Search Results - "Ramamoorthi Elangovan, Venkateswaran"

Developmental programming: adverse sexually dimorphic transcriptional programming of gestational testosterone excess in cardiac left ventricle of fetal sheep by Ramamoorthi Elangovan, Venkateswaran, Saadat, Nadia, Ghnenis, Adel, Padmanabhan, Vasantha, Vyas, Arpita K.

“…Adverse in-utero insults during fetal life alters offspring’s developmental trajectory, including that of the cardiovascular system. Gestational…”
Get full text

Presence of ovarian stromal aberrations after cessation of testosterone therapy in a transgender mouse model by Kinnear, Hadrian M., Hashim, Prianka H., Cruz, Cynthia Dela, Chang, Faith L., Rubenstein, Gillian, Nimmagadda, Likitha, Elangovan, Venkateswaran Ramamoorthi, Jones, Andrea, Brunette, Margaret A., Hannum, D. Ford, Li, Jun Z., Padmanabhan, Vasantha, Moravek, Molly B., Shikanov, Ariella

“…Some transmasculine individuals may be interested in pausing gender-affirming testosterone therapy and carrying a pregnancy. The ovarian impact of taking and…”
Get full text

Mechanical stress induces pre-B-cell colony-enhancing factor/NAMPT expression via epigenetic regulation by miR-374a and miR-568 in human lung endothelium by Adyshev, Djanybek M, Elangovan, Venkateswaran Ramamoorthi, Moldobaeva, Nurgul, Mapes, Brandon, Sun, Xiaoguang, Garcia, Joe G N

“…Increased lung vascular permeability and alveolar edema are cardinal features of inflammatory conditions such as acute respiratory distress syndrome (ARDS) and…”
Get full text

FGR-associated placental insufficiency and capillary angiogenesis involves disruptions in human placental miRNAs and mRNAs by Song, Wenhui, Guo, Qing, Puttabyatappa, Muraly, Elangovan, Venkateswaran Ramamoorthi, Wang, Jianping, Li, Fang, Liu, Fangfang, Bi, Xuejie, Li, Haiying, Fu, Guangping, Padmanabhan, Vasantha, Wu, XiaoHua

“…Fetal growth restriction (FGR) is one of the most common pregnancy complications culminating in adverse fetal outcome, including preterm birth, neonatal…”
Get full text

Endotoxin- and Mechanical Stress–Induced Epigenetic Changes in the Regulation of the Nicotinamide Phosphoribosyltransferase Promoter by Elangovan, Venkateswaran Ramamoorthi, Camp, Sara M., Kelly, Gabriel T., Desai, Ankit A., Adyshev, Djanybek, Sun, Xiaoguang, Black, Stephen M., Wang, Ting, Garcia, Joe G. N.

“…Mechanical ventilation, a lifesaving intervention for patients with acute respiratory distress syndrome (ARDS), also unfortunately contributes to excessive…”
Get full text

Abstract 4121970: Early to Mid-Gestational Testosterone Excess Sex-specifically Reprograms Cardiac Transcriptome and Metabolome Profiles of Sheep Fetuses by Alkhatib, Bashar, Ramamoorthi Elangovan, Venkateswaran, Cho, Kevin, Shriver, Leah, Patti, Gary, Padmanabhan, Vasantha, Vyas, Arpita

“…Abstract only Exposure of sheep to excess testosterone (T) from days 30-90 of gestation (term 147 days) perturbs maternal systemic lipidome in late gestation,…”
Get full text

Developmental programming: Impact of prenatal bisphenol-A exposure on liver and muscle transcriptome of female sheep by Puttabyatappa, Muraly, Saadat, Nadia, Elangovan, Venkateswaran Ramamoorthi, Dou, John, Bakulski, Kelly, Padmanabhan, Vasantha

“…Gestational Bisphenol A (BPA) exposure leads to peripheral insulin resistance, and hepatic and skeletal muscle oxidative stress and lipotoxicity during…”
Get full text

