materials matching the chemical and mechanical properties of tissue support higher mesenchymal stem cell (MSC) adhesion. However,…”
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Manufacture Dependent Differential Biodegradation of 3D Printed Shape Memory Polymers
Published in Virtual and physical prototyping (31-12-2024)“…In the field of tissue engineering, 3D printed shape memory polymers (SMPs) are drawing increased interest. Understanding how these 3D printed SMPs degrade is…”
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Evaluating Directional Dependency of Selective Laser Sintered Patient Specific Biodegradable Devices to Improve Predictive Modeling and Design Verification
Published in Annals of biomedical engineering (01-09-2021)“…Additive manufacturing, or 3D printing, of the bioresorbable polymer ε -polycaprolactone (PCL) is an emerging tissue engineering solution addressing patient…”
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Ceramides and other bioactive sphingolipid backbones in health and disease: Lipidomic analysis, metabolism and roles in membrane structure, dynamics, signaling and autophagy
Published in Biochimica et biophysica acta (01-12-2006)“…Sphingolipids are comprised of a backbone sphingoid base that may be phosphorylated, acylated, glycosylated, bridged to various headgroups through…”
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Selective Binding of pVTK Peptide- and Bisphosphonate-Functionalized Micelles to Prostate Cancer Cells, Osteoblasts, and Osteoclasts
Published in Precision nanomedicine (02-03-2022)“…<img src=” https://s3.amazonaws.com/production.scholastica/article/35438/large/prnano_722021_ga.jpg?1651243768”> This report describes the development of…”
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Novel Synthesis and Biological Evaluation of Enigmols as Therapeutic Agents for Treating Prostate Cancer
Published in ACS medicinal chemistry letters (09-06-2011)“…Enigmol is a synthetic, orally active 1-deoxysphingoid base analogue that has demonstrated promising activity against prostate cancer. In these studies, the…”
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Development of Photocrosslinked Poly(glycerol dodecanedioate)—A Biodegradable Shape Memory Polymer for 3D‐Printed Tissue Engineering Applications
Published in Advanced engineering materials (01-10-2021)“…Surgical procedures increasingly use minimally invasive techniques, which often use shape memory materials for device deployment. Poly(glycerol‐dodecanedioate)…”
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Designing Biodegradable Shape Memory Polymers for Tissue Repair
Published in Advanced functional materials (01-10-2020)“…Shape memory materials, specifically nickel–titanium alloys, are used in a number of minimally invasive clinical procedures demonstrating significant…”
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Biodegradation Behavior Control for Shape Memory Polyester Poly(Glycerol-Dodecanoate): An In Vivo and In Vitro Study
Published in Biomacromolecules (12-06-2023)“…Poly(glycerol-dodecanoate) (PGD) has garnered increasing attention in biomedical engineering for its degradability, shape memory, and rubber-like mechanical…”
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Multimodal 3D printing of biodegradable shape memory elastomer resins for patient specific soft tissue repair
Published in Applied materials today (01-12-2022)“…•First publication of VP 3D printing of biodegradable shape memory elastomer APGD.•Significant differences between APGD samples due to VP versus ME 3D…”
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Dual-functioning peptides discovered by phage display increase the magnitude and specificity of BMSC attachment to mineralized biomaterials
Published in Biomaterials (01-07-2017)“…Abstract Design of biomaterials for cell-based therapies requires presentation of specific physical and chemical cues to cells, analogous to cues provided by…”
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Clinical grade manufacture of 3D printed patient specific biodegradable devices for pediatric airway support
Published in Biomaterials (01-10-2022)“…Implantable patient-specific devices are the next frontier of personalized medicine, positioned to improve the quality of care across multiple clinical…”
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Percutaneous delivery and degradation of a shape memory elastomer poly(glycerol dodecanedioate) in porcine pulmonary arteries
Published in Biomaterials (01-02-2023)“…Shape memory biodegradable elastomers are an emergent class of biomaterials well-suited for percutaneous cardiovascular repair requiring nonlinear elastic…”
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Degradation properties of a biodegradable shape memory elastomer, poly
Published in PloS one (21-02-2020)“…Development of biodegradable shape memory elastomers (SMEs) is driven by the growing need for materials to address soft tissue pathology using a minimally…”
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Shape memory cycle conditions impact human bone marrow stromal cell binding to RGD- and YIGSR-conjugated poly (glycerol dodecanedioate)
Published in Acta biomaterialia (15-09-2024)“…Bioresorbable shape memory polymers (SMP) are an emerging class of polymers that can help address several challenges associated with minimally invasive surgery…”
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Finite element analysis of esophageal atresia repair with biodegradable polymer sleeves
Published in Journal of the mechanical behavior of biomedical materials (01-09-2022)“…Esophageal atresia, which occurs in 1 in every 4100 live births, is a potentially lethal congenital malformation resulting in discontinuity of the esophagus…”
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Sterilization effects on poly(glycerol dodecanedioate): A biodegradable shape memory elastomer for biomedical applications
Published in Journal of biomedical materials research. Part B, Applied biomaterials (01-04-2023)“…Biodegradable shape memory polymers provide unique regenerative medicine approaches in minimally invasive surgeries. Once heated, thermally responsive shape…”
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Modulating nonlinear elastic behavior of biodegradable shape memory elastomer and small intestinal submucosa(SIS) composites for soft tissue repair
Published in Journal of the mechanical behavior of biomedical materials (01-10-2020)“…Structural repair of soft tissue for regenerative therapies can be advanced by developing biocompatible and bioresorbable materials with mechanical properties…”
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