Search Results - "Ramanathan, Y"
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SCCRO (DCUN1D1) Promotes Nuclear Translocation and Assembly of the Neddylation E3 Complex
Published in The Journal of biological chemistry (25-03-2011)“…SCCRO/DCUN1D1/DCN1 (squamous cell carcinoma-related oncogene/defective in cullin neddylation 1 domain containing 1/defective in cullin neddylation) serves as…”
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Mouse DCUN1D1 (SCCRO) is required for spermatogenetic individualization
Published in PloS one (01-01-2019)“…Squamous cell carcinoma-related oncogene (SCCRO, also known as DCUN1D1) is a component of the E3 for neddylation. As such, DCUN1D1 regulates the neddylation of…”
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SCCRO (DCUN1D1) Is an Essential Component of the E3 Complex for Neddylation
Published in The Journal of biological chemistry (28-11-2008)“…Covalent modification of cullins by the ubiquitin-like protein NEDD8 (neddylation) regulates protein ubiquitination by promoting the assembly of cullin-RING…”
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Oncogenic Function of SCCRO5/DCUN1D5 Requires Its Neddylation E3 Activity and Nuclear Localization
Published in Clinical cancer research (15-01-2014)“…To determine mechanisms by which SCCRO5 (aka DCUN1D5) promotes oncogenesis. SCCRO5 mRNA and protein expression were assessed in 203 randomly selected primary…”
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Squamous Cell Carcinoma Related Oncogene/DCUN1D1 is highly conserved and activated by amplification in squamous cell carcinomas
Published in Cancer research (Chicago, Ill.) (01-10-2006)“…Chromosomal amplification at 3q is common to multiple human cancers, but has a specific predilection for squamous cell carcinomas (SCC) of mucosal origin. We…”
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SCCRO (DCUN1D1) Induces Extracellular Matrix Invasion by Activating Matrix Metalloproteinase 2
Published in Clinical cancer research (01-11-2008)“…Purpose: Ectopic expression of squamous cell carcinoma–related oncogene ( SCCRO or DCUN1D1 ) in NIH-3T3 cells induces invasion in vitro and produces highly…”
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Three RNA Polymerase II Carboxyl-terminal Domain Kinases Display Distinct Substrate Preferences
Published in The Journal of biological chemistry (06-04-2001)“…CDK7, CDK8, and CDK9 are cyclin-dependent kinases (CDKs) that phosphorylate the C-terminal domain (CTD) of RNA polymerase II. They have distinct functions in…”
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Overexpression of SCCRO2 in Hepatocellular Carcinoma Correlates With Increased Neddylation Activity
Published in The Journal of surgical research (2012)Get full text
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Human and Rodent Transcription Elongation Factor P-TEFb: Interactions with Human Immunodeficiency Virus Type 1 Tat and Carboxy-Terminal Domain Substrate
Published in Journal of Virology (01-07-1999)“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Squamous Cell Carcinoma-related Oncogene (SCCRO) Family Members Regulate Cell Growth and Proliferation through Their Cooperative and Antagonistic Effects on Cullin Neddylation
Published in The Journal of biological chemistry (18-03-2016)“…SCCRO (squamous cell carcinoma-related oncogene; also known as DCUN1D1) is a highly conserved gene that functions as an E3 in neddylation. Although…”
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SCCRO3 (DCUN1D3) Antagonizes the Neddylation and Oncogenic Activity of SCCRO (DCUN1D1)
Published in The Journal of biological chemistry (12-12-2014)“…The activity of cullin-RING type ubiquitination E3 ligases is regulated by neddylation, a process analogous to ubiquitination that culminates in covalent…”
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Functional cloning, sorting, and expression profiling of nucleic acid-binding proteins
Published in Genome research (01-08-2002)“…A major challenge in the post-sequencing era is to elucidate the activity and biological function of genes that reside in the human genome. An important subset…”
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Functional cloning of genes encoding dsRNA binding proteins
Published in Methods (San Diego, Calif.) (01-08-2003)“…Over a dozen human genes code for proteins that specifically bind to double-stranded RNA. These proteins have been implicated in several important cellular…”
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EZ‐Retrieve: a web‐server for batch retrieval of coordinate‐specified human DNA sequences and underscoring putative transcription factor‐binding sites
Published in Nucleic acids research (01-11-2002)“…The availability of a draft human genome sequence and ability to monitor the transcription of thousands of genes with DNA microarrays has necessitated the need…”
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Study of rain episode in the desert region of the Indian summer monsoon trough
Published in Atmospheric environment (1994) (1995)“…A rain episode over the desert region of the summer monsoon trough during the period 1–4 July 1990 is discussed in the study. The fine structure observations…”
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Mouse DCUN1D1
Published in PloS one (17-01-2019)“…Squamous cell carcinoma-related oncogene (SCCRO, also known as DCUN1D1) is a component of the E3 for neddylation. As such, DCUN1D1 regulates the neddylation of…”
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Journal Article -
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Transcription elongation factor P-TEFb is required for HIV-1 tat transactivation in vitro
Published in Genes & development (15-10-1997)“…P-TEFb is a key regulator of the process controlling the processivity of RNA polymerase II and possesses a kinase activity that can phosphorylate the…”
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Identification, mapping and characterization of two genes ofEscherichia coli K-12 regulating growth and resistance to streptomycin in cold
Published in Journal of genetics (01-04-1997)“…Escherichia coli MD1157, a routine isolate of AB1157 maintained in our laboratory, was noticed to have spontaneously acquired two conditional cold-dependent…”
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SCCRO/DCUN1D-gene family is commonly dysregulated in non-small cell lung cancers
Published in Journal of clinical oncology (20-05-2008)“…Abstract only…”
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