Search Results - "Ramakrishna, Navin B."

ELABELA Is an Endogenous Growth Factor that Sustains hESC Self-Renewal via the PI3K/AKT Pathway by Ho, Lena, Tan, Shawn Y.X., Wee, Sheena, Wu, Yixuan, Tan, Sam J.C., Ramakrishna, Navin B., Chng, Serene C., Nama, Srikanth, Szczerbinska, Iwona, Chan, Yun-Shen, Avery, Stuart, Tsuneyoshi, Norihiro, Ng, Huck Hui, Gunaratne, Jayantha, Dunn, N. Ray, Reversade, Bruno

“…ELABELA (ELA) is a peptide hormone required for heart development that signals via the Apelin Receptor (APLNR, APJ). ELA is also abundantly secreted by human…”
Get full text

Specification of human germ cell fate with enhanced progression capability supported by hindgut organoids by Alves-Lopes, João Pedro, Wong, Frederick C.K., Tang, Walfred W.C., Gruhn, Wolfram H., Ramakrishna, Navin B., Jowett, Geraldine M., Jahnukainen, Kirsi, Surani, M. Azim

“…Human primordial germ cells (hPGCs), the precursors of sperm and eggs, are specified during weeks 2−3 after fertilization. Few studies on ex vivo and in vitro…”
Get full text

In preprints: towards reconstituting an ovary by Ramakrishna, Navin B, Alberio, Ramiro

Get full text

Who watches the watchmen? RNAi pathway-derived ribosomal small RNAs burgeon in absence of piRNAs by Ramakrishna, Navin B., Miska, Eric A.

“…Instead of causing immediate sterility, loss of the C. elegans PIWI protein PRG-1 leads to accumulated infertility after tens of generations. In this issue of…”
Get full text

Mouse primordial germ-cell-like cells lack piRNAs by Ramakrishna, Navin B., Battistoni, Giorgia, Surani, M. Azim, Hannon, Gregory J., Miska, Eric A.

“…PIWI-interacting RNAs (piRNAs) are small RNAs bound by PIWI-clade Argonaute proteins that function to silence transposable elements (TEs). Following mouse…”
Get full text

Epigenetic Regulation during Primordial Germ Cell Development and Differentiation by Ramakrishna, Navin B, Murison, Keir, Miska, Eric A, Leitch, Harry G

“…Germline development varies significantly across metazoans. However, mammalian primordial germ cell (PGC) development has key conserved landmarks, including a…”
Get more information

Transcriptional activity and epigenetic regulation of transposable elements in the symbiotic fungus Rhizophagus irregularis by Dallaire, Alexandra, Manley, Bethan F, Wilkens, Maya, Bista, Iliana, Quan, Clement, Evangelisti, Edouard, Bradshaw, Charles R, Ramakrishna, Navin B, Schornack, Sebastian, Butter, Falk, Paszkowski, Uta, Miska, Eric A

“…Arbuscular mycorrhizal (AM) fungi form mutualistic relationships with most land plant species. AM fungi have long been considered as ancient asexuals…”
Get full text

Staged profiling of sperm development in sync by Ramakrishna, Navin B., Surani, M. Azim

Get full text

The histone chaperone SPT2 regulates chromatin structure and function in Metazoa by Saredi, Giulia, Carelli, Francesco N., Rolland, Stéphane G. M., Furlan, Giulia, Piquet, Sandra, Appert, Alex, Sanchez-Pulido, Luis, Price, Jonathan L., Alcon, Pablo, Lampersberger, Lisa, Déclais, Anne-Cécile, Ramakrishna, Navin B., Toth, Rachel, Macartney, Thomas, Alabert, Constance, Ponting, Chris P., Polo, Sophie E., Miska, Eric A., Gartner, Anton, Ahringer, Julie, Rouse, John

“…Histone chaperones control nucleosome density and chromatin structure. In yeast, the H3–H4 chaperone Spt2 controls histone deposition at active genes but its…”
Get full text

Epigenetic resetting in the human germ line entails histone modification remodeling by Gruhn, Wolfram H, Tang, Walfred W C, Dietmann, Sabine, Alves-Lopes, João P, Penfold, Christopher A, Wong, Frederick C K, Ramakrishna, Navin B, Surani, M Azim

“…Epigenetic resetting in the mammalian germ line entails acute DNA demethylation, which lays the foundation for gametogenesis, totipotency, and embryonic…”
Get full text

ELABELA Is an Endogenous Growth Factor that Sustains hESC Self-Renewal via the PI3K/AKT Pathway by Ho, Lena, Tan, Shawn Y.X., Wee, Sheena, Wu, Yixuan, Tan, Sam J.C., Ramakrishna, Navin B., Chng, Serene C., Nama, Srikanth, Szczerbinska, Iwona, Chan, Yun-Shen, Avery, Stuart, Tsuneyoshi, Norihiro, Ng, Huck Hui, Gunaratne, Jayantha, Dunn, N. Ray, Reversade, Bruno

Get full text

Identifying the Alternative Receptor of ELABELA in hESCs by Chng, Serene, Tan, Sam J.C., Tan, Shawn Y.X., Ramakrishna, Navin B., Ho, Lena, Reversade, Bruno

Get full text