Search Results - "Ramachandran, Charanya"

SLC4A11 depletion impairs NRF2 mediated antioxidant signaling and increases reactive oxygen species in human corneal endothelial cells during oxidative stress by Guha, Sanjukta, Chaurasia, Sunita, Ramachandran, Charanya, Roy, Sanhita

“…Corneal endothelial dystrophy is a progressive disease with gradual loss of vision and characterized by degeneration and dysfunction of corneal endothelial…”
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Anti-fungal efficacy of combination of amphotericin B with colistin and gentamicin in McCarey-Kaufman corneal preservation medium by Kukutam, Sushmasri, Chaurasia, Sunita, Joseph, Joveeta, Roy, Sanhita, Ramachandran, Charanya, Kandibanda, Srinivas

“…Purpose: To curtail the potential of donor corneal tissue disseminating fungi to the recipient's eye, we evaluated the addition of amphotericin B to…”
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Safety and efficacy of McCarey-Kaufman medium supplemented with colistin (polymyxin E) and amphotericin B in inhibiting the multidrug-resistant Pseudomonas aeruginosa using an ex vivo donor corneal infection model by Sushmasri, Kukutam, Mishra, Priyasha, Roy, Sanhita, Joseph, Joveeta, Ramachandran, Charanya, Srinivas, Kandibanda, Chaurasia, Sunita

“…This study aimed to evaluate the efficacy and safety of McCarey-Kaufman (MK) medium supplemented with colistin and amphotericin B in inhibiting the growth of…”
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Effect of mitomycin-C on contraction and migration of human nasal mucosa fibroblasts: implications in dacryocystorhinostomy by Kumar, Vinay, Ali, Mohammad Javed, Ramachandran, Charanya

“…To determine the effect of mitomycin-C (MMC) on the contraction and migration of human nasal mucosal fibroblasts (HNMFs) in vitro in order to identify the…”
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An experimental study to evaluate the effect of polymixin E (Colistin) alone or in combination with gentamicin in McCarey-Kaufman corneal preservation medium on various drug resistant bacterial and fungal isolates by Sushmasri, K, Joseph, Joveeta, Chaurasia, Sunita, Ramachandran, Charanya, Roy, Sanhita

“…Purpose: To assess the efficacy of the addition of polymyxin E (colistin) in the McCarey-Kaufman (MK) corneal storage solution against multi-drug resistant…”
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Concise Review: The Coming of Age of Stem Cell Treatment for Corneal Surface Damage by Ramachandran, Charanya, Basu, Sayan, Sangwan, Virender S., Balasubramanian, Dorairajan

“…The cornea is a vital component of the eye because it provides approximately 70% of the refraction and focusing of incoming light. Being the outermost surface…”
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Formation and Disassembly of Adherens and Tight Junctions in the Corneal Endothelium: Regulation by Actomyosin Contraction by Ramachandran, Charanya, Srinivas, Sangly P

“…Purpose. To determine the role of actin cytoskeleton in the disassembly and reformation of adherens junctions (AJs) and tight junctions (TJs) in bovine corneal…”
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Proof-of-concept study of electrospun PLGA membrane in the treatment of limbal stem cell deficiency by Ramachandran, Charanya, Deshpande, Pallavi, Ortega, Ilida, Sefat, Farshid, McKean, Rob, Srivastava, Mala, MacNeil, Sheila, Basu, Sayan, Sangwan, Virender Singh

“…ObjectiveThe aim of this study was to assess the safety of poly-lactic co-glycolic acid (PLGA) electrospun membranes as carriers for limbal tissue explants for…”
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Evidence for persistent UV-induced DNA damage and altered DNA damage response in xeroderma pigmentosa patient corneas by Akepogu, Jacquelyn, Jakati, Saumya, Chaurasia, Sunita, Ramachandran, Charanya

“…Xeroderma pigmentosum (XP) is a rare genetic disorder characterized by injury to the ocular surface due to exposure to ultraviolet (UV) radiation. UV-induced…”
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In Vitro Expansion of Corneal Endothelial Cells for Clinical Application: Current Update by Hazra, Swatilekha, Sneha, Iskala V., Chaurasia, Sunita, Ramachandran, Charanya

