Search Results - "Ramakers, Geert M J"

Hyperinsulinemia in rats causes impairment of spatial memory and learning with defects in hippocampal synaptic plasticity by involvement of postsynaptic mechanisms by Kamal, Amer, Ramakers, Geert M. J., Gispen, Willem Hendrik, Biessels, Geert Jan, Al Ansari, Amer

“…In addition to its peripheral metabolic functions, insulin acts as a central neuromodulator and affects synaptic plasticity of the hippocampal neurons. In this…”
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On the interrelation between alcohol addiction–like behaviors in rats by Smeets, Johanna A. S., Minnaard, A. Maryse, Ramakers, Geert M. J., Adan, Roger A. H., Vanderschuren, Louk J. M. J., Lesscher, Heidi M. B.

“…Rationale Alcohol use disorder (AUD) is a complex, heterogeneous disorder that only occurs in a minority of alcohol users. Various behavioral constructs,…”
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Increased elasticity of sucrose demand during hyperdopaminergic states in rats by Minnaard, A. Maryse, Luijendijk, Mieneke C. M., Baars, Annemarie M., Drost, Lisa, Ramakers, Geert M. J., Adan, Roger A. H., Lesscher, Heidi M. B., Vanderschuren, Louk J. M. J.

“…Rationale Deficits in cost–benefit decision-making are a core feature of several psychiatric disorders, including substance addiction, eating disorders and…”
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Absence of Ret signaling in mice causes progressive and late degeneration of the nigrostriatal system by Kramer, Edgar R, Aron, Liviu, Ramakers, Geert M J, Seitz, Sabine, Zhuang, Xiaoxi, Beyer, Klaus, Smidt, Marten P, Klein, Rüdiger

“…Support of ageing neurons by endogenous neurotrophic factors such as glial cell line-derived neurotrophic factor (GDNF) and brain-derived neurotrophic factor…”
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Insulin modulates hippocampal activity‐dependent synaptic plasticity in a N‐methyl‐d‐aspartate receptor and phosphatidyl‐inositol‐3‐kinase‐dependent manner by Van Der Heide, Lars P., Kamal, Amer, Artola, Alain, Gispen, Willem Hendrik, Ramakers, Geert M. J.

“…Insulin and its receptor are both present in the central nervous system and are implicated in neuronal survival and hippocampal synaptic plasticity. Here we…”
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Slow Progressive Degeneration of Nigral Dopaminergic Neurons in Postnatal Engrailed Mutant Mice by Sgadò, Paola, Albéri, Lavinia, Gherbassi, Daniel, Galasso, Sherri L., Ramakers, Geert M. J., Alavian, Kambiz N., Smidt, Marten P., Dyck, Richard H., Simon, Horst H.

“…The homeobox transcription factors Engrailed-1 and Engrailed-2 are required for the survival of mesencephalic dopaminergic neurons in a cell-autonomous and…”
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Neonatal Exposure to Brominated Flame Retardant BDE-47 Reduces Long-Term Potentiation and Postsynaptic Protein Levels in Mouse Hippocampus by Milou M. L. Dingemans, Geert M. J. Ramakers, Fabrizio Gardoni, Regina G. D. M. van Kleef, Bergman, Åke, Monica Di Luca, van den Berg, Martin, Remco H. S. Westerink, Henk P. M. Vijverberg

“…Background: Increasing environmental levels of brominated flame retardants raise concern about possible adverse effects, particularly through early…”
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Announced reward counteracts the effects of chronic social stress on anticipatory behavior and hippocampal synaptic plasticity in rats by Kamal, Amer, Van der Harst, Johanneke E, Kapteijn, Chantal M, Baars, Annemarie J. M, Spruijt, Berry M, Ramakers, Geert M. J

“…Chronic stress causes insensitivity to rewards (anhedonia) in rats, reflected by the absence of anticipatory behavior for a sucrose-reward, which can be…”
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Stage-specific functions of Semaphorin7A during adult hippocampal neurogenesis rely on distinct receptors by Jongbloets, Bart C., Lemstra, Suzanne, Schellino, Roberta, Broekhoven, Mark H., Parkash, Jyoti, Hellemons, Anita J. C. G. M., Mao, Tianyi, Giacobini, Paolo, van Praag, Henriette, De Marchis, Silvia, Ramakers, Geert M. J., Pasterkamp, R. Jeroen

“…The guidance protein Semaphorin7A (Sema7A) is required for the proper development of the immune and nervous systems. Despite strong expression in the mature…”
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Insulin signaling in the central nervous system: learning to survive by van der Heide, Lars P, Ramakers, Geert M J, Smidt, Marten P

