Search Results - "Ramón Y Cajal, T"

DNA copy number profiling reveals extensive genomic loss in hereditary BRCA1 and BRCA2 ovarian carcinomas by Kamieniak, M M, Muñoz-Repeto, I, Rico, D, Osorio, A, Urioste, M, García-Donas, J, Hernando, S, Robles-Díaz, L, Ramón y Cajal, T, Cazorla, A, Sáez, R, García-Bueno, J M, Domingo, S, Borrego, S, Palacios, J, van de Wiel, M A, Ylstra, B, Benítez, J, García, M J

“…Background: Few studies have attempted to characterise genomic changes occurring in hereditary epithelial ovarian carcinomas (EOCs) and inconsistent results…”
Get full text

SEOM clinical guideline thyroid cancer (2019) by Gallardo, E., Medina, J., Sánchez, J. C., Viúdez, A., Grande, E., Porras, I., Ramón y Cajal, T., Trigo, J., Iglesias, L., Capdevila, J.

“…Thyroid carcinoma is the most frequent endocrine malignancy and accounts for around 3% of global cancer incidence. Different histologies and clinical scenarios…”
Get full text

Impact of CYP2D6 polymorphisms in tamoxifen adjuvant breast cancer treatment by Ramón y Cajal, T, Altés, A, Paré, L, del Rio, E, Alonso, C, Barnadas, A, Baiget, M

“…The aim of this study is to evaluate the impact of CYP2D6 genotyping in predicting disease-free survival and toxicity in breast cancer patients treated with…”
Get full text

Identification of a founder EPCAM deletion in Spanish Lynch syndrome families by Mur, P., Pineda, M., Romero, A., del Valle, J., Borràs, E., Canal, A., Navarro, M., Brunet, J., Rueda, D., Ramón y Cajal, T., Lázaro, C., Caldés, T., Blanco, I., Soto, J.L., Capellá, G.

“…Germline deletions at the 3′‐end of EPCAM have been involved in the etiology of Lynch syndrome (LS). The aim of this study was to characterize at the molecular…”
Get full text

SEOM clinical guidelines in hereditary breast and ovarian cancer (2019) by González-Santiago, S., Ramón y Cajal, T., Aguirre, E., Alés-Martínez, J. E., Andrés, R., Balmaña, J., Graña, B., Herrero, A., Llort, G., González-del-Alba, A.

“…Mutations in BRCA1 and BRCA2 high penetrance genes account for most hereditary breast and ovarian cancer, although other new high-moderate penetrance genes…”
Get full text

Germline ATM mutational analysis in BRCA1/BRCA2 negative hereditary breast cancer families by MALDI-TOF mass spectrometry by Graña, B., Fachal, L., Darder, E., Balmaña, J., Ramón y Cajal, T., Blanco, I., Torres, A., Lázaro, C., Diez, O., Alonso, C., Santamariña, M., Velasco, A., Teulé, A., Lasa, A., Blanco, A., Izquierdo, A., Borràs, J., Gutiérrez-Enríquez, S., Vega, A., Brunet, J.

“…Biallelic inactivation of ATM gene causes the rare autosomal recessive disorder Ataxia-telangiectasia (A-T). Female relatives of A-T patients have a two-fold…”
Get full text

Consensus on the management of advanced radioactive iodine-refractory differentiated thyroid cancer on behalf of the Spanish Society of Endocrinology Thyroid Cancer Working Group (GTSEEN) and Spanish Rare Cancer Working Group (GETHI) by Capdevila, J., Galofré, J. C., Grande, E., Zafón Llopis, C., Ramón y Cajal Asensio, T., Navarro González, E., Jiménez-Fonseca, P., Santamaría Sandi, J., Gómez Sáez, J. M., Riesco Eizaguirre, G.

“…Thyroid cancer is the single most prevalent endocrine malignancy; differentiated thyroid cancer (DTC) accounts for more than 90 % of all malignancies and its…”
Get full text

Factors associated with anxiety and depression in cancer patients prior to initiating adjuvant therapy by Jimenez-Fonseca, P., Calderón, C., Hernández, R., Ramón y Cajal, T., Mut, M., Ramchandani, A., Donnay, O., Carmona-Bayonas, A.