“…Endothelial dysfunction is one of the leading causes of corneal blindness and one of the common indications for keratoplasty. At present, the standard of…”
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Use of Decellularized SMILE (Small-Incision Lenticule Extraction) Lenticules for Engineering the Corneal Endothelial Layer: A Proof-of-Concept by Hazra, Swatilekha, Akepogu, Jacquelyn, Krishna, Supriya, Pulipaka, SriRavali, Bagga, Bhupesh, Ramachandran, Charanya

“…To demonstrate the suitability of using decellularized SMILE (Small-incision Lenticule Extraction) lenticules for culturing and transplanting the corneal…”
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Evidence for persistent UV-induced DNA damage and altered DNA damage response in xeroderma pigmentosa patient corneas by Akepogu, Jacquelyn, Jakati, Saumya, Chaurasia, Sunita, Ramachandran, Charanya

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In Vitro Profiling of the Extracellular Matrix and Integrins Expressed by Human Corneal Endothelial Cells Cultured on Silk Fibroin-Based Matrices by Hazra, Swatilekha, Dey, Souradeep, Mandal, Biman B., Ramachandran, Charanya

“…Developing a scaffold for culturing human corneal endothelial (HCE) cells is crucial as an alternative cell therapeutic approach to bridge the growing gap…”
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In Vitro Culture of Human Corneal Endothelium on Non-Mulberry Silk Fibroin Films for Tissue Regeneration by Ramachandran, Charanya, Gupta, Prerak, Hazra, Swatilekha, Mandal, Biman B

“…The purpose of this study was to determine if non-mulberry varieties of silk are suitable for the culture of corneal endothelium (CE). Aqueous silk fibroin…”
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Simplifying corneal surface regeneration using a biodegradable synthetic membrane and limbal tissue explants by Deshpande, Pallavi, Ramachandran, Charanya, Sefat, Farshid, Mariappan, Indumathi, Johnson, Claire, McKean, Robert, Hannah, Melanie, Sangwan, Virender S, Claeyssens, Frederik, Ryan, Anthony J, MacNeil, Sheila

“…Abstract Currently, damage to the ocular surface can be repaired by transferring laboratory cultured limbal epithelial cells (LECs) to the cornea using donor…”
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Science and Art of Cell-Based Ocular Surface Regeneration by Singh, Vivek, Shukla, Sachin, Ramachandran, Charanya, Mishra, Dilip Kumar, Katikireddy, Kishore R, Lal, Ikeda, Chauhan, Sunil K, Sangwan, Virender S

“…The potential cause of blindness worldwide includes diseases of the cornea, ocular surface (limbal stem cell deficiency, allergic conjunctivitis, dry eye…”
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Effect of elevated intracellular cAMP levels on actomyosin contraction in bovine trabecular meshwork cells by Ramachandran, Charanya, Patil, Rajkumar V, Sharif, Najam A, Srinivas, Sangly P

“…Elevated cAMP in the trabecular meshwork (TM) cells increases the aqueous humor outflow facility. The authors investigated the mechanisms by which elevated…”
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Combination of microstereolithography and electrospinning to produce membranes equipped with niches for corneal regeneration by Ortega, Ilida, Sefat, Farshid, Deshpande, Pallavi, Paterson, Thomas, Ramachandran, Charanya, Ryan, Anthony J, MacNeil, Sheila, Claeyssens, Frederik

“…Corneal problems affect millions of people worldwide reducing their quality of life significantly. Corneal disease can be caused by illnesses such as Aniridia…”
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Histamine-induced myosin light chain phosphorylation breaks down the barrier integrity of cultured corneal epithelial cells by YING GUO, RAMACHANDRAN, Charanya, SATPATHY, Minati, SRINIVAS, Sangly P

“…To investigate changes in the phosphorylation of myosin light chain (MLC) in response to histamine and its effect on the barrier integrity of corneal…”
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Combination of Microstereolithography and Electrospinning to Produce Membranes Equipped with Niches for Corneal Regeneration by Ortega, Ílida, Sefat, Farshid, Deshpande, Pallavi, Paterson, Thomas, Ramachandran, Charanya, Ryan, Anthony J., MacNeil, Sheila, Claeyssens, Frederik

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