Search Results - "Ramalho, Leandra Náira Zambelli"
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Nicotinamide Nucleotide Transhydrogenase Is Essential for Adrenal Steroidogenesis: Clinical and In Vitro Lessons
Published in The journal of clinical endocrinology and metabolism (01-06-2023)“…Abstract Context Nicotinamide nucleotide transhydrogenase (NNT) acts as an antioxidant defense mechanism. NNT mutations cause familial glucocorticoid…”
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Effects of Prenatal Exposure to Aflatoxin B1: A Review
Published in Molecules (Basel, Switzerland) (02-12-2021)“…Aflatoxins are mycotoxins produced as secondary fungal metabolites. Among them, aflatoxin B1 (AFB1) stands out due to its genotoxic and mutagenic potential,…”
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The Dose‐Dependent Effect of Curcumin Supplementation on Inflammatory Response and Gut Microbiota Profile in High‐Fat Fed C57BL/6 Mice
Published in Molecular nutrition & food research (01-12-2023)“…Scope The prevalence of obesity has increased, with excessive consumption of high‐fat foods being one of the primary causes. Curcumin, a polyphenol extracted…”
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Biochemical analysis of human breast tissues using Fourier-transform Raman spectroscopy
Published in Journal of biomedical optics (01-09-2006)“…We employ Fourier-transform Raman spectroscopy to study normal and tumoral human breast tissues, including several subtypes of cancers. We analyzed 194 Raman…”
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The role of tumor hypoxia in MUC1-positive breast carcinomas
Published in Virchows Archiv : an international journal of pathology (01-10-2011)“…Mucin 1 (MUC1) is a glycoprotein that is expressed on apical cell membranes in a variety of normal tissues. MUC1 is involved in cell signaling, inhibition of…”
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Effect of Dietary Supplementation with Omega-3 Fatty Acid on the Generation of Regulatory T Lymphocytes and on Antioxidant Parameters and Markers of Oxidative Stress in the Liver Tissue of IL-10 Knockout Mice
Published in Nutrients (24-02-2024)“…chronic low-grade inflammation, or inflammaging, emerges as a crucial element in the aging process and is associated with cardiovascular and neurological…”
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Expression of B lymphocyte-induced maturation protein 1 (Blimp-1) in keratinocyte and cytokine signalling drives human Th17 response in psoriasis
Published in Archives of dermatological research (01-04-2023)“…Transcriptional factor B lymphocyte-induced maturation protein 1 (Blimp-1) is pivotally implicated in T helper 17 (Th17) cell differentiation. This study…”
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Curcuma supplementation in high-fat-fed C57BL/6 mice: no beneficial effect on lipid and glucose profile or prevention of weight gain
Published in European journal of nutrition (01-02-2020)“…Purpose This experimental study investigated the effects of curcuma supplementation on weight gain, Body Adiposity Index, glucose and lipid profile, and liver…”
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Xenogeneic Mesenchymal Stromal Cells Improve Wound Healing and Modulate the Immune Response in an Extensive Burn Model
Published in Cell transplantation (01-02-2016)“…Major skin burns are difficult to treat. Patients often require special care and long-term hospitalization. Besides specific complications associated with the…”
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Ex vivo model of human skin (hOSEC) for assessing the dermatokinetics of the anti-melanoma drug Dacarbazine
Published in European journal of pharmaceutical sciences (01-05-2021)“…•Development of a new methodology for assessing drug skin distribution.•Development of a bioanalytical HPLC method to quantify dacarbazine.•Evaluation of the…”
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Immunohistochemical Expression of p16, p53, and p63 in Colorectal Adenomas and Adenocarcinomas
Published in Diseases of the colon & rectum (01-05-2006)“…PURPOSE: METHODS: RESULTS: CONCLUSIONS:…”
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Human Antigen Leucocyte (HLA)-G and HLA-E are differentially expressed in pancreatic disorders
Published in Human immunology (01-11-2019)“…Little information is available regarding the expression of the immunomodulatory Human Leukocyte Antigen (HLA)-G and -E molecules in pancreatic disorders. To…”
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Phyllodes tumor with osteosarcomatous differentiation: a comparative immunohistochemical study between epithelial and mesenchymal cells
Published in Tumori (01-07-2006)“…Phyllodes tumor of the breast with osteosarcomatous differentiation is rare and very little is known about its molecular profile. An immunohistochemical panel…”
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Mitogen activated protein kinases SakAHOG1 and MpkC collaborate for Aspergillus fumigatus virulence
Published in Molecular microbiology (01-06-2016)“…Summary Here, we investigated which stress responses were influenced by the MpkC and SakA mitogen‐activated protein kinases of the high‐osmolarity glycerol…”
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HLA-G liver expression and HLA-G extended haplotypes are associated with chronic hepatitis C in HIV-negative and HIV-coinfected patients
Published in Clinical immunology (Orlando, Fla.) (01-08-2020)“…Chronic hepatitis C virus (HCV) infection induces liver damage and the HCV/Human Immunodeficiency Virus (HIV)-coinfection may further contribute to its…”
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Systemic oxidative profile after tumor removal and the tumor microenvironment in melanoma patients
Published in Cancer letters (01-06-2015)“…Highlights • There is a relationship between Breslow thickness and a systemic pro-oxidant status. • Oxidative changes induced by melanoma remain in the…”
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A novel type of C11orf95-LOC-RELA fusion in a grade II supratentorial ependymoma: report of a case with literature review
Published in Child's nervous system (01-04-2019)“…Background Ependymoma (EPN) is the third most common central nervous system tumor in childhood. Recent advances in the molecular classification of EPN revealed…”
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High osmolarity glycerol response PtcB phosphatase is important for Aspergillus fumigatus virulence
Published in Molecular microbiology (01-04-2015)“…Summary Aspergillus fumigatus is a fungal pathogen that is capable of adapting to different host niches and to avoid host defenses. An enhanced understanding…”
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Exposure to acetaminophen impairs vasodilation, increases oxidative stress and changes arterial morphology of rats
Published in Archives of toxicology (01-07-2019)“…Acetaminophen (APAP) is one of the most widely consumed drugs in the world. Studies have shown renal and hepatic damage as the direct result of high oxidative…”
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