“…Insulin is best known for its role in peripheral glucose homeostasis. Less studied, but not less important, is its role in the central nervous system. Insulin…”
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Morphine withdrawal enhances constitutive μ-opioid receptor activity in the ventral tegmental area by Meye, Frank J, van Zessen, Ruud, Smidt, Marten P, Adan, Roger A H, Ramakers, Geert M J

“…μ-Opioid receptors (MORs) in the ventral tegmental area (VTA) are pivotally involved in addictive behavior. While MORs are typically activated by opioids, they…”
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Erratum to: Hyperinsulinemia in rats causes impairment of spatial memory and learning with defects in hippocampal synaptic plasticity by involvement of postsynaptic mechanisms by Kamal, Amer, Ramakers, Geert M. J., Gispen, Willem Hendrik, Biessels, Geert Jan

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Effect of chronic intracerebroventricular insulin administration in rats on the peripheral glucose metabolism and synaptic plasticity of CA1 hippocampal neurons by Kamal, Amer, Ramakers, Geert M.J, Gispen, Willem Hendrik, Biessels, Geert Jan

“…Abstract In this study we examined the effects of sustained intracerebroventricular insulin infusion on hippocampal synaptic plasticity in rats. Insulin was…”
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A Postsynaptic Transient K+Current Modulated by Arachidonic Acid Regulates Synaptic Integration and Threshold for LTP Induction in Hippocampal Pyramidal Cells by Geert M. J. Ramakers, Storm, Johan F.

“…Voltage-gated ion channels in the dendrites and somata of central neurons can modulate the impact of synaptic inputs. One of the ionic currents contributing to…”
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Long-lasting modulation of synaptic plasticity in rat hippocampus after early-life complex febrile seizures by Notenboom, Robbert G. E., Ramakers, Geert M. J., Kamal, Amer, Spruijt, Berry M., De Graan, Pierre N. E.

“…A small fraction of children with febrile seizures appears to develop cognitive impairments. Recent studies in a rat model of hyperthermia‐induced febrile…”
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Effects of neonatal exposure to the flame retardant tetrabromobisphenol-A, aluminum diethylphosphinate or zinc stannate on long-term potentiation and synaptic protein levels in mice by Hendriks, Hester S., Koolen, Lucas A. E., Dingemans, Milou M. L., Viberg, Henrik, Lee, Iwa, Leonards, Pim E. G., Ramakers, Geert M. J., Westerink, Remco H. S.

“…Brominated flame retardants such as tetrabromobisphenol-A (TBBPA) may exert (developmental) neurotoxic effects. However, data on (neuro)toxicity of…”
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Physiology of repetitive transcranial magnetic stimulation of the human brain by Hoogendam, Janna Marie, Ramakers, Geert M.J, Di Lazzaro, Vincenzo

“…During the last two decades, transcranial magnetic stimulation (TMS) has rapidly become a valuable method to investigate noninvasively the human brain. In…”
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Chemical LTD in the CA1 field of the hippocampus from young and mature rats by Kamal, Amer, Ramakers, Geert M. J., Urban, Ivan J. A., De Graan, Pierre N. E., Gispen, Willem Hendrik

“…Within the hippocampal formation, two forms of long‐lasting synaptic plasticity, long‐term potentiation (LTP) and long‐term depression (LTD), can be induced…”
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Cue and Reward Evoked Dopamine Activity Is Necessary for Maintaining Learned Pavlovian Associations by van Zessen, Ruud, Flores-Dourojeanni, Jacques P, Eekel, Timon, van den Reijen, Siem, Lodder, Bart, Omrani, Azar, Smidt, Marten P, Ramakers, Geert M J, van der Plasse, Geoffrey, Stuber, Garret D, Adan, Roger A H

“…Associating natural rewards with predictive environmental cues is crucial for survival. Dopamine (DA) neurons of the ventral tegmental area (VTA) are thought…”
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Phenotypic segregation of aphakia and Pitx3-null mutants reveals that Pitx3 deficiency increases consolidation of specific movement components by Kas, Martien J.H., van der Linden, Annemarie J.A., Oppelaar, Hugo, von Oerthel, Lars, Ramakers, Geert M.J., Smidt, Marten P.

“…Deficiency of the meso-diencephalic dopamine (mdDA) neuron specific transcription factor Pitx3 in aphakia ( ak) mice results in the loss of the substantia…”
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