Search Results - "Ramachandran, Gopika"

Hindlimb unloading induces time-dependent disruption of testicular histology in mice by Karim, Asima, Qaisar, Rizwan, Azeem, Muhammad, Jose, Josemin, Ramachandran, Gopika, Ibrahim, Zeinab Mohamed, Elmoselhi, Adel, Ahmad, Firdos, Abdel-Rahman, Wael M., Ranade, Anu V.

“…Mechanical unloading of the body in the hindlimb unloaded (HU) mice induces pathology in multiple organs, but the effects on testes are poorly characterized…”
Get full text

Suppression of endoplasmic reticulum stress restores renal microarchitecture in a mouse model of simulated microgravity by Ramachandran, Gopika, Elmoselhi, Adel B, Qaisar, Rizwan, Kamath, Deepika

“…ABSTRACT Background: Hindlimb-unloaded (HU) mice are animal models of simulated microgravity that exhibit pathological changes in several organs; however,…”
Get full text

Mitigating sarcoplasmic reticulum stress limits disuse-induced muscle loss in hindlimb unloaded mice by Khan, Amir Ali, Gul, Muhammad Tehsil, Karim, Asima, Ranade, Anu, Azeem, Muhammad, Ibrahim, Zeinab, Ramachandran, Gopika, Nair, Vidhya A., Ahmad, Firdos, Elmoselhi, Adel, Qaisar, Rizwan

“…Muscle disuse in the hindlimb unloaded (HU) mice causes significant atrophy and weakness. However, the cellular and molecular mechanisms driving disuse-muscle…”
Get full text

Mesenchymal stem cell transplant as an intervention to ameliorate disuse-induced muscle atrophy in a mouse model of simulated microgravity by Qaisar, Rizwan, Srinivas, Megna, Gul, Muhammad Tehsil, Khan, Amir Ali, Ranade, Anu, Jose, Josemin, Ramachandran, Gopika, Ebby, Suni, Ahmad, Firdos, Karim, Asima

“…The hindlimb unloaded (HU) mouse model exhibits disuse-induced muscle atrophy. However, effective interventions remain elusive. We investigated the therapeutic…”
Get full text

Suppression of endoplasmic reticulum stress prevents disuse muscle atrophy in a mouse model of microgravity by Ibrahim, Zeinab, Ramachandran, Gopika, El-Huneidi, Waseem, Elmoselhi, Adel, Qaisar, Rizwan

“…•Hindlimb unloaded mice exhibit muscle atrophy and weakness.•Hindlimb unloading causes elevated ER stress in muscle.•Inhibition of ER stress with 4-PBA reduces…”
Get full text

Pharmacological inhibition of endoplasmic reticulum stress mitigates testicular pathology in a mouse model of simulated microgravity by Ranade, Anu V., Khan, Amir Ali, Gul, Muhammad Tehsil, Jose, Josemin, Ramachandran, Gopika, Qaisar, Rizwan, Karim, Asima, Ahmad, Firdos, Abdel-Rahman, Wael M.

“…Simulated microgravity during hindlimb unloaded (HU) induces multi-organ pathologies in mice, including testicular dysfunction. However, a detailed…”
Get full text

Pharmacological inhibition of ER stress mitigates testicular pathology in hind‐limb unloaded mice by Ranade, Anu V., Qaisar, Rizwan, Khan, Amir A., Karim, Asima, Gul, Muhammed T., Azeem, Muhammad, Jose, Josemin, Ramachandran, Gopika, Ibrahim, Zainab, Nair, Vidhya, Elmoselhi, Adel, Rahman Hassan, Wael A.

“…Reduced physical activity and cephalic fluid shift are common occurrences in prolonged bed rest and space flight, and can lead to testicular dysfunction…”
Get full text