“…Objective Anxiety and depression affect cancer patients’ quality of life. Our objectives were to determine the prevalence of anxiety and depression and analyze…”
Get full text

Copy number variations are not modifiers of phenotypic expression in a pair of identical twins carrying a BRCA1 mutation by Lasa, A, Ramón y Cajal, T, Llort, G, Suela, J, Cigudosa, J. C, Cornet, M, Alonso, C, Barnadas, A, Baiget, M

“…Mutations in BRCA1 and BRCA2 genes confer a high risk of breast and ovarian cancer but the incomplete penetrance of these mutations suggests that other genetic…”
Get full text

996: Prevalence of germline MUTYH mutations among Lynch-like syndrome patients by Vargas, G, Navarro, M, González, S, Brunet, J, Ramón y Cajal, T, Balmaña, J, Lázaro, C, Blanco, I, Pineda, M, Capellá, G

Get full text

Association of BRCA1 germline mutations in young onset triple-negative breast cancer (TNBC) by Andrés, R., Pajares, I., Balmaña, J., Llort, G., Ramón y Cajal, T., Chirivella, I., Aguirre, E., Robles, L., Lastra, E., Pérez-Segura, P., Bosch, N., Yagüe, C., Lerma, E., Godino, J., Miramar, M. D., Moros, M., Astier, P., Saez, B., Vidal, M. J., Arcusa, A., Ramón y Cajal, S., Calvo, M. T., Tres, A.

“…Background BRCA1-associated breast cancers have been associated to a triple-negative phenotype. The prevalence of BRCA1 germline mutations in young onset TNBC…”
Get full text

Founder effect of a pathogenic MSH2 mutation identified in Spanish families with Lynch syndrome by Menéndez, M, Castellví-Bel, S, Pineda, M, De Cid, R, Muñoz, J, González, S, Teulé, À, Balaguer, F, Ramón y Cajal, T, Reñé, Josep M., Blanco, I, Castells, A, Capellà, G

“…Menéndez M, Castellví‐Bel S, Pineda M, de Cid R, Muñoz J, González S, TeuléÀ, Balaguer F, Ramón y Cajal T, Maria Reñé J, Blanco I, Castells A, Capellà G…”
Get full text

Hereditary pancreatic cancer: molecular bases and their application in diagnosis and clinical management. A guideline of the TTD group by Segura, P. Pérez, Ponce, C. Guillén, Ramón y Cajal, T., Blanch, R. Serrano, Aranda, E.

“…Pancreatic carcinoma (PC) represents the fourth leading cause of cancer death in Spain with a death rate of 2,400 males and 2,000 females per year. Poor…”
Get full text

Consensus on management of advanced medullary thyroid carcinoma on behalf of the Working Group of Thyroid Cancer of the Spanish Society of Endocrinology (SEEN) and the Spanish Task Force Group for Orphan and Infrequent Tumors (GETHI) by Grande, E., Santamaría Sandi, J., Capdevila, J., Navarro González, E., Zafón Llopis, C., Ramón y Cajal Asensio, T., Gómez Sáez, J. M., Jiménez-Fonseca, P., Riesco-Eizaguirre, G., Galofré, J. C.

“…Background Of all thyroid cancers, <5 % are medullary (MTC). It is a well-characterized neuroendocrine tumor arising from calcitonin-secreting C cells, and RET…”
Get full text

Spanish consensus for the management of patients with anaplastic cell thyroid carcinoma by Jiménez-Fonseca, P., Gómez Saez, J. M., Santamaria Sandi, J., Capdevila, J., Navarro Gonzalez, E., Zafon Llopis, C., Ramón y Cajal Asensio, T., Riesco-Eizaguirre, G., Grande, E., Galofré, J. C.

“…Anaplastic thyroid cancer (ATC) is the most aggressive solid tumor and almost uniformly lethal in humans. The Boards of the Thyroid Cancer Group of the Spanish…”
Get full text

