Search Results - "Ramírez‐Apán, María Teresa"

Cytotoxic Activity and Structure–Activity Relationship of Triazole‐Containing Bis(Aryl Ether) Macrocycles by Hernández‐Vázquez, Eduardo, Chávez‐Riveros, Alejandra, Romo‐Pérez, Adriana, Ramírez‐Apán, María Teresa, Chávez‐Blanco, Alma D., Morales‐Bárcenas, Rocío, Dueñas‐González, Alfonso, Miranda, Luis D.

“…Cancer continues to be a worldwide health problem. Certain macrocyclic molecules have become attractive therapeutic alternatives for this disease because of…”
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Synthesis and cytotoxic evaluation of protoanemonin and three brominated derivatives by Villegas Pañeda, Alejandra Guadalupe, Ramírez Apan, María Teresa Obdulia

“…The protoanemonin, a natural furanone, was synthesized from (Z)-4-bromo-5-(bromomethylene)-furan-2(5H)-one by a reductive dehalogenation reaction with zinc…”
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Synthesis of non-cytotoxic poly(ester-amine) dendrimers as potential solubility enhancers for drugs: methotrexate as a case study by Soto-Castro, Delia, Cruz-Morales, Jorge A, Ramírez Apan, María Teresa, Guadarrama, Patricia

“…This study describes the synthesis of two new families of dendrimers based on the esterification of N-alkylated 3-amine-1-propanol with two different cores,…”
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Full Structural Characterization of Homoleptic Complexes of Diacetylcurcumin with Mg, Zn, Cu, and Mn: Cisplatin-level Cytotoxicity in Vitro with Minimal Acute Toxicity in Vivo by Meza-Morales, William, Estévez-Carmona, M Mirian, Alvarez-Ricardo, Yair, Obregón-Mendoza, Marco A, Cassani, Julia, Ramírez-Apan, María Teresa, Escobedo-Martínez, Carolina, Soriano-García, Manuel, Reynolds, William F, Enríquez, Raúl G

“…At the present time, scientists place a great deal of effort worldwide trying to improve the therapeutic potential of metal complexes of curcumin and…”
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Triterpenes from Garcia parviflora. Cytotoxic Evaluation of Natural and Semisynthetic Friedelanes by Reyes, Blanca M, Ramírez-Apan, María Teresa, Toscano, Rubén A, Delgado, Guillermo

“…Three new friedelane-type triterpenes, 1,2-dehydro-2,3-secofriedelan-3-oic acid (1), 1β-hydroxyfriedelin (2), and 3β-hydroxyfriedelan-23-oic acid (3), and the…”
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5,6-Dihydropyrrolo[2,1-a]isoquinolines as Alternative of New Drugs with Cytotoxic Activity by Chávez-Santos, Rosa María, Reyes-Gutiérrez, Paul Eduardo, Torres-Ochoa, Rubén Omar, Ramírez-Apan, María Teresa, Martínez, Roberto

“…In this study, the pyrrolo[2,1-a]isoquinolines 4a–n were synthesized in good yields in a three steps synthesis from the corresponding α,β-unsaturated esters…”
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Retro-Curcuminoids as Mimics of Dehydrozingerone and Curcumin: Synthesis, NMR, X-ray, and Cytotoxic Activity by Obregón-Mendoza, Marco A, Estévez-Carmona, María Mirian, Hernández-Ortega, Simón, Soriano-García, Manuel, Ramírez-Apan, María Teresa, Orea, Laura, Pilotzi, Hugo, Gnecco, Dino, Cassani, Julia, Enríquez, Raúl G

“…Curcumin and its derivatives have been extensively studied for their remarkable medicinal properties, and their chemical synthesis has been an important step…”
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Solubilization and anticancer-activity enhancement of Methotrexate by novel dendrimeric nanodevices synthesized in one-step reaction by Soto-Castro, Delia, Cruz-Morales, Jorge A., Apan, María Teresa Ramírez, Guadarrama, Patricia

“…Dual scenario of drug transport Nanodevices containing MTX (anticancer drug) and FA (metabolite) were synthesized and tested in cell growth inhibition…”
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Role of bentonite clays on cell growth by Cervini-Silva, Javiera, Ramírez-Apan, María Teresa, Kaufhold, Stephan, Ufer, Kristian, Palacios, Eduardo, Montoya, Ascención

“…Bentonites, naturally occurring clays, are produced industrially because of their adsorbent capacity but little is known about their effects on human health…”
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Synthesis of theophylline-based iridium(I) N-heterocyclic carbene complexes including fluorinated-thiophenolate ligands. Preliminary evaluation of their in vitro anticancer activity by Eslava-Gonzalez, Itzel, Valdés, Hugo, Teresa Ramírez-Apan, María, Hernandez-Ortega, Simón, Rosario Zermeño-Ortega, Miriam, Avila-Sorrosa, Alcives, Morales-Morales, David

“…[Display omitted] •Three theophylline-based Ir(I) N-heterocyclic carbene complexes were synthesized.•The complexes have excellent cytotoxic activities against…”
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The Homoleptic Curcumin–Copper Single Crystal (ML2): A Long Awaited Breakthrough in the Field of Curcumin Metal Complexes by Arenaza-Corona, Antonino, Obregón-Mendoza, Marco A., Meza-Morales, William, Ramírez-Apan, María Teresa, Nieto-Camacho, Antonio, Toscano, Rubén A., Pérez-González, Leidys L., Sánchez-Obregón, Rubén, Enríquez, Raúl G.

