Search Results - "Ramanitrahasimbola, David"
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Antioxidant, Anti-Inflammatory, and Antidiabetic Activities of Leaves and Stems of Uapaca bojeri Bail. (EUPHORBIACEAE), an Endemic Plant of Madagascar
Published in Pharmaceuticals (Basel, Switzerland) (17-04-2020)“…is an endemic Malagasy plant used by the local population. This work aimed to evaluate antioxidant, anti-inflammatory, and antidiabetic activities of the…”
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Assessing a "Least-Concern" Red List Tree Species from Madagascar Used in Traditional Medicine: Morella spathulata (Myricaceae) Phyto-Compounds and Anti-Inflammatory Properties
Published in Plants (Basel) (01-10-2024)“…(Myricaceae family) is a common plant from Madagascar and is present on the IUCN Red List of threatened species classified at the 'least concern' level, used…”
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3
Chemical composition, antimicrobial activity, and antioxidant capacity of Micromeria flagellaris Baker and M. madagascariensis Baker: Two endemic species from Madagascar as sources of essential oils
Published in Heliyon (15-03-2024)“…The aerial parts of Micromeria madagascariensis Baker and M. flagellaris Baker are used by the population of the Vakinankaratra and Itasy regions (Madagascar)…”
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Quali-Quantitative Fingerprinting of the Fruit Extract of Uapaca bojeri Bail. ( Euphorbiaceae ) and Its Antioxidant, Analgesic, Anti-Inflammatory, and Antihyperglycemic Effects: An Example of Biodiversity Conservation and Sustainable Use of Natural Resources in Madagascar
Published in Plants (Basel) (19-01-2023)“…Antioxidants are important supplements for the human body for their roles in human life for the maintenance of homeostasis. Tapia fruits ( ) are used by the…”
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Sickle cell disease: Ethnopharmacological survey in the eastern part of Madagascar
Published in South African journal of botany (01-11-2024)“…Sickle cell disease (SCD) is one of the most devastating inherited haemoglobinopathy that affects mostly children. Its prevalence can reach up to 13 % in the…”
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In silico ADMET and anti-inflammatory profiles of the stigmast-4-en-3-one and isolation of isovanillin as the antioxidant principle of Imperata cylindrica (L.) P. Beauv
Published in Natural product research (31-01-2024)“…(L.) P. Beauv. is an invasive species widely used in treatment of several diseases associated with pain and inflammation in different countries including…”
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Bio-guided isolation of androsta-1,4-dien-3,16-dione as a vasodilator active principle from the inflorescence of Ravenala madagascariensis Sonn. (Strelitziaceae)
Published in Natural product research (01-03-2023)“…Androsta-1,4-dien-3,16-dione was isolated for the first time from the plant kingdom of the ethanolic extract of the ' inflorescence by the bio-guided method…”
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Phytochemical and pharmacological activities of Schefflera bojeri (Seem.) R. Vig. (Araliaceae)
Published in South African journal of botany (01-12-2022)“…Schefflera bojeri possesses several therapeutic virtues: the leaves are used to alleviate hypertension and the bark for the treatment of diabetes. This work…”
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Self‐nanoemulsifying drug delivery system to improve transcorneal permeability of voriconazole: in‐vivo studies
Published in Journal of pharmacy and pharmacology (01-07-2020)“…Objective This study investigates the effectiveness of self‐nanoemulsifying drug delivery system (SNEDDS) in improving voriconazole transcorneal permeability…”
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10
Phytochemical and Pharmacological Profile of Four Malagasy Medicinal Plants Used in Different Chronic Diseases: Strategies for the Sustainable Use of Natural Resources in the Malagasy Health System
Published in Medical sciences forum (01-11-2022)“…Traditional medicine plays an important role in the Malagasy health system. In Madagascar, medicinal plants are the main remedies for several diseases,…”
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Development and validation of a selective and effective pressurized liquid extraction followed by liquid chromatography–mass spectrometry method for the determination of fructosazine analogues in the ammonia treated extract of Eugenia jambolana Lamarck seeds
Published in Journal of Chromatography A (18-11-2016)“…•A directly hyphenated HPLC-ESI–MS technique without use of a SPE purification.•Selective extraction and chromatographic separation of…”
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Quali–Quantitative Fingerprinting of the Fruit Extract of IUapaca bojeri/I Bail. and Its Antioxidant, Analgesic, Anti-Inflammatory, and Antihyperglycemic Effects: An Example of Biodiversity Conservation and Sustainable Use of Natural Resources in Madagascar
Published in Plants (Basel) (01-01-2023)“…Antioxidants are important supplements for the human body for their roles in human life for the maintenance of homeostasis. Tapia fruits (Uapaca bojeri) are…”
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13
Antiplasmodial phenolic compounds from Piptadenia pervillei
Published in Planta medica (01-03-2008)“…Piptadenia pervillei Vatke (Fabaceae) was selected from a screening programme devoted to the search of naturally-occuring antimalarial compounds from plants of…”
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Malagashanine potentiates chloroquine antimalarial activity in drug resistant Plasmodium malaria by modifying both its efflux and influx
Published in Molecular and biochemical parasitology (01-03-2006)“…Malagashanine (MG) is the parent compound of the new N b-C(21) seco-curan alkaloids isolated hitherto from Madagascan Strychnos. On account of its promising…”
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Exploiting a basic chemosensitizing pharmacophore hypothesis. Part 1: Synthesis and biological evaluation of novel arylbromide and bicyclic chemosensitizers against drug-resistant malaria parasites
Published in Bioorganic & medicinal chemistry letters (15-06-2005)“…A new series of chemosensitizers against drug resistant and sensitive strains of P. falciparum were designed on the basis of a basic chemosensitizing…”
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Flavonoids from Dalbergia louvelii and Their Antiplasmodial Activity
Published in Journal of natural products (Washington, D.C.) (01-11-2003)“…Four new flavonoids (1-4), along with 13 known compounds, were isolated from the heartwood of Dalbergia louvelii by following their potential to inhibit in…”
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Clerodane and labdane diterpenoids from Nuxia sphaerocephala
Published in Phytochemistry (Oxford) (01-03-2006)“…Four clerodane and three labdane diterpenoids ( 1– 7) were isolated from the leaves of Nuxia sphaerocephala. Their structures have been elucidated on the basis…”
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Screening extracts of Madagascan plants in search of antiplasmodial compounds
Published in Phytotherapy research (01-09-2004)“…One hundred and ninety plants, of which 51 are used to treat malaria in traditional medicine, were collected in five different ecosystems of Madagascar for a…”
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Synthesis and chloroquine-enhancing activity of N a-deacetyl-ferrocenoyl-strychnobrasiline
Published in Bioorganic & medicinal chemistry letters (15-02-2005)“…The synthesis (yield 22%) as well as the in vitro (IC 50 = 4.83 μg/mL) and in vivo antiplasmodial and chemosensitizing activities of N…”
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20
Synthesis and chloroquine-enhancing activity of Na-deacetyl-ferrocenoyl-strychnobrasiline
Published in Bioorganic & medicinal chemistry letters (15-02-2005)“…Several strychnobrasiline derivatives have been synthesized to overcome the lack of in vivo reversal activity of the parent compound. In the present study,…”
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