Search Results - "Ramachandran, Vijayan"
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1
Identification of Small Molecule Inhibitors Targeting Phosphoserine Phosphatase: A Novel Target for the Development of Antiamoebic Drugs
Published in ACS omega (02-07-2024)“…Amoebiasis, a widespread disease caused by the protozoan parasite Entamoeba histolytica, poses challenges due to the adverse effects of existing antiamoebic…”
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2
Structure-based inhibitor screening of natural products against NSP15 of SARS-CoV-2 revealed thymopentin and oleuropein as potent inhibitors
Published in Journal of proteins and proteomics (2021)“…Coronaviruses are enveloped, non-segmented positive-sense RNA viruses with the largest genome among RNA viruses. Their genome contains a large replicase ORF…”
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3
Genetic manipulation of Leishmania donovani threonyl tRNA synthetase facilitates its exploration as a potential therapeutic target
Published in PLoS neglected tropical diseases (01-06-2018)“…Aminoacyl tRNA synthetases are central enzymes required for protein synthesis. These enzymes are the known drug targets in bacteria and fungi. Here, we for the…”
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4
Stigmatized properties and housing values: an exploratory study
Published in Journal of housing and the built environment (15-09-2019)“…The purpose of this research is to provide an understanding of the potential effects that stigmatized properties may have for potential house purchasers'…”
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5
Deciphering the interaction of benzoxaborole inhibitor AN2690 with connective polypeptide 1 (CP1) editing domain of Leishmania donovani leucyl-tRNA synthetase
Published in Journal of biosciences (01-12-2020)“…Leucyl-tRNA synthetases (LRS) catalyze the linkage of leucine with tRNA Leu . A large insertion CP1 domain (Connective Polypeptide 1) in LRS is responsible for…”
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Molecular characterization and antibacterial effect of endophytic actinomycetes Nocardiopsis sp. GRG1 (KT235640) from brown algae against MDR strains of uropathogens
Published in Bioactive materials (01-12-2016)“…Our study is to evaluate the potential bioactive compound of Nocardiopsis sp. GRG1 (KT235640) and its antibacterial activity against multi drug resistant…”
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Influence of aluminum workfunction and capping dielectric thickness on the performance of local back surface field solar cell using numerical simulation
Published in Solar energy (01-01-2017)“…[Display omitted] •For AlOx/SiNx stack, aluminum influence is overridden by high fixed charge density.•For SiOx/SiNx, surface recombination velocity is reduced…”
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8
Accuracy of Contact Resistivity Measurements for Electron-Selective Titanium Oxide Contacts in n-Type c-Si Solar Cell
Published in IEEE journal of photovoltaics (01-05-2021)“…Contact resistivity quantifies the charge transport barrier, which is one of the key parameters for choosing the carrier selective contact for silicon solar…”
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9
Study of Surface Passivation and Charge Transport Barriers in DASH Solar Cell
Published in IEEE journal of photovoltaics (01-09-2019)“…Dopant-free asymmetric heterocontact (DASH) solar cells have recently shown the potential for high efficiency with no toxic dopant gases. In this paper, we…”
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10
Surface passivation and carrier selectivity of the thermal-atomic-layer-deposited TiO2 on crystalline silicon
Published in Japanese Journal of Applied Physics (01-08-2017)“…Here, we demonstrate the use of an ultrathin TiO2 film as a passivating carrier-selective contact for silicon photovoltaics. The effective lifetime, surface…”
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11
Structural analysis of EhPSP in complex with 3-phosphoglyceric acid from Entamoeba histolytica reveals a basis for its lack of phosphoglycerate mutase activity
Published in International journal of biological macromolecules (01-05-2021)“…Entamoeba histolytica phosphoserine phosphatase (EhPSP), a regulatory enzyme in the serine biosynthetic pathway, is also a structural homolog of…”
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12
Temperature-dependent energy gain of bifacial PV farms: A global perspective
Published in Applied energy (15-10-2020)“…•Temperature-dependent energy-yield (YY) and LCOE favor bifacial over monofacial PV.•An irradiance criterion defines the necessary condition for positive…”
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13
Neuropharmacological and molecular docking studies of xanthones from Swertia corymbosa
Published in Journal of receptors and signal transduction (01-04-2018)“…Anxiety represents a public health problem consistently found to be the most prevalent class of mental disorders among people of all ages. Xanthones possess…”
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14
Antibiofilm effect of Nocardiopsis sp. GRG 1 (KT235640) compound against biofilm forming Gram negative bacteria on UTIs
Published in Microbial pathogenesis (01-05-2018)“…Urinary tract infections (UTIs) are diverse public health complication and caused by range of pathogens, however mostly Gram negative bacteria cause…”
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15
A unique aromatic cluster near the active site of H. pylori CPA is essential for catalytic function
Published in Biophysical journal (18-01-2022)“…Polyamines are essential for cell growth and proliferation. In plants and many bacteria, including Helicobacter pylori, the parent polyamine putrescine is only…”
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16
A unique aromatic cluster near the active site of H.pylori CPA is essential for catalytic function
Published in Biophysical journal (18-01-2022)“…Polyamines are essential for cell growth and proliferation. In plants and many bacteria, including Helicobacter pylori, the parent polyamine putrescine is only…”
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17
Crystal structure of O-Acetylserine sulfhydralase (OASS) isoform 3 from Entamoeba histolytica: Pharmacophore-based virtual screening and validation of novel inhibitors
Published in European journal of medicinal chemistry (15-04-2020)“…The l-cysteine is crucial for growth, survival, defense against oxidative stress, and pathogenesis of Entamoeba histolytica. The de novo biosynthesis of…”
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18
Crystal structure of UDP-N-acetylglucosamine-enolpyruvate reductase (MurB) from Mycobacterium tuberculosis
Published in Biochimica et biophysica acta. Proteins and proteomics (01-03-2018)“…The biosynthesis of UDP-N-acetylmuramic acid (UDP-MurNAc) by reduction of UDP-N-acetylglucosamine-enolpyruvate (UDP-GlcNAc-EP) in an NADPH and FAD-dependent…”
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19
Hole-Collection Mechanism in Passivating Metal-Oxide Contacts on Si Solar Cells: Insights From Numerical Simulations
Published in IEEE journal of photovoltaics (01-03-2018)“…Silicon heterojunction solar cells enable high conversion efficiencies, thanks to their passivating contacts which consist of layered stacks of intrinsic and…”
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20
MoOxbased hole selective contact - Inference from the Simulation
Published in 2020 47th IEEE Photovoltaic Specialists Conference (PVSC) (14-06-2020)“…Transition metal oxide-based carrier selective contacts are under intense research. In this work, we compare the two different set of material parameters of…”
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