Search Results - "Ramírez Ramírez, Maritza"
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A Novel Combination of Sotorasib and Metformin Enhances Cytotoxicity and Apoptosis in KRAS-Mutated Non-Small Cell Lung Cancer Cell Lines through MAPK and P70S6K Inhibition
Published in International journal of molecular sciences (22-02-2023)“…Novel inhibitors of KRAS with G12C mutation (sotorasib) have demonstrated short-lasting responses due to resistance mediated by the AKT-mTOR-P70S6K pathway. In…”
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Clinical Impact of the COVID‐19 Pandemic in Mexican Patients with Thoracic Malignancies
Published in The oncologist (Dayton, Ohio) (01-12-2021)“…Background Accumulated evidence indicates that patients with lung cancer are a vulnerable population throughout the pandemic. Limited information is available…”
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Evaluation of a risk-sharing agreement for atezolizumab treatment in patients with non-small cell lung cancer: a strategy to improve access in low-income countries
Published in The oncologist (Dayton, Ohio) (19-10-2024)“…Using immune checkpoint inhibitors (IO) is a promising approach to maximize clinical benefits for patients with non-small cell lung cancer (NSCLC). PD-L1…”
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Risk of Developing Checkpoint Immune Pneumonitis and Its Effect on Overall Survival in Non-small Cell Lung Cancer Patients Previously Treated With Radiotherapy
Published in Frontiers in oncology (29-09-2020)“…Immune checkpoint inhibitor-related pneumonitis (ICIP) is a potentially life threatening immune-related adverse event (irAE), especially in non-small cell lung…”
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Early Incorporation to Palliative Care (EPC) in Patients With Advanced Non-Small Cell Lung Cancer: The PACO Randomized Clinical Trial
Published in The oncologist (Dayton, Ohio) (03-10-2024)“…Patients with non-small cell lung cancer (NSCLC) experience a considerable disease burden, evident in symptomatic and psychological spheres. Advanced cancer…”
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Cost-effectiveness analysis of first and second-generation EGFR tyrosine kinase inhibitors as first line of treatment for patients with NSCLC harboring EGFR mutations
Published in BMC cancer (01-09-2020)“…Tyrosine-kinase inhibitors (TKIs) have become the cornerstone treatment of patients with non-small cell lung cancer that harbor oncogenic EGFR mutations. The…”
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A high number of co-occurring genomic alterations detected by NGS is associated with worse clinical outcomes in advanced EGFR-mutant lung adenocarcinoma: Data from LATAM population
Published in Lung cancer (Amsterdam, Netherlands) (01-12-2022)“…•Co-occurring genomic alterations at diagnosis might represent de novo and primary resistance mechanisms to tyrosine kinase inhibitors (TKIs) in advanced…”
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Impact of KRASG12D subtype and concurrent pathogenic mutations on advanced non-small cell lung cancer outcomes
Published in Clinical & translational oncology (01-04-2024)“…Purpose Mutations in the Kirsten rat sarcoma viral (KRAS) oncogene constitute a significant driver of lung adenocarcinoma, present in 10–40% of patients, which…”
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LKB1 Loss Assessed by Immunohistochemistry as a Prognostic Marker to First-Line Therapy in Advanced Non-Small-Cell Lung Cancer
Published in Current oncology (Toronto) (26-12-2022)“…(1) Background: Liver kinase B1 (LKB1) is a tumor suppressor gene involved in cell growth and metabolism. However, its alterations are not routinely assessed…”
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Attitudes toward mathematics and virtual teaching of students in the context of COVID-19: validation and reliability of instruments
Published in Frontiers in education (Lausanne) (23-10-2024)“…BackgroundThere are few instruments to assess attitudes toward mathematics and virtual teaching; Likewise, there are methodological limitations to study this…”
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Relationship between attitudes toward mathematics and perceptions of virtual teaching in the COVID-19 context
Published in Frontiers in education (Lausanne) (02-07-2024)“…BackgroundThe shift to virtual education from 2019 to 2021 in response to COVID-19 necessitated both teachers and students to adapt to new technological…”
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Efficacy, Safety, and Cost-Minimization Analysis of Continuous Infusion of Low-Dose Gemcitabine Plus Cisplatin in Patients With Unresectable Malignant Pleural Mesothelioma
Published in Frontiers in oncology (20-04-2021)“…Malignant pleural mesothelioma (MPM) is rare and aggressive neoplasia, with a poor prognosis; furthermore, the monetary cost of its treatment represents a…”
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The Evolution of Clinically Aggressive Triple-Negative Breast Cancer Shows a Large Mutational Diversity and Early Metastasis to Lymph Nodes
Published in Cancers (12-10-2021)“…In triple-negative breast cancer (TNBC), only 30% of patients treated with neoadjuvant chemotherapy achieve a pathological complete response after treatment…”
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La infografía digital periodística y su aporte a la prensa escolar
Published in KEPES, Grupo de estudio en Diseno Visual (01-01-2020)“…Esta investigación indaga por el aporte de la infografía digital periodística a la prensa escolar. Se realizó a través de revisión bibliográfica y entrevistas…”
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Comprehensive Genomic Profile of Heterogeneous Long Follow-Up Triple-Negative Breast Cancer and Its Clinical Characteristics Shows DNA Repair Deficiency Has Better Prognostic
Published in Genes (19-11-2020)“…Triple-negative breast cancer (TNBC) presents a marked diversity at the molecular level, which promotes a clinical heterogeneity that further complicates…”
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Evaluación de la formación ética en la psicología colombiana
Published in Avances en psicología latinoamericana (2021)“…Este artículo presenta los resultados de una investigación dirigida a evaluar la formación ética recibida en los estudios de psicología, que hizo parte del…”
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Hydrodynamic conditions induce changes in secretion level and glycosylation patterns of Von Willebrand factor (vWF) in endothelial cells
Published in Journal of bioscience and bioengineering (01-04-2010)“…The effect of low-speed agitation on the level of secretion and glycosylation patterns of the Von Willebrand factor in endothelial cells cultured in 6-cm Petri…”
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Residuos de plaguicidas en mora (Rubus glaucus Benth.) en el Valle del Cauca, Colombia
Published in Agronomía mesoamericana (01-05-2022)“…Introducción. La mora (Rubus glaucus) es una fruta muy susceptible a la contaminación por residuos de plaguicidas en su etapa de producción. Por tal razón, los…”
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Diversas metodologías en los procesos de enseñanzas de aprendizajes
Published in Revista multi-ensayos (03-12-2019)“…Efectuar diversas metodologías en las enseñanzas de aprendizajes en la educación superior, permite que los estudiantes se sientan motivados, desarrollen…”
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Marketing Online: propuesta de valor y su efecto sobre la lealtad del consumidor
Published in Revista Scientific (05-05-2022)“…La investigación tiene objetivo de analizar actividades de marketing en redes sociales de marcas más reconocidas de entidades financieras ecuatorianas, siendo…”
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