“…The first single crystal structure of the homoleptic copper (II) ML2 complex (M=Cu (II), L = curcumin) was obtained and its structure was elucidated by X-ray…”
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In Vitro Evaluation of the Potential Pharmacological Activity and Molecular Targets of New Benzimidazole-Based Schiff Base Metal Complexes by Aragón-Muriel, Alberto, Liscano, Yamil, Upegui, Yulieth, Robledo, Sara M, Ramírez-Apan, María Teresa, Morales-Morales, David, Oñate-Garzón, Jose, Polo-Cerón, Dorian

“…Metal-based drugs, including lanthanide complexes, have been extremely effective in clinical treatments against various diseases and have raised major interest…”
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Anti-inflammatory, anti-bacterial, and cytotoxic activity of fibrous clays by Cervini-Silva, Javiera, Nieto-Camacho, Antonio, Ramírez-Apan, María Teresa, Gómez-Vidales, Virginia, Palacios, Eduardo, Montoya, Ascención, Ronquillo de Jesús, Elba

“…•Fibrous clays serve as an effective anti-inflammatory.•Cellular-level signals respond exclusively to an early exposure to clay.•Anti-inflammatory activity was…”
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Synthesis, Cytotoxic Activity and In Silico Study of Novel Dihydropyridine Carboxylic Acids Derivatives by Ballinas-Indilí, Ricardo, Nicolás-Vázquez, María Inés, Martínez, Joel, Ramírez-Apan, María Teresa, Álvarez-Toledano, Cecilio, Toscano, Alfredo, Hernández-Rodríguez, Maricarmen, Mera Jiménez, Elvia, Miranda Ruvalcaba, René

“…To aid the possible prevention of multidrug resistance in tumors and cause lower toxicity, a set of sixteen novel dihydropyridine carboxylic acids derivatives…”
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Homoleptic Complexes of Heterocyclic Curcuminoids with Mg(II) and Cu(II): First Conformationally Heteroleptic Case, Crystal Structures, and Biological Properties by Meza-Morales, William, Alejo-Osorio, Yuritzi, Alvarez-Ricardo, Yair, Obregón-Mendoza, Marco A, Machado-Rodriguez, Juan C, Arenaza-Corona, Antonino, Toscano, Rubén A, Ramírez-Apan, María Teresa, Enríquez, Raúl G

“…We report herein the synthesis and characterization of three heterocyclic curcuminoid ligands and their homoleptic metal complexes with magnesium and copper…”
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First Gallium and Indium Crystal Structures of Curcuminoid Homoleptic Complexes: All-Different Ligand Stereochemistry and Cytotoxic Potential by Meza-Morales, William, Alvarez-Ricardo, Yair, Pérez-González, Leidys L., Tavera-Hernández, Rosario, Ramírez-Apan, María Teresa, Toscano, Rubén A., Sánchez-Obregón, Rubén, Obregón-Mendoza, Marco A., Enríquez, Raúl G.

“…The crystal structure determination of metal complexes of curcuminoids is a relevant topic to assess their unequivocal molecular structure. We report herein…”
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1,2,3-Triazole nilotinib analogues: Synthesis and Cytotoxic activity by Almazán-Sánchez, Leticia, Ramírez-Apan, María Teresa, Morales-Morales, David, García-Eleno, Marco A., Cuevas-Yañez, Erick

“…Using the CuAAC reaction as a key step, a novel series of Nilotinib analogues was prepared by replacing the imidazole ring in the Nilotinib molecule with…”
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The Antitumoral Effect In Ovo of a New Inclusion Complex from Dimethoxycurcumin with Magnesium and Beta-Cyclodextrin by Obregón-Mendoza, Marco A, Meza-Morales, William, Rodríguez-Hernández, Karla Daniela, Estévez-Carmona, M Mirian, Pérez-González, Leidys L, Tavera-Hernández, Rosario, Ramírez-Apan, María Teresa, Barrera-Hernández, David, García-Olivares, Mitzi, Monroy-Torres, Brian, Nieto-Camacho, Antonio, Chávez, María Isabel, Sánchez-Obregón, Rubén, Enríquez, Raúl G

“…Breast cancer is one of the leading causes of death in the female population because of the resistance of cancer cells to many anticancer drugs used. Curcumin…”
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Anti-inflammatory and anti-bacterial activity, and CYTOTOXICITY of halloysite surfaces by Cervini-Silva, Javiera, Nieto-Camacho, Antonio, Palacios, Eduardo, Montoya, José Ascención, Gómez-Vidales, Virginia, Ramírez-Apán, María Teresa

“…The surface properties of halloysite control its anti-inflammatory and anti-oxidant activity, and cytoxicity properties. •Surface properties determine the…”
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Synthesis, Characterization, and Preliminary In Vitro Cytotoxic Evaluation of a Series of 2-Substituted Benzo [d] [1,3] Azoles by Linares-Anaya, Ozvaldo, Avila-Sorrosa, Alcives, Díaz-Cedillo, Francisco, Gil-Ruiz, Luis Ángel, Correa-Basurto, José, Salazar-Mendoza, Domingo, Orjuela, Adrian L., Alí-Torres, Jorge, Ramírez-Apan, María Teresa, Morales-Morales, David

“…A series of benzo [d] [1,3] azoles 2-substituted with benzyl- and allyl-sulfanyl groups were synthesized, and their cytotoxic activities were in vitro…”
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