Developmental programming: Adipose depot-specific regulation of non-coding RNAs and their relation to coding RNA expression in prenatal testosterone and prenatal bisphenol-A -treated female sheep by Dou, John, Thangaraj, Soundara Viveka, Puttabyatappa, Muraly, Elangovan, Venkateswaran Ramamoorthi, Bakulski, Kelly, Padmanabhan, Vasantha

“…Inappropriate developmental exposure to steroids is linked to metabolic disorders. Prenatal testosterone excess or bisphenol A (BPA, an environmental estrogen…”
Get full text

A Transcription Start Site Map in Human Pancreatic Islets Reveals Functional Regulatory Signatures by Varshney, Arushi, Kyono, Yasuhiro, Elangovan, Venkateswaran Ramamoorthi, Wang, Collin, Erdos, Michael R, Narisu, Narisu, Albanus, Ricardo D'Oliveira, Orchard, Peter, Stitzel, Michael L, Collins, Francis S, Kitzman, Jacob O, Parker, Stephen C J

“…Identifying the tissue-specific molecular signatures of active regulatory elements is critical to understand gene regulatory mechanisms. Here, we identify…”
Get full text

Deficiency of the Deubiquitinase UCHL1 Attenuates Pulmonary Arterial Hypertension by Tang, Haiyang, Gupta, Akash, Morrisroe, Seth A, Bao, Changlei, Schwantes-An, Tae-Hwi, Gupta, Geetanjali, Liang, Shuxin, Sun, Yanan, Chu, Aiai, Luo, Ang, Ramamoorthi Elangovan, Venkateswaran, Sangam, Shreya, Shi, Yinan, Naidu, Samisubbu R, Jheng, Jia-Rong, Ciftci-Yilmaz, Sultan, Warfel, Noel A, Hecker, Louise, Mitra, Sumegha, Coleman, Anna W, Lutz, Katie A, Pauciulo, Michael W, Lai, Yen-Chun, Javaheri, Ali, Dharmakumar, Rohan, Wu, Wen-Hui, Flaherty, Daniel P, Karnes, Jason H, Breuils-Bonnet, Sandra, Boucherat, Olivier, Bonnet, Sebastien, Yuan, Jason X-J, Jacobson, Jeffrey R, Duarte, Julio D, Nichols, William C, Garcia, Joe G N, Desai, Ankit A

“…The ubiquitin-proteasome system regulates protein degradation and the development of pulmonary arterial hypertension (PAH), but knowledge about the role of…”
Get full text

The NAMPT promoter is regulated by mechanical stress, signal transducer and activator of transcription 5, and acute respiratory distress syndrome-associated genetic variants by Sun, Xiaoguang, Elangovan, Venkateswaran Ramamoorthi, Mapes, Brandon, Camp, Sara M, Sammani, Saad, Saadat, Laleh, Ceco, Ermelinda, Ma, Shwu-Fan, Flores, Carlos, MacDougall, Matthew S, Quijada, Hector, Liu, Bin, Kempf, Carrie L, Wang, Ting, Chiang, Eddie T, Garcia, Joe G N

“…Increased nicotinamide phosphoribosyltransferase (NAMPT) transcription is mechanistically linked to ventilator-induced inflammatory lung injury (VILI), with…”
Get full text

Abstract 20538: Nrf2 Signaling Ameliorates Ventilator-Induced Lung Inflammation by Wang, Ting, Jiang, Tao, Quijada, Hector, Mascarenhas, Joseph B, Ramamoorthi Elangovan, Venkateswaran, Hecker, Louise, Lussier, Yves A, Yuan, Jason X, Zhang, Donna D, Garcia, Joe G

“…Abstract only Ventilator-induced lung injury (VILI) is an acute lung injury that develops during mechanical ventilation with high tidal volume in patients in…”
Get full text

Genetic and Epigenetic Regulation of NAMPT/PBEF Expression in Human Lung Endothelium by Ramamoorthi Elangovan, Venkateswaran

“…Hypoxemia, pulmonary edema and persistent inflammation are cardinal features of acute respiratory distress syndrome (ARDS) and patients suffer from respiratory…”
Get full text