Targeted prostate cancer screening in men with mutations in BRCA1 and BRCA2 detects aggressive prostate cancer: preliminary analysis of the results of the IMPACT study by Mitra, Anita V., Bancroft, Elizabeth K., Barbachano, Yolanda, Page, Elizabeth C., Foster, C. S., Jameson, C., Mitchell, G., Lindeman, G. J., Stapleton, A., Suthers, G., Evans, D. G., Cruger, D., Blanco, I., Mercer, C., Kirk, J., Maehle, L., Hodgson, S., Walker, L., Izatt, L., Douglas, F., Tucker, K., Dorkins, H., Clowes, V., Male, A., Donaldson, A., Brewer, C., Doherty, R., Bulman, B., Osther, P. J., Salinas, M., Eccles, D., Axcrona, K., Jobson, I., Newcombe, B., Cybulski, C., Rubinstein, W. S., Buys, S., Townshend, S., Friedman, E., Domchek, S., Ramon y Cajal, T., Spigelman, A., Teo, S. H., Nicolai, N., Aaronson, N., Ardern‐Jones, A., Bangma, C., Dearnaley, D., Eyfjord, J., Falconer, A., Grönberg, H., Hamdy, F., Johannsson, O., Khoo, V., Kote‐Jarai, Z., Lilja, H., Lubinski, J., Melia, J., Moynihan, C., Peock, S., Rennert, G., Schröder, F., Sibley, P., Suri, M., Wilson, P., Bignon, Y. J., Strom, S., Tischkowitz, M., Liljegren, A., Ilencikova, D., Abele, A., Kyriacou, K., van Asperen, C., Kiemeney, L., Easton, D. F., Eeles, Rosalind A.

“…Study Type – Diagnostic (validating cohort)
Level of Evidence 1b What’s known on the subject? and What does the study add? Scientists have found a number of…”
Get full text

Prognostic gene expression signature for high-grade serous ovarian cancer by Intermaggio, M.P., Leong, H.S., Chen, S., Elatre, W., Gilks, B., Volchek, M., Wang, C., Mackenzie, R., George, J., Bowtell, D., Chenevix-Trench, G., Green, A., Gertig, D., Fereday, S., Moore, S., Hung, J., Harrap, K., Malt, M., Robertson, R., Maidens, J., Jayde, V., Mamers, P., Schmidt, T., Ball, C., Bilic, Sanela, Stuart-Harris, R., Clingan, P., Glasgow, A., Shannon, J., Young, B., Robertson, G., Carter, J., Dalrymple, C., Russell, P., Links, M., Jaworski, R., Crandon, A., Horwood, K., Obermair, A., Wyld, D., Davy, M., Dodd, T., Healy, T., Pittman, K., Henderson, D., Pierdes, J., Brown, B., Hyde, S., Healy, D., McNealage, J., Simpson, I., Fox, S., Lade, S., Loughrey, M., Neesham, D., Bell, R., Ng, L.F., Whiteman, D., Fereday, S., Steed, H., Koziak, J.M., Goranova, T., Silva De Silva, D., Ramón y Cajal, T., García-Donas, J., Rodriguez, G.C., Harris, H.R., Greene, C.S., Zelaya, R.A., Sinn, P., Menkiszak, J., Pearce, C.L., Rhenius, V., Piskorz, A.M., Sharma, R., Johnatty, S.E., Larson, M.C., Luk, H., Hernandez, B.Y., Thompson, P.J., Sherman, M.E., Bodelon, C., Lewsley, L.A., Banerjee, S.N., Stronach, E.A., Haluska, P., Ray-Coquard, I., Winterhoff, B., Slamon, D., Levine, D.A., Menon, U., Goodman, M.T., Schildkraut, J.M., Brown, R., Berchuck, A., Chenevix-Trench, G., deFazio, A., Beeghly-Fadiel, A., Fasching, P.A., Orsulic, S.

“…Median overall survival (OS) for women with high-grade serous ovarian cancer (HGSOC) is ∼4 years, yet survival varies widely between patients. There are no…”
Get full text

266 Predictive and prognostic value of microtubule-associated protein-tau and classes I to IV b-tubulin isotypes in locally advancedbreast cancer by Tibau, A, López Vilar ó, L, Anguera, G, Virgili, A, Pérez-Olabarria, M, Vázquez, T, Gich, I, Alonso, C, Ojeda, B, Ramoń y Cajal, T, Murata, P, Enrique, L, Escuin, D, Barnadas, A

Get full text

8113 POSTER Anxiety, depression and quality of life in patients undergoing genetic testing for BRCA in a Spanish multicentre cohort (IMASS collaborative group) by Mensa, I, Fortuny, D, Brunet, J, Ramón y Cajal, T, Torres, A, Ramírez, N, Balmaña, J

Get full text

734P Kidney manifestations in patients with hereditary leiomyomatosis and renal cell cancer syndrome (LHRCC) in Spain by Sanchez, A.B., Teule, A., Lastra, E., Balmana, J., Robles, L., García, J.D.D., Ramón y Cajal, T., Llort, G., Fonfria, M., Robledo, M., Castillejo, A., Duran, M., Zuñiga, A., Gómez, L., Garcés, E. Grau, López, A., Bosquet-Sanz, M., Barberá, V., Soto, J.L.

Get full text