Search Results - "Ramanathan, Gnanasambandan"
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Kidney injury molecule-1; is it a predictive marker for renal diseases?
Published in Journal of nephropharmacology (01-06-2023)“…Kidney injury is the main cause of mortality and morbidity globally. The kidney injury molecule (KIM-1) is a type 1 transmembrane protein, which is been…”
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2
Role of Immune Cells and Receptors in Cancer Treatment: An Immunotherapeutic Approach
Published in Vaccines (Basel) (01-09-2022)“…Cancer immunotherapy moderates the immune system's ability to fight cancer. Due to its extreme complexity, scientists are working to put together all the…”
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The Implication of Mechanistic Approaches and the Role of the Microbiome in Polycystic Ovary Syndrome (PCOS): A Review
Published in Metabolites (14-01-2023)“…As a complex endocrine and metabolic condition, polycystic ovarian syndrome (PCOS) affects women's reproductive health. These common symptoms include…”
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4
Molecular Crosstalk between the Immunological Mechanism of the Tumor Microenvironment and Epithelial–Mesenchymal Transition in Oral Cancer
Published in Vaccines (Basel) (01-09-2022)“…Oral cancer is a significant non-communicable disease affecting both emergent nations and developed countries. Squamous cell carcinoma of the head and neck…”
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Lack of association between ACE I/D, NOS3 VNTR polymorphisms and drug toxicity of tacrolimus treated post-renal transplantation patients
Published in Journal of nephropharmacology (01-05-2020)“…Introduction : Tacrolimus is the most commonly used calcineurin inhibitor for renal transplant individuals. Genetic factors play a major role in allografts by…”
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Angiotensinogen gene polymorphisms and progression of chronic kidney disease in ADPKD patients
Published in Clinical and experimental nephrology (01-08-2016)“…Background Autosomal dominant polycystic kidney disease (ADPKD) is a multisystemic and progressive disorder characterized by cyst formation and kidney…”
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Assessing the Inhibitory Potential of Pregnenolone Sulfate on Pentraxin 3 in Diabetic Kidney Disease: A Molecular Docking and Simulation Study
Published in Journal of cellular biochemistry (30-09-2024)“…Diabetic Kidney Disease (DKD), a frequent consequence of diabetes, has substantial implications for both morbidity and mortality rates, prompting the…”
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Intestinal microbiome diversity of diabetic and non-diabetic kidney disease: Current status and future perspective
Published in Life sciences (1973) (01-03-2023)“…A significant portion of the health burden of diabetic kidney disease (DKD) is caused by both type 1 and type 2 diabetes which leads to morbidity and mortality…”
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Aldosterone synthase gene is not a major susceptibility gene for progression of chronic kidney disease in patients with autosomal dominant polycystic kidney disease
Published in Saudi journal of kidney diseases and transplantation (01-05-2017)“…Autosomal dominant polycystic kidney disease (ADPKD) is the most common heritable kidney disease and is characterized by bilateral renal cysts. Hypertension is…”
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10
Multi-omics insights and therapeutic implications in polycystic ovary syndrome: a review
Published in Functional & integrative genomics (01-06-2023)“…Polycystic ovary syndrome (PCOS) is a common gynecological disease that causes adverse effects in women in their reproductive phase. Nonetheless, the molecular…”
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Effect of flupirtine on the growth and viability of U373 malignant glioma cells
Published in Cancer biology & medicine (01-09-2013)“…Objective: Flupirtine is a non-opioid analgesic without antipyretic or antiphlogistic properties but with favorable tolerability in humans. "Ibis analgesic…”
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Endothelin 1 gene is not a major modifier of chronic kidney disease advancement among the autosomal dominant polycystic kidney disease patients
Published in Journal of nephropharmacology (2016)“…Autosomal dominant polycystic kidney disease (ADPKD) is characterized by the presence of numerous cysts in the kidney and manifest with various renal and…”
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13
Phytochemicals in Parkinson’s Disease: a Pathway to Neuroprotection and Personalized Medicine
Published in Cell biochemistry and biophysics (13-11-2024)“…Parkinson's disease (PD) is a complex neurodegenerative disorder marked by the progressive loss of dopaminergic neurons in the substantia nigra. While current…”
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Hormonal regulation in diabetes: Special emphasis on sex hormones and metabolic traits
Published in Advances in protein chemistry and structural biology (2024)“…Diabetes constitutes a significant global public health challenge that is rapidly reaching epidemic proportions. Among the non-communicable diseases, the…”
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Association between end‐stage diabetic nephropathy and MTHFR (C677T and A1298C) gene polymorphisms
Published in Nephrology (Carlton, Vic.) (01-02-2019)“…ABSTRACT Aim Methylenetetrahydrofolate reductase (MTHFR) is a regulatory enzyme of homocysteine metabolism. The C677T and A1298C polymorphism of the MTHFR gene…”
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Current updates on metabolites and its interlinked pathways as biomarkers for diabetic kidney disease: A systematic review
Published in Translational research : the journal of laboratory and clinical medicine (01-03-2024)“…Diabetic kidney disease (DKD) is a major microvascular complication of diabetes mellitus (DM) that poses a serious risk as it can lead to end-stage renal…”
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Benzopyrene elimination from the environment using graphitic carbon nitride-SnS nanocomposites
Published in Chemosphere (Oxford) (01-03-2024)“…Benzopyrene (BaP) stands as a potent polycyclic aromatic hydrocarbon (PAH) molecule, boasting five fused aromatic rings, making its way into the human food…”
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18
Sleep-associated insulin resistance promotes neurodegeneration
Published in Molecular biology reports (01-10-2023)“…Lifestyle modification can lead to numerous health issues closely associated with sleep. Sleep deprivation and disturbances significantly affect inflammation,…”
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Association of AT1R (A1166C) gene polymorphisms and hypertension: A study in south Indian population and meta-analysis
Published in Journal of renal injury prevention (28-04-2024)“…Introduction: Hypertension is a multi-factorial disease caused by several etiologies. It has been reported that hypertension has been linked to AT1R A1166C…”
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Next-generation biomarkers for prognostic and potential therapeutic enhancement in Triple negative breast cancer
Published in Critical reviews in oncology/hematology (01-09-2024)“…Triple-negative breast carcinoma (TNBC) is one of the most challenging subtypes of breast carcinoma and it has very limited therapeutic options as it is highly…”
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