Search Results - "Ram, Renee R."
-
1
Lack of impact of pre-existing T97A HIV-1 integrase mutation on integrase strand transfer inhibitor resistance and treatment outcome
Published in PloS one (17-02-2017)“…T97A is an HIV-1 integrase polymorphism associated with integrase strand transfer inhibitor (INSTI) resistance. Using pooled data from 16 clinical studies, we…”
Get full text
Journal Article -
2
A highly potent long-acting small-molecule HIV-1 capsid inhibitor with efficacy in a humanized mouse model
Published in Nature medicine (01-09-2019)“…People living with HIV (PLWH) have expressed concern about the life-long burden and stigma associated with taking pills daily and can experience medication…”
Get full text
Journal Article -
3
Antiviral activity of HIV‐1 integrase strand‐transfer inhibitors against mutants with integrase resistance‐associated mutations and their frequency in treatment‐naïve individuals
Published in Journal of medical virology (01-12-2019)“…The development of resistance to human immunodeficiency virus 1 (HIV‐1) integrase strand‐transfer inhibitors (INSTI) has been documented; however, knowledge of…”
Get full text
Journal Article -
4
Clinical targeting of HIV capsid protein with a long-acting small molecule
Published in Nature (London) (27-08-2020)“…Oral antiretroviral agents provide life-saving treatments for millions of people living with HIV, and can prevent new infections via pre-exposure prophylaxis 1…”
Get full text
Journal Article